Basic symptoms and treatment of thyrotoxic crisis


  • The mechanism of development of thyrotoxic crisis
  • Basic symptoms of the disease
  • Treatment of thyrotoxic crisis

  • The mechanism of development of thyrotoxic crisis

    Tireotoxic crisis - this complication may occur in untreated patients after unreasonable cessation of tireostatic preparations, after receiving a radiative iodine or in the first days after removal of the thyroid area. With an undiagnosed or blighted diffuse toxic zob, thyrotoxic crises can provoke mental injury, sharp surgical or infectious diseases, traumatic or insufficient anesthetics during surgery, as well as physical activity, intoxication, toxicoinfection, childbirth and other factors that violate the normal life activity of the body.

    The starting mechanism of the thyrotoxic crisis is a sharp increase in the blood of thyroid hormones.

    Thyrotoxic crisis is more often developing within a few hours, less often - gradually, within a few days. After surgery about the removal of the thyroid area, it is usually evolving after 6-8 hours, less often - on the second - the third day, the second day, after receiving the radioactive iodine - at the beginning of the second week.

    Basic symptoms of the disease

    In the clinical picture of the disease, you can clearly identify 2 periods:

    • Excitation period
    • Period of gradually increasing cardiovascular failure

    Basic symptoms and treatment of thyrotoxic crisisEarly symptoms of the beginning or threatening thyrotoxic crisis is: increase temperatures up to 38c and more increasing tachycardia, insomnia, stubborn vomiting, headache, sweating, diarrhea, characteristic posture «with scattered hands and legs».

    Thyarecic crisis is accompanied by a sharp increase in the main clinical symptoms of diffuse toxic goiter. Patients complain about the absence of appetite, often observed disorders from the gastrointestinal tract. The patient constantly sweats, it bothers the general weakness, the fear of death. Patient's face hypertized, masca, often with a frozen horror expression. The eyes are widely disclosed, flashing rare, gradually comes tissue oxygen starvation, a suffocation appears. Breathing Frequent, Surface. Temperature can be increased to 40 s. Pulse reaches 200 shots per minute, arrhythmias appear.

    With the further development of the crisis due to increasing oxygen starvation and impairment of thermoregulation, mental motor arousal arises in the flesh to acute psychosis, hallucinations, delirium with temporary permanent of consciousness. Patients take a characteristic posture with scattered hands and legs. There are frequent and random movements of the limbs. After 12-24 hours, sharp muscular weakness are developing to complete adamis and loss of consciousness. The body temperature rises to 42 degrees, the pulse disappears, arterial pressure drops, and the patient dies with the phenomena of cardiovascular failure.

    Treatment of thyrotoxic crisis

    Basic symptoms and treatment of thyrotoxic crisisTreatment of thyrotoxic crisis is aimed at reducing the level of circulating thyroid hormones circulating, elimination of cardiovascular and vegetatively nervous disorders and the relief of adrenal failure. The patient must be in the hospital.

    In severe cases, the patient is cooled, and such drugs are introduced as amidopyrin, analgin with diphedrol and other.

    Prevention of thyrotoxic crisis is primarily in timely diagnosis and proper treatment of thyrotoxicosis. Patients with thyrotoxicosis should always be refracted from any surgical interventions (unless, of course, they are not associated with the threat of life). Before the operation on the thyroid gland, a patient must pass a thorough examination and good treatment.

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