Nitroglycerin: Application and features of action

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Nitroglycerin: Application and features of actionNitroglycerine — The well-known ambulance drug in cases of acute myocardial infarction and acute left-deceased failure, successfully used to relieve angina attacks. He has long established itself as an effective antiagonal, vasodilator and coronairodilative medication. This tool can remove spasms and relax the smooth muscles of the walls of the vessels, expand the peripheral veins and quickly reduce the preload on the heart, expand large artery and reduce postload. This is important in cases of the need to reduce the needs of myocardium in oxygen. With proper use, nitroglycerin normalizes heartflow. With myocardial infarction, the medicine does not allow to develop acute arrhythmias representing the danger to life of a person.

Features of nitroglycerin

People suffering from coronary heart disease and walls of angina, nitroglycerin helps to work out endurance in terms of physical exertion and reduce the number and degree of exacerbations. In surgical interventions, this drug is used to prevent hypertensive reactions (significant and acute lifting of blood pressure).

The tool may cause tolerance with long or frequent use, so you need to take breaks.

Features of Nitroglycerin
Nitroglycerin is convenient for use due to the diversity of its dosage forms: from dosage subwoiling aerosols before the film for sticking to the gum or ointment. It can be taken orally, sublingual (under the tongue), buccally (for the cheek), intravenously, transdermal (plaster) and dashing (ointment). The rate of its action and the focus on a specific clinical situation depends on the form of the drug. For example, the attack of angina can be removed in just a minute and a half when using sublingual and buccal preparation types.

Such drugs require careful study and compliance with the instructions for use, so be sure to familiarize yourself with both the testimony and contraindications of the drug.

Facts that need to know:

  • With acute myocardial infarction or acute heart failure, nitroglycerin can be used only with careful observation of the patient;
  • In the fight against angina, it is impossible to drastically stop taking the drug, as you can provoke the cancellation syndrome;
  • during pregnancy and during the lactation of the use of this tool it is better to avoid;
  • intravenous administration of nitroglycerin is possible not only in cases of acute myocardial infarction and the complications of left-oscillageless insufficiency, but also in the edema of the lungs;
  • It is impossible to take the drug to people with arterial hypotension (reduced arterial pressure), with a closed-coronal glaucoma with high intraocular pressure and increased sensitivity to nitrates to which this tool refers;
  • Elderly to take medicine with caution, preferably under the control of the doctor;
  • During the period of receiving nitroglycerin, you should not get behind the car's wheel or engage in work requiring the speed of the reaction.
  • It is necessary to exclude alcohol, since blood pressure can «Collapse»;
  • Do not chew capsules or tablets, since the excess amount of the drug can do into the blood and cause an overdose;
  • With urgent states (acute myocardial infarction and acute left-forthcoming failure) To achieve a faster result, it is better to take nitroglycerin sublingual or buccically (under the tongue or for the cheek).

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