Interstitial nephritis in children

Content


Interstitial nephritis in children
Jade -
common form of kidney disease is considered as acquired or children
hereditary process and usually affects both kidneys. In this disease the change of the stroma
kidney tubules and blood vessels occurs both independently and as a result
Some diseases, such as angina, acute respiratory viral infection, cytomegalovirus infection.

aseptic
inflammation of the kidney structures can develop and manifest itself at any age,
even in newborn infants. Among the risk factors for the disease
weighed down by history must be mentioned, allergic diathesis, dysplasia
kidney, infectious factor, poisoning with salts of heavy metals and chemicals
substances. Further causes may be the introduction of serums and vaccines,
drug intoxication with prolonged use of antibiotics,
sulfonamides, nonsteroidal anti-inflammatory drugs and analgesics.

Acute interstitial nephritis in
Toddler is a severe kidney
response to certain drugs or infections. The pathogenesis of the disease has not been studied before
the end, only one thing is clear: nephritis develops as a result of inflammation and immune
allergic process in the interstitium, resulting in a narrowing of ducts and
vessels, increased pressure in the glomeruli. A similar form of the disease tend to sharp
beginning at which develops reflex spasm of vessels, renal ischemia
tissue, accompanied by a decrease in blood flow.

first
signs of interstitial
nephritis in children whose symptoms should alert attentive
parents, this drowsiness and lethargy, as well as pain in the lumbar region,
a marked loss of appetite, and sometimes showed a slight increase
blood pressure, uncharacteristic children. Laboratory analysis of blood and urine tests reveal
increased allocation of sodium and potassium with a decrease in specific gravity
urine.

differential
diagnosis is acute glomerulonephritis characterized by edema,
hypertension and severe hematuria. Acute interstitial nephritis is not
characteristic X-ray data, there is no bacteriuria, and unlike
pyelonephritis seeding sterile urine.

The child is in
this time is recommended bed rest and mandatory removal of the drug, which has become
possible cause inflammation. Appointment of antioxidant and anti-histamines
drugs, appropriate therapy aimed at improving
the patient will quickly lead to a decrease in the performance of all the doctor's recommendations and
disappearance of interstitial edema and improvement of metabolic processes in the kidney. greater
role in the care and treatment regime belongs to a caring mother, who
It should strictly abide by all the requirements of specialist nephrologist, urologist and
pediatrician.

Risk factors for chronic interstitial nephritis in children

Interstitial nephritis in children
chronic
form of the disease is more common than acute, it has a long latency
period and is usually diagnosed by chance in the investigation of urine or
child registration in an institution. Among the predisposing factors
it should be noted anomalies of the urinary system, changes in renal hemodynamics and
urodynamics, metabolic disorders, various infections, long term administration
drugs that have a toxic effect on the kidney tissue.
Pathological process develops on the basis of progressive multiple sclerosis
interstitial, tubular atrophy with degeneration of its epithelium. As the
disease there is a weakness, pain in the abdomen and in the lumbar region. Nephritis
It progresses slowly, but steadily, and can occur in future years
strengthen the kidney's inability to normal concentration of urine. growing loss
calcium, muscle weakness, osteodystrophy, salt depletion, may
manifest syndrome "solteryayuschey kidney" noticeable child stunting,
develop a picture similar to kidney failure.

Treatment
It suggests diet and correction of metabolic disorders, with a mandatory exception
products that contribute to irritation tubules, conducting medical
treatment, protection from hypothermia and physical activity. With careful implementation of
all the doctor's instructions, a favorable outcome occurs within 3-4 months.

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