Nephrite kidney in children — The inflammatory disease is more often a bilateral, characterized by the lesion of the renal tubules and parenchyma. Hereditary jade in children, otherwise — Genetically determined by alport syndrome, begins in another childhood. About the causes and symptoms of the disease in this article.
Content
Hematuria,
Sometimes proteinuria and progressive impairment of renal functions with the formation
chronic renal failure, very often combined with deafness and
vision disorder are signs of hereditary jade in children. Long
observations of several generations of one family starting from 1902 when
Initially, hematuria and Uremia was observed, and he was subsequently revealed
and eye damage, allowed scientists after a few decades to identify
The genetic basis of mutation in the Collagen gene.
W
Most patients with jade in families have relatives with kidney disease,
reduced hearing and weakened vision. Today on the basis of perennial
Research data Clinical manifestations are considered as signs of one
Diseases — jade kidneys in children or syndrome
Alport. To identify carriers of a mutant gene, the genetic
Testing, but in 20% of cases there is no significant relationship between related bonds and
hereditary predisposition, it suggests high frequency
Spontaneous mutations.
Options of hereditary nephritis
Children have more
Total distinguishes 3 types of hereditary jade:
-
syndrome
Alport with hematuria, hearing loss and eye damage; -
hereditary
Nephritis without hematurias with hematuria and the progressive development of chronic
renal failure; -
family
Benign hematuria is characterized by a favorable course of illness without forming
renal failure.
Based on
Alport Syndrome Lies Defect Collagen Structure Basal Membrane Kidney,
ear and eyes, disease is inherited by dominant type and manifests itself certain
shifts in the state of the immune system.
First signs
hereditary jade in kids
Revealed usually under the age of three years. During this period, especially attentive
There should be parents of a child with a virus infection or an angina.
Very often precisely control analyzes after suffering from the disease or
The design of the baby in the kindergarten is the starting point that reveals
Nephritis in children. Well-being in the hereditary form of the disease at the beginning almost no
Hematuria suffers the main sign — blood detection in urine.
An increase in hematuria is observed in infectious diseases
respiratory tract, physical exertion and preventive vaccinations. For
attentive mom it should be a signal to further in-depth
Survey of the child and the strict execution of the instructions of an nephron specialist
or urologist. No further deterioration in the state of the kid is not excluded: inxication appears,
Pallor, headaches, muscle weakness, decrease in blood pressure,
especially in boys, sometimes impairment. Reducing hearing in a child can
happen in any time, but most often noted in 6-10 years, it can be
One of the first symptoms that the parents should alert. In this
The period of 20% of children is observed changes from vision, as well as first
Some, and then a significant lag in physical development. Not
laying out, and without waiting for that everything will pass with age, parents should
Immediately go to the doctor, fearing the development of renal failure.
Timely diagnosis and treatment — recipe for success
Diagnosis of jade
Based on the identification of family history, the presence of relatives or at least one
man in the family of hemuckiness, hematuria or Reduction
vision. Differential diagnosis is carried out with glomerulonephritis and renal
insufficiency.
Disease therapy
carried out in the nephrological department of the hospital in compliance with the full
diet with sufficient amounts of proteins, fats and carbohydrates accompanied by
Medicinal therapy. Specific treatment of hereditary nephritis not
There is all therapeutic and preventive measures, including long-term
Stay in the fresh air, are aimed at preventing renal reduction
Functions. In the presence of hematuria, phytotherapy is recommended, blackfold juice
Ryabins, scales of nettle and yarrow. For children suffering from hereditary jade,
Preventive vaccinations are excluded.
