What is psoriasis?
to the human eye skin is constantly changing, living and updated.
Functions of the skin are numerous and worthy of wonder. Without the participation of consciousness
skin protects us from harmful external influences, prevents loss
vital internal components, strengthens the body, prevents
potentially harmful, both internal and external changes
Temperature plays a major role in the immune system and executes
many other functions.
It brings pleasant and if about it
care, adorns the exterior, being necessary as a protective barrier,
allowing to live in this world.
The skin is constantly renewed, and it
it is important to understand what constitutes psoriasis. Normally, it is
completely renewed once a month, or more precisely, every 28 days.
In psoriasis, this process is speeded up, because the skin is trying to renew itself
every 3-4 days. No need to be a genius to understand that in this
deviation from the norm is something wrong.
Flaking scales at
Psoriasis can occur so hard that leads to bleeding
(Sign Auspittsa). Outgoing to the cell surface is not completely
functional, because they do not have enough time to form.
Not only is the exterior view of the patient deteriorates, violated function
skin that is at risk of internal or external
Psoriasis - a chronic skin disease Noninfective.
Its appearance may range from a few small spots on
the body to large areas. It is not contagious and does not spread from
one person to another or from one part of the body other disease.
As psoriasis begin?
You psoriasis begins when you pay attention to the appearance of the rash
covered with silvery scales. Then, deterioration occurs
Spread. And the patient goes to the doctor. Sometimes the first signs
appear on the site of the wound or scratches on the skin. Damage not
It passes, and psoriasis begins to spread around. From attempts
scrape or cut the skin at this place only gets worse. low
humidity, systemic administration of drugs and stress are also
factors that precede the first manifestation of the disease.
There is a theory,
Psoriasis appears most often in areas that are more prone to
stresses and external influences, such as elbows and knees. but
Many patients have a rash where there are no specific
loads, for example on the abdomen or back. Common places of rashes - is
head, elbows, knees, lower back and calf. They may, however, appear
anywhere, including the nails on the hands and feet, as well as sensitive
mucosal surface. Why psoriasis appears somewhere often
and in some cases at least - it is already unimportant, if recovery begins.
There are several types of psoriasis. But, regardless of the severity or manifestations, is one and the same disease.
Feature of this disease that the patient does not feel pain, and it is not even operable immobilized.
Can I cope with the disease itself, or do I need to see a doctor?
If you suddenly find in the knee and elbow joints inconspicuous rash, be sure to go to a dermatologist. Psoriasis
- A serious disease and can be self-harm to the patient. And if
the doctor confirms a diagnosis of psoriasis, do not despair. With modern
therapy methods in most cases possible to achieve proof
remission or clinical recovery.
Why does psoriasis occur?
Psoriasis - polietiologic disease. The causes of psoriasis are also endocrine disorders, changes in the patient's immune system, metabolic disorders, various neuroses and stresses.
Do you suffer from psoriasis, your children are at increased risk of disease
psoriasis. The risk increases nearly doubled if both parents suffer from
The exact cause of psoriasis is still
yet known. There it is the result of two processes - too
rapid skin cell division and inflammation, however, that it is
the impetus for their development remains unclear. Now this issue is being actively
Under the microscope, it can be seen,
that psoriatic skin is inflamed and thicker than usual - at the expense of
sharp thickening of the epidermis (hyperkeratosis). Inflammation causes
T-lymphocytes (a type of white blood cells), accumulating in the centers
disease and attacking the skin itself.
Chronic inflammation causes
skin cells, called keratinocytes, share and pass
cell cycle 4-5 times faster than normal. Rapid accumulation
keratinocytes, in turn, leads to the formation of thick scales.
Over time in the deep layers of the skin there are new blood vessels
that feed actively developing psoriatic plaques. because of
the newly formed vessels of the skin may remain red even after
It is not clear why in psoriasis (as with other
autoimmune diseases) in skin-activated T lymphocytes, but
This process, once started, continues throughout life. how
inactivate or "disable" these T cells without damaging
the immune system in general, and without causing serious side effects -
One of the major problems in the treatment of psoriasis, and to solve it now!
conducted active immunological studies.
psoriasis patients and their family members shows that a disease
there is a genetic or hereditary predisposition, but
it does not mean that all people who have inherited certain genes or
psoriasis patients with brothers and sisters, will certainly get sick (see.
question 25). As far as today, the majority of
genes associated with the development of psoriasis, is responsible for the production of proteins
immune system. Individual genes and groups of genes found in patients
psoriasis are more likely than the general population.
However, most people,
having these genes does not suffer from psoriasis, and in many patients,
In contrast, no such genes. Therefore now genetic analysis
It performed only for research purposes. He does not give any
useful information for the diagnosis and treatment of psoriasis as well as
to make predictions about the course of the disease.
research into the causes of psoriasis have shown that it may arise
specific genes involved. It is necessary to take the next step -
use this information to develop new therapies and
such work is now underway.
Psoriasis is contagious?
Currently completely rejected the infectious theory of psoriasis. It is proved that> psoriasis is not contagious.
There is misconception that psoriasis is contagious.
Uncertainty and fear experienced by people when they first see
It looks like psoriasis, for the most part generated by the fear of becoming infected.
However, psoriasis is not contagious. No contact with the affected skin or
patient care or the use of common items (cups, towels
et al.) can not lead to contamination of psoriasis. Psoriasis - not an infection.
Its cause is not pathogens and white blood cells of
sick, so others this disease is not transmitted.
people do not see the difference between non-communicable and infectious skin diseases.
They can take psoriasis for a fungal infection (tinea, or
athlete's foot), impetigo (staphylococcal or streptococcal skin infection),
a viral infection, occurs with rash or itching. Therefore nekototle
psoriasis patients consider it necessary to briefly explain the new
friends, what psoriasis is and why it is not contagious.
one person in the family sick with psoriasis, and then the same disease
diagnosed in the other, the reason lies in the common hereditary
predisposition, not in physical contact with the patient. For
Most people with psoriasis, physical contact with family
and friends are very important, and others should not be afraid of them.
infectiousness of psoriasis is very common and can be a lot
trouble as the sick and those around them. reliable and
correct information submitted able to dispel at least some of the false
fears that in the minds of the people associated with the disease.
modern knowledge (for example, reading the recommendations of the National
Psoriasis Foundation or other organizations), people suffering from psoriasis,
can lucidly explain that the disease is not contagious. This is the first, with
which is to start a conversation about it.
Although psoriasis is not
contagious, it can spread through the body and to capture different parts of the
skin. The first outbreak could occur anywhere, but most often
it happens to well-defined areas. Although each case
individual, in most patients with psoriasis occurs more or less
looks like. The most common form of the disease - the usual psoriasis -
It affects the elbows, knees, scalp and trunk (Figure 2;. col.
Fig. B and E).
If the patient has an outbreak is detected
psoriasis, a doctor usually examines the typical places, checking for
other foci. Plaques may appear anywhere on the site where the skin was
once damaged, for example in place of an old scar or fresh
scratches (see. question 30). In most cases, the plaques are located at
the body is symmetrical, although some patients are amazed at all
one or two sites.
There are also other forms of
psoriasis, but much less frequently. For example, the disease can strike
armpits (col. Fig. 3) and the groin. This form of the disease called
psoriasis, skin folds, or psoriasis with localization perverted
rashes. Furthermore, there may be hand-podosh-venous psoriasis,
guttate psoriasis, pustular psoriasis and psoriatic erythroderma.
As a rule, each patient there is only one variety psoriasis, although it is possible, and the imposition of several species.
severe cases, the rash can cover the entire body. Redness over 90
% Of the body surface is called psoriatic erythroderma. This is very
serious condition, sometimes even life-threatening. defeat all
skin violates the body's ability to fight infections
and retain moisture, increases the risk of infections. Depending upon the severity
psoriasis and general condition of the patient may require
hospitalization for more careful monitoring and treatment.
At what age is most often manifested the first signs of the disease?
usually begins at a relatively young age, but can occur
any, of the first year of life until old age, when its symptoms often
are uncharacteristic. In some patients, psoriasis occurs after
flu or sore throat. This is not surprising - any infection weakens
Psoriasis most often fall ill in
ages of twenty to thirty years. In children, it is not as
often in elderly and - even less so a correct diagnosis in these
cases, it is sometimes possible to put at once.
Who suffers from psoriasis?
Psoriasis can be anyone, regardless of gender, nationality or presence
other skin ailments. Most commonly occurs from age
teen to thirty years. Sometimes psoriasis diagnosed even
children, but they do it can vyglyadet differently than adults.
some people, the risk of developing psoriasis increased. In particular, this
As for those who have them you are sick or hurt someone of the closest
relatives (parents, grandparents, brothers and sisters).
Other risk factors include psoriasis in more distant relatives
(Uncles and aunts, cousins and second cousins and sisters), psoriatic
artirit someone or seven, the presence of a family history of autoimmune
diseases. Polls psoriasis patients show that 40-65% of these
someone in the family suffers or has suffered from this disease.
many studies of hereditary predisposition to
psoriasis. It turned out that among the genes responsible for the production of proteins
the immune system, there are those that are frequently found in patients
psoriasis and at least - in healthy people.
In the future, this information may
It is useful for therapeutic purposes, but to date
the day of the test system to determine the genotype of people with psoriasis,
industrially available and not practical role in the evaluation
prognosis and treatment decisions do not play.
Risk was assessed in several studies with the participation of the next of kin
(Siblings, twins, children and parents). If one of
twins suffering from psoriasis, the probability of a second sick - 58%
(Output is made on the results of a survey 141 sets of twins).
psoriasis suffers a brother or sister, the lower the risk of developing
- About 6%. If the psoriasis sick one parent, the child
The incidence of less than 20%, however, if both parents are sick, she
increases to 65%. Disease severity and localization of lesions in different
family members may vary.
Psoriasis - is a rare disease?
Psoriasis is considered a rare, almost exotic disease. AT
Indeed, according to conservative estimates, even in the most
prosperous countries and regions suffering from psoriasis of at least 4%
population. And in Scandinavia - up to 8% of the citizens. Statistics provided
different, but it is estimated that psoriasis suffers from 2% to 3% of the US population,
that is, about 4.5 million people. Each year are diagnosed around
200,000 new cases.
The prevalence of psoriasis is different in different
ethnic groups. Among whites it is higher than among blacks, la
tinoamerikantsev, Asians, Indians and Eskimos. The reasons for such
unevenness is unknown, but it is believed that it is related to
family history (see. question 25).
common ordinary, or plaque psoriasis - this form is found
85% of patients (col. Fig. F). Other forms of psoriasis, taken together,
constitute about 15% of cases, although the same person
at the same time can be observed several varieties of the disease.
Guttate psoriasis often occurs in children who have recently had
infection such as a sore throat. Sometimes he quickly passes. All
rare form of psoriasis looks so do not look like normal psoriasis,
that sometimes for a long time can not diagnose or put
The incidence of psoriasis
It varies from country to country, reflecting differences in the ethnic composition
population and the amount of sunlight. Above all (4-5%) it is
Northern Europe, and following all - in some countries of South America and
Samoa, where no cases of psoriasis was found. In
He found the same men and women often.
10-30% of patients with psoriasis may develop psoriatic arthritis. In
it appears most 5-10 years after onset of the disease, but
rarely happens and its the first symptom.
Does psoriasis Dangerous?
Psoriasis does not affect overall health.
If it is widely spread, it can certainly cause
discomfort, unpleasant sensations in the skin and emotional difficulties
the plan may affect work and leisure. Fortunately, the majority of people,
psoriasis patients has small skin lesions that although
it is unpleasant, it does not alter their way of life.
cases in people with psoriasis may develop a form of arthritis,
called psoriatic arthritis. the need for appropriate
medical examination to confirm the diagnosis. Although not
always, psoriatic arthritis most often seen in people with vastly
common psoriasis, rather than local distribution.
Psoriatic arthritis can affect people of all ages.
Is it possible to cure psoriasis?
there is a means for the full treatment of psoriasis, but there are many
medicines and medical treatment, which can reduce and control
psoriaz, often for quite long periods of time. Psoriasis
itself may come and go, often with long periods
In most cases, however, psoriasis constant. He can
come and go without any apparent reason. Psoriasis is not necessarily
deteriorates with age. Psoriasis may occur at any age from
infancy to old age. Psoriasis often remains small
restricted areas and never distributed.
Today, you can not completely recover from psoriasis. As
Many autoimmune diseases, the methods of treating it that suppress the immune
system. Unfortunately, none of the current treatments can not
reduce the activity of immune cells forever. current funds
removed the symptoms of psoriasis, but are not able to influence its deep
reason: the attack of the immune system in the skin.
Most patients with psoriasis is acute, then it subsides. many
there are times when it disappears completely. But usually, the disease
still it returns. Because the immune system is aimed at
attack the skin, it occasionally happens.
media and then advertised next
"Miracle" remedies for psoriasis. However, since psoriasis
It has a complex and ambiguous nature, and the immune system is difficult
"Retrain", the majority of patients are in need of constant care.
Therefore, although many techniques are cleaned for some time symptoms
psoriasis, any reports of complete healing should be carefully
The most realistic goal for the majority of
patients - is to find an acceptable balance between the control of the condition
and the amount of time, effort and money that they are willing to spend on
treatment. Since all medication is unsafe, you should always evaluate
the ratio between their therapeutic effects and side effects.
I hope that in the future healing tool yet appear. Immunologists
and dermatologists continue to study diligently, formatsevticheskie
companies and large health centers are also involved in this issue.
Psoriasis is on the crest of scientific interest; consistently reported
new developments and discoveries in this area.
What worsens the psoriasis?
Some factors that may worsen the course of psoriasis. Their
good to know. But remember, psoriasis can flare up without any
apparent reason. Below - some of the factors that worsen
psoriasis (at least pimenitelno to most people)
Damage to the skin and scratching
scratches and tan - all of which can activate psoriasis. You must
try to stop the mechanical irritation of your psoriasis if
possible. Psoriasis can develop for the first time on areas of the skin,
damaged by scratches, burns or contagious diseases.
Most people with psoriasis, moderate sunbathing is very
useful, but sunburn can cause psoriasis flare up again. small
number of people (about 10%) believe that their psoriasis worsens by
Sun in all its numbers. If you have white skin, perhaps you
You will need sunscreen to protect against sunburn.
relationship between diet and psoriasis has not been found; but there
some important guidelines to follow.
A healthy balanced diet is important for good health. Some
people find that their psoriasis worsens with excess weight - so that
weight loss is useful for controlling psoriasis. Some people pay
note that alcohol activates any type of psoriasis
Patients notice that stress aggravates the course of their psoriasis. If this
occurs, it is worth trying to find ways to avoid stressful situations.
taken for other reasons, worsen psoriasis, but of course,
not in every case. These drugs include in its membership: Gold,
lithium, beta blockers such Inderal, used for hypertension. You
You should tell your dermatologist what drugs you are taking. If
you have questions about this, be sure to ask them.
diseases of the throat and upper respiratory tract - especially streptococcal
Infection can worsen your psoriasis. More often it is seen in children and