Miasthenia: Symptoms and Manifestation

Content

  • What is Miasthenia
  • What to pay attention to
  • The doctor prescribed
  • Dangerous moment


  • What is Miasthenia

    Miasthenia: Symptoms and Manifestation

    Miasthenia (Greek. «mys» - «muscle» and «Asthenes» - «weak») - this is a disease, nerves and muscles (cross-striped muscles), which is characterized by muscle weakness and pathological fatigue. It develops with difficult signal transmission «About movement» From the nerves to the muscles due to the violation of the exchange of acetylcholine (the autoimmune reaction is based on the disease).

    In the human body, which is a complex electrochemical machine, the movement is carried out with the help of muscles: cross-striped muscles (skeletal muscles) work in the limbs), in the internal organs and vessels - smooth muscles. The signal for the first is supplied through the motor nerves, at the site of the nerve attachment to the muscle (terminal plate), the electrical pulse is transmitted using a chemical (mediator) - acetylcholine, which moves from the nerve into the slot between the nerve and the muscle (synaptic slit), its appearance in the gap Causes electric discharge and abbreviation (work) muscles. Next, acetylcholine is split off with a special enzyme (hollynesterase) into two parts, they are inversely absorbed into the nerve, there are connected and can be used again.

    In myasthenia, a complex system of synthesis, accumulation, an acetylcholine emission, the destruction of it, the new suction - is broken, and then the next impulse is more difficult to go to the muscle, and therefore every subsequent movement is given with difficulty and finally ceases.

    This condition is called pathological syndrome (that is, abnormal) muscle fatigue. She increases in the evening, and the patients initially explain their state with ordinary fatigue after a busy labor day: in the eyes two, the eyelids stick out, the hands-legs are wadded - not to tear off the ground. Even a cup of coffee of such a fortress does not bring relief that in other circumstances of the dead from the grave would be raised, and the warm shower does not wash off fatigue, but makes perfect ruins. After all, everything is warm - water, air or sun rays - during myasthenia is contraindicated!


    What to pay attention to

    So, most often the disease begins with lowering the eyelids (at first 40%, and in the future, 85% of patients) and doubles in their eyes in the evening, then the change in voice is joined in the evening or after a long speech load (bulbar symptoms). Next, the patients note that in the morning they feel good, but putting and after performing the morning toilet, already tired as if it worked out. In the cold time, well-being is improved, worsening in warmth. Forces after rest are restored as quickly as they disappear. The disease can flow for years unrecognized, but it progresses, and sooner or later makes itself felt, but maybe too late to take something against her.

    The fact is that breathing muscles also work «on acetylcholine», and perhaps such a formidable complication of the flow of miasthenia, as a violation (stop) of breathing, when the patient can kill.

    Children's (neonatal) myasthenia (12% of newborns) requires attention to himself. Parents should not neglect the complaints of children, for example, that they cannot enter the bus or the fact that a child who goes normally, can not rotate bike pedals. Such children often become the subject of discontent and accusations of adults in «Leni», Close, cease to complain until the disorders of the movement will not be explicit for all. And the most dangerous is that children are generalization of the process - a sharp increase in respiratory failure, develops suddenly.

    Stresses, infection, intoxication (from alcohol abuse to harmful emissions into the atmosphere), physical overload and passion to fry on the sun literally before you drop the role of a trigger player, especially if the family has already had cases of this disease. A sense of action and a healthy lifestyle reduce the risk of acquaintance with Miastenia.


    The doctor prescribed

    Miasthenia usually chooses their victims among young people - from 20 to 40 years old, and women are 2-3 times more often than men. But after 50 years old chances of strong and weak gender «earn» Pseudo-Parables are equalized.

    Miastenia patient can not give a single medicine without consulting with the doctor! But spiritual peace, reasonable physical exertion, hardening and rejection of bad habits (from alcohol first, considering that Gin and Tonic contains quinine) - just that the doctor prescribed.

    A diet rich in vitamins of fresh vegetables and fruits, generous to Potassy by Kuragya and raisins and a traditional source of calcium - cottage cheese, is also important, since it reduces the severity of muscle weakness (paresis), which enhances with serial movements, and it can manifest itself in the muscles that did not participate in them: for example, after compressing and squeezing, the brush suddenly woves the pouring lead weight. This is a characteristic sign of myasthenia.


    Dangerous moment

    Approximately 10% of patients with myasthenia arises life-threatening lesion of respiratory muscles (miasthenic crisis) - attack of common muscular weakness, when a person falls like milk, breathing and heart activities are disturbed. No artificial respiration «Mouth in Roth» and heart massage will not help. Do not lose time! Call «Ambulance»! Only a doctor who has to introduce 1 ml of a 0.05% sosmene solution in Vienna, 1 ml of a 0.05% soster solution to Vienna and a quarter of an hour to make the same injection. It is possible that hardware breathing will be required, so close to the patient's hospitalization in the resuscitation department of a multidisciplinary hospital, where he will be provided around the clock observation of a neuropathologist and surgeon.

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