joint infections there, it affects the genitourinary system or
gastrointestinal tract. However, it affects the joints. Infection
It appears a "trigger" that disrupts the immune
system, and it is the latest "attack" on the joints. Therefore, even
eliminating infections with antibiotics is not always helpful
get rid of the problems.
The term "reactive arthritis" (ie, joint inflammation,
which occurs as a reaction in response to an infection elsewhere) was
Anhovenom proposed in 1969. It is interesting that until recently
the disease was named after German physician Hans Reiter (which first
He described this combination of symptoms), but the latter was a supporter
Nazis and eugenics, participated in human experiments
concentration camps. So now the preference is given to the term is
Reiter's syndrome, Reiter's syndrome symptoms
Reactive arthritis (Reiter's syndrome) - inflammatory
joint disease that develops after infection (no joint,
and in another part of the body). Infections caused by reactive development
arthritis usually affects the urinary tract or gastrointestinal
Reactive arthritis is not associated with the spread of infection by
the body and its release to the joint. It is believed that inflammation
joint develops due to the fact that the microorganisms contain substances
(Antigens), which are similar to antigens of the body's tissues. immune
system "confuses" the joint antigens and microorganisms, as a result of it
and microbe attacks and joint. The joint inflammation develops which
and it causes problems.
Three classic symptoms of reactive arthritis: inflammation of the eye (conjunctivitis - eye redness, burning sensation in the eyes, watery eyes), inflammation of the urinary tract (urethritis -
pain or burning with urination, frequent urination) and
inflammation of the joints (arthritis - joint pain, their redness, swelling,
hot joints, the mobility is limited).
Reactive arthritis usually begins 2-4 weeks after
intestinal or venereal infection. The most common first symptom is
urethritis, conjunctivitis then developed, and the last - arthritis.
Approximately every fourth patient has skin changes
The symptoms of reactive arthritis is usually stored from three to
twelve months. In most cases, symptoms and conjunctivitis
urethritis expressed very poorly and only 1-2 inflamed joint. some
Patients, however, reactive arthritis can be acute and severe,
limit their physical activity.
Relapses (repeated exacerbations) are rare.
Causes Reiter's syndrome
Most often, reactive arthritis associated with microorganisms,
called chlamydia. Hladimii usually transmitted through sexual
contacts. Often the infection has no symptoms, but the most frequent
symptoms (if present) - pain or discomfort when
urination and discharge from the penis or vagina.
In addition, reactive arthritis can cause bacteria
affecting the gastrointestinal tract: Salmonella, Shigella, Yersinia and
campylobacter. Symptoms of gastrointestinal tract
They are severe diarrhea with blood and mucus in the stool. Infection
It is due to the wrong receiving cooked food, in contact with
with infected people or fecal (microorganism should get in
Reactive arthritis develops not all people after
Moved infection. The reasons for this are unclear selectivity. It is shown
disease that often develops in people who have a special gene - HLA B
27 (Al-Al-Be-A 27).
Reactive arthritis most often affects people between the ages
20-40. Interestingly, after infections, sexually transmitted infections,
ill men nine times more often than women, while after
intestinal infections, the risk of the same. Men suffer more
Diagnosis of Reiter's syndrome
Simple and straightforward test that allows to establish the diagnosis
reactive arthritis does not exist yet. A doctor may suspect that
the diagnosis of the patient with proper questioning and examination and then
appoint a special study to confirm it.
- On examination, special attention is paid to the detection of signs of joint damage, eyes, urinary tract, skin.
research is needed for two reasons: to confirm the diagnosis
reactive arthritis and to exclude other causes of arthritis.
Arthritis is often increased erythrocyte sedimentation rate (ESR) and the content
C-reactive protein (CRP); These tests indicate the presence of
inflammation of the body.
- Research on rheumatoid factor (RF) and antinuclear factor (ANF) with reactive arthritis are negative.
- Detection of HLA 27 - argument in favor of reactive arthritis.
to infection (chlamydia, yersinia and others.) has a large value,
because it allows you to discover the probable cause of the disease. explore
may discharge from the genital tract, blood, stool, etc..
exclude joint infection (bacterial arthritis) is sometimes performed
joint puncture and examined him taken out of the fluid (synovial
- X-rays can
used to assess the condition of the joint, but definitely set
cause joint inflammation, it allows infrequently.
Reiter's Syndrome Treatment
Treatment for reactive arthritis predominantly directed at relieving symptoms.
If signs of active infection persist, then appointment is justified
antibiotics to eliminate bacteria and to remove the root cause of the inflammation.
Nonsteroidal anti-inflammatory drugs (such as ibuprofen,
diclofenac, indomethacin, etc.) reduces the pain and inflammation of the joints.
In severe inflammation of the joints sometimes perform injection in these glucocorticoids (anti-hormones).
With long-term preservation of joint pain appoint
anti-inflammatory drugs, which slow down the damage to the joint - sulfasalazine, methotrexate, and others.
During active inflammation joint should be protected from stress.
However, after his relief recommended a gradual recovery