Gout - Chronic disease, manifested by the deposition of uric acid salts in organs and tissues. The disease proceeds in the form of seizures that are replaced by light gaps of various duration. What are the signs of exacerbation of gout and what they are leading?
Content
- Moreover, a gonment occurs?
- Symptoms of exacerbation of gout
- Other manifestations of gout
- What happens next?
«Nothing special. Mrs. Greenhouse left for six weeks in Menton,
but a few days ago returned. Major had an attack of gout».
WITH. MEEM. Pies and beer
This disease inspired to the creativity of the Writers XIX — The beginning of the 20th century: its descriptions are often found in the literature of that period. Apparently, the disease was so commonly phenomenon, which was perceived as an integral part of the well.
From a scientific point of view, gout — This is a chronic disease, the occurrence of which is associated with a violation of metabolic processes, in particular with a violation of the exchange of purine bases, leading to accumulation in the body of uric acid. The disease is manifested by attacks of acute synovitis and arthritis, deposition of uric acid salts in various organs and tissues.
Moreover, a gonment occurs?
The etiology of this disease is colorfully described in the titles and novels of the XIX century. Magnificent feast, abundance of birds, meat, oily, fried dishes, rustling river wine and beer. Today it has been proven that it is the constant consumption of oily meat, chicken and dry wines leading to a sharp accumulation in the body of urates and the exacerbation of gout.
If you dig deeper, the immediate cause of gout is a shortage or insufficient activity of enzymes involved in purines metabolism. Along with this, the development of the gout can cause kidney disease, accompanied by a violation of their function, the delay in the uric acid salts in the body, the deposition of urates in the tissues and the development of gouty inflammation.
Symptoms of exacerbation of gout
In eight cases out of ten gap flows in the form of sharp attacks of arthritis arising after abuse of fatty food and alcohol, after supercooling or injury to the joint.
Sometimes the exacerbation of the gout is preceded by a short period of production, weakness, increased fatigue, mood change, nervousness, headaches, increase body temperature up to 37.2–37.4 degrees Celsius. Already at this stage there may be indefinite sensations in the joints in the form of fragments, gravity and stupid pain.
The bout itself is usually beginning at night, against the background of full health. In the area of the Bone of the Big Foot, there is a sharp pain, the joint quickly swells, the skin is stretched over it, it becomes smooth, shiny, hot, red, and then the crimson-blue. Temperature of the body rises to 38–39 degrees, patient turns out to be literally paralyzed pain, but can not stand up — The joint is completely immobilized.
When subacute, the gout shape is affected mainly the joint of the thumb, the pain is not strong and changes in the tissues of the joint are not too pronounced.
The rheumatoid form of the gout resembles rheumatoid arthritis, proceeding with the damage to the small joints of the brush or wrist, but does not capture more than one bone joint.
The phlegmonous form of the disease occurs. The aggravation of the gout in this case is accompanied by fever, chills, sharply pronounced inflammation of the joint, externally resembling purulent melting of tissues in infectious arthritis.
The periatric form of the gout is found, in which the tendons of the muscles adjacent to the joint are affected, for example, the heel tendon in the place of attachment to the ankle joint.
Other manifestations of gout
In addition to arthritis, the aggravation of the gout can have other symptoms. Accumulation of uric acid salts in the skin after 5–6 years after the start of the disease leads to the formation of tofuses — Surrounded by a connective tissue of gouty subcutaneous nodules having a yellowish color and containing urates crystals. Tofes most often located on the back surface of the forearm, elbow joints, the joints of the fingers and legs, on the hips and the legs. They can be found on ear sinks, on the forehead, in the area of the nose cartilaginous partition.
The aggravation of the gout can lead to the dilution of contents of tofuses and the allocation of its outwards through the fistula formed on the skin. In contrast to conventional uluses, the contents of the gogress nodules is not pus, does not contain any microorganisms, since urates have bactericidal properties.
In almost half of the patients, the bouts of the disease are accompanied by renal columes, manifested by sharp pains in the lumbar region and along the ureterals, impaired urine release and often complicating pyelonephritis.
What happens next?
The aggravation of the gout, that is, its attack, usually lasts long, sometimes passes throughout the day, sometimes stretched on 5–10 days. Pains gradually disappear, the swelling of the joint will fall, the skin over it acquires the usual color, the functions of the joint are restored. Over the years, the gap is aggravated more often, the bright gaps become shorter. In severe cases, gouty status develops — the state when the exacerbations of the gout continuously replace each other and turn the patient into a disabled person.
Repeating inflammation lead to the deformation of the joint, restricting its mobility. The disease extends to other articulated joints, the gouty polyarthritis arises, leading to restriction of the patient's working capacity.
Gout — severe illness, and despite the fact that the heroes of the novels of the XIX century were frivolously relate to short attacks of the ailment, reality turned out to be much more gloomy. In a third of patients, gougher nephropathy develops, leading to a resistant impairment of kidney function and renal failure and in 40% of cases ending in death.
Somerset Moem B «The edge of the razor» Colorfully described the case of nephropathy for gout: «Elliot is an attack of urrisingia, and the doctor considers his condition a heavy. This time the attack passed, and he is better, but the kidneys are seriously amazed and the complete recovery is impossible <...> His face pours a terrible blue pallor, the sickening smell is coming from him characteristic of his illness... He falls into whom».
