Gout symptoms occur if the bodytoo much uric acid - purine derivative. Directly provoke symptoms of the disease monosodium urate crystals that form in the joints due to excess uric acid.
Uric Acid By-Producthuman life, the result of the breakdown of purines; normally present in the blood in a certain amount. Purines are vital components of any cell, especially its nucleus. A small part of them is formed in the body, but they are mainly supplied with food. Purines are found in almost all products (in particular, there are a lot of them in meat, fish, black tea, coffee and cocoa). In the body, they break down to uric acid and are excreted in this form. If the normal metabolism is impaired, that is, uric acid is produced more than it is excreted, or it is retained in the body, the level of uric acid in the blood rises, which leads to the formation of crystals and the development of gout.
If the kidneys are not able to excrete urineacid, its level in the blood rises, the so-called hyperuricemia occurs. This metabolic disorder is a genetic disease. If elevated uric acid levels go unnoticed for a long time or if left untreated, it will eventually lead to gout. That is why it is important to recognize the initial symptoms of developing gout in time and immediately begin to treat it. One in one hundred people in the world and seven percent of older men suffer from gout.
How to recognize the symptoms?
Called salts monosodium urate arthropathy(In other words, gouty arthritis) - a term which designates recurrent attacks of painful joint inflammation. There are three stages of gout (some experts distinguish a fourth - intercritical asymptomatic period).
Asymptomatic hyperuricemia - Stage of the disease, in which the serum urate level increased, but the symptoms of arthritis, tophus or uric acid stones are still missing.
Acute gouty arthritis - Extremely painful arthritis usually firstone of the joints, but later in the process involves several joints. At this stage, symptoms appear within two weeks in the absence of treatment and lasts less than two weeks, if the disease started to arrest. Also, disease can occur implicitly, when a period of weeks, months or even years, the patient does not notice any signs of gout.
Chronic tophus - Acute attacks of joint pain(Mostly the legs). The crystals were formed as a result of excessively high concentrations of uric acid can form a so-called tophi -mnozhestvennye gouty nodules under the skin. At this stage it is also possible the formation of kidney stones.
At the stage of acute gouty arthritis more oftenthe big toe suffers, and the classic symptoms of gout are obvious redness, swelling, fever in the area around the affected joint and excruciating pain.
Gout is more common in men.elderly women after menopause and people with kidney disease. The development of gout is primarily due to diseases such as obesity, hypertension, hyperlipidemia and diabetes. Gout is a hereditary disease, so if your older relatives have noticed (or have noticed) gout symptoms, be especially careful about your joints.
Typical gouty attack
- The onset of an attack is usually rapid. Often, gout symptoms (sensation of heat, swelling, redness, and soreness) occur at night.
- Over the next eight - twelve hours of pain increases, varying from mild to very severe.
- Ninety percent of gout affected the big toe. A little less - the joints of the midfoot, ankle, heel and ankle, and even rarer - the joints of the wrist, fingers and elbows.
- When gout is manifested in the lower limbs, the patient is difficult for just walking on foot.
- Associated symptoms of gout attacks may be fever, chills, and malaise.
The main goal of any ailing with gout -prevent or at least minimize future gouty attacks. Begin treatment at the earliest stages of the disease and make lifestyle changes and nutrition - the first thing to do man with a diagnosis of "gout."
Test: "Gout: true or false"
Gout and pseudogout (second name - falsegout) is very similar in its manifestations, but are caused by different reasons, and therefore treatment of these diseases is not the same. What do you know about each of these diseases?
Here you can take this test: “Gout: true or false?”