Systemic lupus erythematosus: you need to know about it?


  • Immune "scrapping"
  • What are the symptoms of lupus?
  • How to diagnose SLE?
  • How to treat SLE?

    Immune "scrapping"

    Systemic lupus erythematosus: you need to know about it?The reasons for this serious illness has not yet been clarified. It is possible that for the debut of the disease, a combination of circumstances:

    • genetic background (genetically determined characteristics of the immune system)
    • unfavorable to this particular organism environmental factors (environmentally caused damage to the immune system)
    • frequent inflammatory diseases (tonsillitis, sinusitis, pharyngitis)
    • chronic diseases that can lead to a "scrapping" of the immune system - chronic tonsillitis, chronic inflammatory gynecological and urological diseases.
    • As soon as it is known that systemic lupus erythematosus - a chronic immune disease, means all the manifestations of the disease - a consequence of immune defect, with both cellular and humoral.

      What are the symptoms of lupus?

      People with SLE are observed starting fever, fatigue, weakness, weight loss is very fast ...

      In the third case on the wings of the nose and / or on the cheeks of the patient appear reddish or reddish-purplish plaques - the so-called "butterfly". By the way - it is not alwaysfound in the classic version; redness can take very different forms and localized in different places. For example, blyashkovidnye erythema as the equivalent of "butterfly" can be found on the scalp. Or on the palms.

      Pain in the joints - Is one of the most constant and almost a classic sign of lupus process (almost always occur).

      In a third of all cases of disease detected pleurisy (Inflammation of the membranes of the lungs); a little less - pericarditis and myocarditis (Inflammation of the pericardium, heart or bags, and cardiac muscle, respectively) with arrhythmias, heart failure, etc.

      The vast majority of patients with systemic lupus erythematosus suffer renal disease. Often in the form of glomerulonephritis.

      Suffering and the central nervous system - Headaches (sometimes very strong)depression, seizures, psychosis. On the part of the peripheral nervous system are frequent senestopatii (feeling of "pins and needles", transient itching, unpleasant sensation of the touch of clothing, etc.).

      Do not remain aloof and digestive tract - Frequent complaints of pain in the abdomen (affectedvessels supplying the digestive tract organs, peripheral nerves innervating these bodies). It affects the stomach, liver, pancreas. There is even such a definition - lupus pancreatitis.

      Slowly evolving anemia (We all know the term), thrombocytopenia (reduced platelet count), leukopenia (reduction in the number of white blood cells).

      Sometimes the onset of the disease may become spontaneous abortion (Miscarriage) in a pregnant woman, or the identification of fetal death (usually after the first trimester).

      About a quarter of cases develop Raynaud's Syndrome and even a quarter - Sjogren's syndrome **.

      How to diagnose SLE?

      What is required in terms of laboratory diagnosis if you suspect at this disease - systemic lupus erythematosus?

      And that's what we must do - go to the local general practitioner and ask him to give you directions to the lab to perform:

      • complete blood count (whether increased ESR - erythrocyte sedimentation rate);
      • blood tests for rheumatoid factor;
      • determination of antinuclear antibodies (they are almost always found in the case of illness).

      How to treat SLE?

      Treatment of systemic lupus erythematosus veryspecifically and strictly individual. I would like to focus on cases that the prognosis for her much more favorable than it is often made of thinking, speaking and writing. And rightly initial treatment, as well as the elimination of triggering factors (psycho-emotional stress, sun exposure, use of sulfa drugs, and oral contraceptives) affect the course of the disease, making it more "soft". It is necessary to know.

      *Raynaud's syndrome - Narrowing of the blood vessels in the fingers and toes, which manifests itself in the fact that your fingers are cold, white or blue with the slightest cooling or agitation.

      **Sjogren's syndrome - Dry mucous membranes (mouth, eyes) due to the fact that disrupted the function of the salivary and lacrimal glands and stops or reduces production of saliva and tears.

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