What is ichthyosis vulgaris

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  • vulgar ichthyosis
  • Diagnosis vulgarngo ichthyosis


  • vulgar ichthyosis

    Vulgar ichthyosis (ichthyosis vulgaris) - the disease is inherited
    autosomal dominant with high penetrance (the frequency with which this feature is controlled by one or another gene) gene. Initial signs
    disease detected in the first months of life. maximum
    the development reaches to 10 years of age and continues throughout
    life with improvements in the summer and during puberty.
    The disease can occur with varying intensity. Disease
    common, is characterized by dryness, thickening of the skin, but without the inflammatory changes, without
    erythema (redness of the skin strong). Especially pronounced dryness and flaking on the extensor
    surfaces of the extremities, in the elbow and knee joints. Leather
    axillary, elbow, popliteal pits, perineum, palms and soles
    It is not changed. In children up to 4-5 years involved in the process and the skin of the face. AT
    forehead and cheek areas can be seen lamellar or scaly
    scales grayish muddy color.

    Depending on the color of the flakes, their appearance, the expression
    dry skin, there are several types of clinical vulgar
    ichthyosis.

    What is ichthyosis vulgarisXeroderma (xerodermia) - Initial, the easiest
    kind of ichthyosis, in which there are skin dryness, peeling
    pityriasis nature, mainly on the front surfaces
    upper and lower extremities, and partly on the skin of the trunk.

    Simple ichthyosis (ichthyosis simplex) - A second
    intense expression variety. Dry skin is expressed
    more significant, there are copious amounts of lamellar scales, tightly
    adjacent to the thickened, dry, hard and rough skin.

    Brilliant ichthyosis (ichthyosis nitida) manifest (manifest)
    significant accumulation of horny scales, different pearlescent
    shine or have a slightly shiny, as if varnished surface.
    In the presence of whitish pearly scales use the term "white
    ichthyosis. " Sometimes the scales become thicker, denser, acquiring
    dark gray in color and are arranged ribbon-like, tightly adhering to the skin
    and distinguishing between deep grooves. This option clinical form
    ichthyosis called serpentine (ichthyosis serpentina). The most severe
    is a kind of styloid ichthyosis (ichthyosis hystrix), while
    wherein the front surfaces of the limbs are arranged clusters
    thick horny masses in the form of pins protruding by 1 - 10 mm above the
    skin surface resembling porcupine quills.

    Hair and nails with milder forms of ichthyosis are not changed and the total
    the condition of patients is satisfactory. However, in infants with
    severe forms of ichthyosis, dry hair, thinning, sparse.
    Observe various onychodystrophy. Patients ichthyosis due
    low flow and sebaceous excretions and breach of thermoregulation
    astenizirovany lag behind in the physical and intellectual development. they
    marked immunodeficiency, predisposition to the development of
    piodermitov, pneumonia, otitis media, the emergence of eczema, neurodermatitis,
    psoriasis. Imbetsillopatiya and disadvantages of forming phenotype characterized
    children with severe forms of ichthyosis.



    Diagnosis vulgarngo ichthyosis

    Clinical and morphological manifestations of all varieties
    ichthyosis vulgaris differ constancy. All forms of the disease
    occur in childhood. Therefore, the process of diagnosis is not
    presents difficulties. The differential diagnosis with acquired
    ichthyosis based on the presence in acquired ichthyosis
    avitaminoznogo state, especially vitamin A deficiency, blood diseases
    such as leukemia or Hodgkin's disease.

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