What is Reiter's syndrome

Content

  • Reiter's syndrome, Reiter's syndrome symptoms
  • Causes Reiter's syndrome
  • Diagnosis of Reiter's syndrome
  • Reiter's Syndrome Treatment

  • Many human diseases are associated with an infection, but not directly. A striking example - reactive arthritis (Reiter's syndrome).
    joint infections there, it affects the genitourinary system or
    gastrointestinal tract. However, it affects the joints. Infection
    It appears a "trigger" that disrupts the immune
    system, and it is the latest "attack" on the joints. Therefore, even
    eliminating infections with antibiotics is not always helpful
    get rid of the problems.

    The term "reactive arthritis" (ie, joint inflammation,
    which occurs as a reaction in response to an infection elsewhere) was
    Anhovenom proposed in 1969. It is interesting that until recently
    the disease was named after German physician Hans Reiter (which first
    He described this combination of symptoms), but the latter was a supporter
    Nazis and eugenics, participated in human experiments
    concentration camps. So now the preference is given to the term is
    "Reactive arthritis."



    Reiter's syndrome, Reiter's syndrome symptoms

    Reactive arthritis (Reiter's syndrome) - inflammatory
    joint disease that develops after infection (no joint,
    and in another part of the body). Infections caused by reactive development
    arthritis usually affects the urinary tract or gastrointestinal
    tract.

    What is Reiter's syndrome
    Reactive arthritis is not associated with the spread of infection by
    the body and its release to the joint. It is believed that inflammation
    joint develops due to the fact that the microorganisms contain substances
    (Antigens), which are similar to antigens of the body's tissues. immune
    system "confuses" the joint antigens and microorganisms, as a result of it
    and microbe attacks and joint. The joint inflammation develops which
    and it causes problems.

    Three classic symptoms of reactive arthritis: inflammation of the eye (conjunctivitis - eye redness, burning sensation in the eyes, watery eyes), inflammation of the urinary tract (urethritis -
    pain or burning with urination, frequent urination) and
    inflammation of the joints (arthritis - joint pain, their redness, swelling,
    hot joints, the mobility is limited).

    Reactive arthritis usually begins 2-4 weeks after
    intestinal or venereal infection. The most common first symptom is
    urethritis, conjunctivitis then developed, and the last - arthritis.
    Approximately every fourth patient has skin changes
    different appearance.

    The symptoms of reactive arthritis is usually stored from three to
    twelve months. In most cases, symptoms and conjunctivitis
    urethritis expressed very poorly and only 1-2 inflamed joint. some
    Patients, however, reactive arthritis can be acute and severe,
    limit their physical activity.

    Relapses (repeated exacerbations) are rare.



    Causes Reiter's syndrome

    Most often, reactive arthritis associated with microorganisms,
    called chlamydia. Hladimii usually transmitted through sexual
    contacts. Often the infection has no symptoms, but the most frequent
    symptoms (if present) - pain or discomfort when
    urination and discharge from the penis or vagina.

    In addition, reactive arthritis can cause bacteria
    affecting the gastrointestinal tract: Salmonella, Shigella, Yersinia and
    campylobacter. Symptoms of gastrointestinal tract
    They are severe diarrhea with blood and mucus in the stool. Infection
    It is due to the wrong receiving cooked food, in contact with
    with infected people or fecal (microorganism should get in
    gastrointestinal tract).

    Reactive arthritis develops not all people after
    Moved infection. The reasons for this are unclear selectivity. It is shown
    disease that often develops in people who have a special gene - HLA B
    27 (Al-Al-Be-A 27).

    Reactive arthritis most often affects people between the ages
    20-40. Interestingly, after infections, sexually transmitted infections,
    ill men nine times more often than women, while after
    intestinal infections, the risk of the same. Men suffer more
    heavier women.



    Diagnosis of Reiter's syndrome

    Simple and straightforward test that allows to establish the diagnosis
    reactive arthritis does not exist yet. A doctor may suspect that
    the diagnosis of the patient with proper questioning and examination and then
    appoint a special study to confirm it.

    • On examination, special attention is paid to the detection of signs of joint damage, eyes, urinary tract, skin.
    • special
      research is needed for two reasons: to confirm the diagnosis
      reactive arthritis and to exclude other causes of arthritis.
    • at
      Arthritis is often increased erythrocyte sedimentation rate (ESR) and the content
      C-reactive protein (CRP); These tests indicate the presence of
      inflammation of the body.
    • Research on rheumatoid factor (RF) and antinuclear factor (ANF) with reactive arthritis are negative.
    • Detection of HLA 27 - argument in favor of reactive arthritis.
    • research
      to infection (chlamydia, yersinia and others.) has a large value,
      because it allows you to discover the probable cause of the disease. explore
      may discharge from the genital tract, blood, stool, etc..
    • For
      exclude joint infection (bacterial arthritis) is sometimes performed
      joint puncture and examined him taken out of the fluid (synovial
      liquid).
    • X-rays can
      used to assess the condition of the joint, but definitely set
      cause joint inflammation, it allows infrequently.



    Reiter's Syndrome Treatment

    Treatment for reactive arthritis predominantly directed at relieving symptoms.

    If signs of active infection persist, then appointment is justified
    antibiotics to eliminate bacteria and to remove the root cause of the inflammation.

    Nonsteroidal anti-inflammatory drugs (such as ibuprofen,
    diclofenac, indomethacin, etc.) reduces the pain and inflammation of the joints.

    In severe inflammation of the joints sometimes perform injection in these glucocorticoids (anti-hormones).

    With long-term preservation of joint pain appoint
    anti-inflammatory drugs, which slow down the damage to the joint - sulfasalazine, methotrexate, and others.

    During active inflammation joint should be protected from stress.
    However, after his relief recommended a gradual recovery
    physical activity.

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