What is ichthyosis, symptoms and course
Ichthyosis - a hereditary disease characterized by generalized violation of skin keratinization.
The etiology is unknown. There are several clinical forms,
due to the different groups of mutant genes, the biochemical
defect which is not completely deciphered. Attaches great importance to
vitamin A deficiency, endocrinopathies (hypothyroidism
Average (vulgar) ichthyosis
- The most common form. Inherited in an autosomal dominant manner (inheritance is passed on to children
parents with congenital form
It manifests itself in early childhood and is characterized by dryness of the skin,
formation of scales on its surface whitish or grayish color
in severe cases, take the form of brown plates and rough boards,
dense to the touch. Leather large skin folds and folds remains
unaffected. On the face peeling is usually negligible, on the palms and
soles underlined drawing
skin lines. Sweating is reduced, it is possible nail dystrophy
plates and hair. Ordinary ichthyosis often combined with atopic
dermatitis, seborrheic dermatitis, bronchial asthma.
What is congenital ichthyosis
Congenital ichthyosis is expressed at birth of the child,
divided into fetal ichthyosis and ichthyosiform erythroderma. ichthyosis
the fetus is rare, inherited in an autosomal recessive manner (possibly birth
a sick child from healthy
develops on the III-V month of pregnancy. At birth, the baby's skin
covered with thick layers of horn, reminiscent of tortoise shell
or crocodile skin. Mouth stretched, sedentary, or
on the contrary, sharply narrowed. Children often preterm and unviable.
ichthyosiform erythroderma (a group of human diseases manifested mainly inflammatory reaction in all of the skin) the skin at birth
thin dry film of yellowish, resembling collodion, after
which revealed persistent rejection of all diffuse hyperemia
skin (including skin folds) and lamellar desquamation,
the severity of which is enhanced with age, and erythroderma
weakens. There are also a variety of congenital bullous
ichthyosiform erythroderma - epidermolitichesky ichthyosis, characterized
more severe with the formation of bubbles. In congenital
ichthyosiform erythroderma possible eye damage (ectropion,
blepharitis), nail dystrophy, hair and keratosis of palms and soles, lesions
nervous and endocrine systems. The disease lasts a lifetime.
The treatment of ichthyosis
Vitamin A inside drops of 2 to 30 times
day for repeated long courses Aevitum / m or
capsules tigazon, B6 and B12 vitamins / m, iron preparations, arsenic,
tireoidin (under control of the thyroid gland). In severe cases,
ichthyosiform erythroderma - corticosteroids inside.
Showing as ultraviolet radiation, sea bathing, bath
adding borax, soda, starch, sea salt. Outer: fat creams
addition of vitamin A, 10% cream
sodium chloride, urea, lard.