The concept of chronic atrophic gastritis
Gastritis Chronic atrophic gastritis is, at which the significant decrease in the gastric mucous layer.
Causes of chronic atrophicgastritis is not yet fully established. It is believed that the development of such necessary gastritis triggering damage to the mucous membrane of the stomach, which may occur when the usual overeating, eating spicy or acidic foods, roughage, and under the influence of other factors. After the initial mucosal damage triggered hereditary mechanism of autoimmune processes.
Atrophic chronic gastritis accompanied bydeficiency in the immune system. This lack of production secretory immunoglobulin A. Moreover, the antibodies generated to specific cells of the stomach, which produce hydrochloric acid gastromukoproteinu antibody (Kastla factor) is the main component of the protective barrier of the stomach. The antibodies destroy the cells of the gastric glands. As a result, there is atrophy of the gastric mucosa.
Symptoms of chronic atrophic gastritis
Home atrophic process takes place in theparts of gastric parietal cells are concentrated. This is the body and fundus of the stomach. The defeat of these cells leads to a sharp decrease in the secretion of hydrochloric acid, pepsinogen, gastromukoproteina - key enzymes. Which is involved in the process of digestion. Gastromukoprotein responsible also for the absorption of vitamin B12 in the stomach. As a result of reducing its quantity in the stomach vitamin B12 absorption decreases and develops B12-deficiency anemia.
Patients with atrophic chronic gastritisThey complain of heaviness in the stomach, gastric overflow after meals. Pain in the stomach are much rarer. After the meal, there is belching air over time in regurgitation appears bitter or stale taste. Heartburn occurs. The appetite of the patient is gradually reduced, and in severe mucosal atrophy and reduced secretory function of the stomach, significant weight loss may occur. worried rumbling, gurgling in the abdomen may occur constipation, diarrhea alternated the part of the patient's bowel. Sometimes after a meal can occur weakness, sweating, dizziness.
With impaired absorption over timestomach and intestine various nutrients needed by the body. Develops dry skin and impaired vision due to vitamin A deficiency, pallor due to anemia. Lack of vitamin C can cause the occurrence of bleeding gums. There is a growing loss of hair, nails become brittle.
Diagnosis and treatment of diseases
The diagnosis of atrophic gastritis was set atmeans of X-ray (X-ray of the stomach), gastropically (fibrogastroduadenoskopiya), histological studies. A study of the functional state of the stomach - gastric intubation, intragastric pH-meter. Appointed immunological blood tests.
Treatment of chronic atrophic gastritis have to be assigned to the individual and taking into account the stage of the disease, the state of the secretory function of the stomach.
The first patient is recommendedproper nutrition. During an exacerbation assigned a diet with mechanical, thermal and chemical sparing of mucous. Food should be chopped, without coarse fibers, steamed. Hot and cold meals are excluded. The food is recommended to take in the form of heat.
Excluded and irritate the stomachproducts - sour, spicy, fried, smoked, salted. Not allowed to use carbonated and alcoholic beverages, digestible carbohydrates (sweets, cakes, chocolate), spices, sauces, pickles, canned food. Preference is given boiled meat and fish, porridge, thick soups on loosely broth nonacidic dairy products, vegetables and fruits in boiled form. In the form of a drink used jelly, mousses, weak tea, jelly, mineral waters, cocoa. Coffee is prohibited.
In severe pain in the stomach are appointedholinoliticheskie drugs (platifillin, gastrotsepin, metacin), antispasmodic drugs (Halidorum, papaverine, Buscopan, no-spa). In order to eliminate violations of gastric motility using Reglan, motilium.
If atrophic processes in the stomach led tocomplete absence of hydrochloric acid and pepsinogen, appointed replacement therapy - natural gastric juice, pepsidil, acidin-pepsin, abomin. Used panzinorm, mezim, Creon, pankurmen. Occasionally these drugs the patient has to apply for life. Appointed by vitamin supplements. In the case of anemia necessarily apply vitamin B12 and folic acid. The patient is recommended spa treatment in sanatoria gastroenterological profile.