What are the symptoms of the disease of Pedge? How this disease flows? The author of this article knows the answers to these questions.
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Sir Jaims Podgeset first described this disease in 1877, although he used the term «deforming osteitis», We now know that Pedge's disease is not a bone inflammation (osteite), it is very rarely ends with deformation.
The diagnosis is usually based on a combination of clinical manifestations, radiographic signs and characteristic biochemical changes. Despite the fact that the histological examination of the bone affected by the PEDGET disease is diagnostically important, bone biopsy is not needed, except in cases where the diagnosis of Pedge's disease is unclear or it is necessary to exclude osteogenic sarcoma or metastatic carcinoma.
In the majority of patients with Pingzt's disease, the course of the disease is asymptomatic, and often the diagnosis is suspected, based on the analysis of X-ray pictures made for other reasons.
The most frequent symptom of the disease of the PEDGE is the pain in the bone or joint.
Much less frequent headache, bone deformation, increase in skull sizes, fractures, leather temperature change over affected bone, hypersistolic stagnant heart failure and neuropathy as a result of infringement that cause hearing loss or other neurological disorders.
Neurological disorders are the result of the pressure of the bone on the brain and cranial nerves, infringement of the spinal nerves and the immediate pressure of the vertebrae, affected by the pebiet disease, on the spinal cord.
The deformation is usually observed in patients with a significant limitation disease. Most often skull, clavicle and long bones are deformed, and detect both an increase in sizes and atypical contours of bones.
It is assumed that the loss of hearing, headaches and progressive hyperostosis of the frontal bone, observed in Ludwig van Beethoven, were a consequence of a neglected Pedget disease.
Patients with Padiz's disease reliably more often than those who do not suffer from it, there are arthrites, fractures, primary hyperparathyroidism, osteoporosis, diseases of the thyroid gland and nephrolityiasis.
Podgety disease is fraught with many complications, among which: the deformation of bones, secondary arthritis next to the bone affected by the disease of PEDGET, neurological and cardiovascular complications, fractures, etc.
Despite the fact that the disease is very difficult, there are often cases of prolonged remissions after the course of effective therapy and even cases of full cure from this ailment.
