Cytomegalovirus transcript analysis

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Analysis of cytomegalovirus

Cytomegalovirus transcript analysis

Cytomegalovirus CMV - this is the fifth type of herpes DNA virus belonging to the TORCH-infections. In blood CMV develop antibodies, or immunoglobulins: IgG and IgM.

IgM appear after one to two weeks after infection and after each multiplication CMV remaining in the body. After a while they disappear forever.

IgM high - the result is positive, denoted POZ.
It means that:
* Infection occurred in the last year;
* Long-standing infection, the virus was suppressed, but again, reproduces.
  • 2. IgM low - negative - NEG.
    It means that:
    * In the last year of infection was not;
    * Available on the virus generated antibodies to cytomegalovirus, and no reproduction.
  • If the patient has other TORCH-infection, the IgM assay may be positive.
    IgG appear a month after infection and remain for life.

    IgG level indicates the time after CMV infection and whether it continues in the organism reproduction.

    1. If IgG raised - has been exposed to the virus before, it has immunity and carriage of CMV.
    2. If IgG low - exposure to CMV was not.

    Possible re-analysis, and if antibodies increased more than fourfold, cytomegalovirus actively propagated.

    Laboratories use different techniquesdetection of antibodies. The analysis of these indicators form the norm, which is required when interpreting the result. cytomegalovirus analysis indicators may be indicated:

    • USD (IU),
    • optical units. - Pu
    • absorbance - OP,
    • u in ml
    • titer.

    Assays for cytomegalovirus appointed therapistpediatrician, gynecologist: planning pregnancy, pregnant women, newborns, children suspected of being infected, HIV-infected, preparing for transplantation and so on.

    Ways of infection:

    • prenatal,
    • airborne,
    • sexual,
    • through the blood.

    Sample - serum. Blood is taken from a vein in the morning on an empty stomach, eliminating fat intake per day.

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