Listeriosis, ways of infection
Listeriosis - an infectious disease caused by a bacillus called Listeria. The natural "reservoir" of infection are rodents and some pets.
Basic ways of infection are two:
- nutritional (ie, germs enter the body with food, contaminated by them);
- intrauterine (congenital listeriosis).
The development of infection plays an important role state of the human immune system. Importantly, however, that among the various forms of listeriosis
specially isolated "listeriosis pregnant." Examination of a large number of
Women - mothers of children with congenital listeriosis has shown, first,
that most of them were not typical during pregnancy
listerioznoy manifestations of infection, and secondly that
not every bacteriocarrier leads to intrauterine
infection of the fetus.
Upon infection of the fetus during pregnancy, as the
usually develop acute chorioamnionitis, leading to stillbirth
or premature delivery, infection of many organs and
fetal systems. Upon infection of the newborn during birth signs
congenital listeriosis occur in 1-2 weeks
after childbirth. The disease often occurs quite hard, Listeria can
determine bronchopneumonia, enlargement of the liver, jaundice, and other
serious diseases and symptoms.
Diagnosis and treatment of listeriosis
Therefore, early diagnosis is extremely important that sufficient
insidious disease. In some cases, the expectant mother is
guard? When repetitive tonsillitis, inflammation of the ovaries,
cervical, if in the past several miscarriages or
stillbirths. If a woman is pregnant, the listed indications
You can add and pathological course of pregnancy.
In acute forms of listeriosis prescribe antibiotics
tetracyclines (tetracycline 0,250,4 g of 6 hours) for
all febrile period and another 5-7 days, penicillin (000 IU 400
after 4 hours), erythromycin (0.25 g after 6 hours). More effective
the combination of ampicillin plus gentamicin or tobramycin with penicillin
(Gentamicin and tobramycin almost do not penetrate the blood-brain
barrier, so the neural forms of listeriosis theirnot indicated). In severe forms of listeriosis causal treatment is continued until the 1421 days of normal temperature. When listeriosis pregnant tetracyclines is not indicated (risk of teratogenic effect), it is recommended penicillin.
Prognosis is poor in children under 1 year and adults older than 60
years, as well as in patients with severe concomitant diseases (cancer, AIDS,
et al.). Pregnant listeriosis can lead to serious
Fetus. After listerioznyh meningoencephalitis can be
persistent residual effects from the CNS (central nervous system).