What is herpes?
Herpes - an infectious disease caused by a herpes simplex virus (HSV).
The most common virus infects:
- eyes - conjunctivitis, keratitis
- mucosal face
- mucous membrane of the genitals
- central nervous system - encephalitis, meningitis
The disease is transmitted through sexual contact
(Genito-genital, genital-anal, oral-genital) at
contact with the patient or carrier of herpes simplex virus.
Infection is likely to happen when
contact with patients during relapse (recurrence) of the disease, as well as when there is a
isolation of the virus without showing clinical symptoms. maybe
infection during oral-genital contact, if herpes partner
In pregnant women, the virus can cause
violation of pregnancy, spontaneous abortion, premature birth.
During childbirth possible HSV infection of the fetus.
The probability of transmission, as well as the development of neonatal herpes in the child depends on several conditions:
- the level of neutralizing antibodies in the mother, who went to the fetus transplacental (in utero)
- Local levels of antibodies that bind to the virus in the genital tract
- duration of anhydrous period
- having a baby skin damage during delivery
Infection may occur baby and after the birth, it depends on the
how many active herpes symptoms in the mother.
There are three stages of lesions of genital herpes:
- I - the defeat of the external genitalia
- II - herpetic urethritis, kolpity, cervicitis
- III - herpetic endometritis, cystitis, salpingitis
In women, herpes blisters usually form on
small and large labia, clitoris, cervix. However, infection
may penetrate into the lining of the uterus, tubes, epididymis ascending
means. In place of the bubbles formed ulcers that do not bleed, and
After healing does not leave scars. Herpes Appearances can be
triggered by other infections, sexually transmitted diseases.
Recurrences usually occur after menstruation or sexual
Men are affected more often extreme
flesh, the head of the penis, balanopreputsialnaya groove. For men
characterized by recurrent nature of the disease, in which form
herpes blisters and erosions. The infection can cause
herpetic urethritis and balanoposthitis (inflammation of the glans penis).
Given that the herpes symptoms may be
similar to the symptoms of other infections, sexually transmitted infections,
One of the main tasks is to identify the disease.
For the diagnosis of HSV used the following methods:
- virological methods for the detection and identification of herpes simplex virus
- polymerase chain reaction (PCR)
- detection of HSV antigens
- Check immune response to HSV
- cytomorphological methods
- evaluation of the immune status
The presence of HSV antigen in biological material is determined by serological methods:
- neutralization (RN)
- immunosorbent assay (ELISA)
- radioimmunoassay (RIA)
- complement fixation (RSK)
- gemmagglyutsinatsii passive reaction (PHA)
Herpes Treatment requires an integrated approach and shall be appointed only after the diagnostic studies.
For the treatment of herpes is used:
- antiviral drugs
- estrogen interferon
- interferon inducers
- local media
The main antiviral drug is
Zovirax (acyclovir, a synthetic purine nucleoside), which through
inhibition of viral DNA synthesis is able to successfully deal with HSV. AT
During treatment of herpes, until the complete disappearance of clinical manifestations,
the patient is recommended to refrain from sexual activity. All sex
infected partners should be tested and, if
and treatment needed.
For prophylaxis of herpes vaccine is used,
it also can be used for immunotherapy of patients with HSV. If the patient does not
suffering immunodeficiency, it would make 5 injections 2-3 days not
at least 2 times a year. If the patient suffers from immune deficiency and relapses
diseases are repeated at least 1 time per month, the vaccination is carried out
1 every 7-14 days in an amount of 5 injections.