Life extension issues have always worried about the minds of people. Searches «Medicines from old age» Estimation of the centuries were engaged in alchemists, shamans, priests. How are things today, and whether modern scientists managed to approach the cherished goal - to create «Tablets from old age»?
Content
- In search of medicine from old age
- Want to live long — Remove the thick intestine!
- Low-calorie diet as a medicine from old age
Life extension issues have always worried about the minds of people. Searches «Medicines from old age» Estimation of the centuries were engaged in alchemists, shamans, priests. How are things today, and whether modern scientists managed to approach the cherished goal — Creation «Tablets from old age»?
In search of medicine from old age
Life extension issues have always worried about the minds of people. Searches for the elixir of the immortality of time immemorials were engaged in alchemists, shamans, priests, and must be said which — they successfully achieved, however, we did not have a chance to learn about them, the secrets of eternal youth of the magicians were usually carried away with them to the grave. So it lasted until gerontology was born in the twentieth century — Science, which is engaged in the study of all aspects of human aging, reasons, analysis of mechanisms for wilting and finding funds for rejuvenation and extension of life by increasing the duration of its active period.
Want to live long — Remove the thick intestine!
The founder of gerontology is the Russian scientist Ilya Mesnikov, who suggested that the cause of human aging is a detrimental effect of microorganisms living in the intestine. Swords believed that having got rid of «parasites», inhabiting the digestive tract, thereby stopping the grinding processes in the body, can be extended life for many years. He offered to drink more kefir, and for the best effect — Delete a fat intestine, one felling to get rid of his flora. Today we already know how important this flora is for a person, but in those days the views of the scientist seemed very progressive.
More than a hundred years have passed and during this time humanity has accumulated a lot of knowledge in the field of medicine, biology, genetics, biochemistry. The information obtained turned out to be enough to begin serious work on the creation of a longevity elixir, capable of bringing the lifespan of a person to a species maximum of 120-130 years.
Low-calorie diet as a medicine from old age
«Who eats little, lives long, for a spoon and fork, we grave yourself» — said not essential Count Caliostro from the story of the same name A.Tolstoy. In fact, the only effective scientific way to extend the life is a low-calorie diet. Experiments conducted on mice, yeast, nematodes, flies-drosophilas, allowed to identify not only the biochemical mechanisms of relative starvation as an elixir longevity. As a result of scientific searches, substances acting as «Tablets from old age».
In 2009, American researchers recorded that the drug Rapamycin, used as an immunosuppressor for the prevention of rejection of the implantated organs and tissues, has an amazing effect on experimental animals. Mice receiving medicine live longer than their deprived relatives on average by 9-13%, and Rapamycin does not just lengtheys life, he «Lechit» Elder diseases. It would seem that the recipe for youth was found, however, the active suppression of immunity would make a person defenseless before infections and abruptly would increase the incidence of cancer. And although it is impossible to use rapamycin to extend the life, the mechanisms of its influence on aging processes were appreciated. It turned out that these mechanisms are similar to those with low-caloride nutrition, that is, in the future you can create «Tablets from old age», which would act like a diet, but at the same time they did not force a person to starve.
Glass of Wine gives youth and health!
The question of why the French leading is not such a healthy lifestyle, the least suffer from atherosclerosis and less often die from cardiovascular — Vascular diseases, long ago worried about the minds of physicians, because heart disease and vessels are in the first place among the causes of death. The explanation was found in 1992, when Serge Reno and Michel de Lorgeryl published research results, suggesting that the high life expectancy of the French is connected with their love for red guilt.
In the bone and peel of the red grapes, a resveratrop flavonoid was found, which possesses a powerful antioxidant effect, capable of protecting the cells of the body from damage to their free radicals. The fact that the main cause of aging is the peroxidation oxidation of lipids membranes known for a long time. It has been proven that resveratrop is capable of activating Sirtuin synthesis — Proteins activating «Work» genes and protein synthesis, that is, impeding aging. The mechanism of action of this «Tablets from old age» It was similar to action «Hungry» diet, but in contrast to rapamycin, immunity suppression was not observed.
Since resveratop in wine contains little to feel the rejuvenating effect. It needs to drink up to 2 liters per day. But Perspective «One sip» Fill an aging body with a lifeful force left the minds of people. Markets filled bades based on concentrates from winemaking waste, although no clinical trials were conducted and, it is likely that Resveratro has some side effects. Now test substances go full.
In 2007, other synthetic stimulants were found under the SRT1720, SRT2183 and SRT1460 codes, which were much more efficient, rather than resveratrop. Some of them also come to check, but not like «Tablets from old age», And as medicines from diabetes and cancer.
SRT1720 substance and gives high hopes. It turned out that when he was introduced into the body, in mice, despite the elevated appetite, there is no set of body weight, cholesterol is reduced, blood sugar is normalized. Dream of many — there is plenty, and at the same time stay in a magnificent physical form, it turned out to be not such a transcendental.
Attempts to obtain Elixir longevity led many scientists in various directions. Considered the fact that aging and death — This is a necessary evolutionary process necessary for humanity, and the fact that its cause is free radicals, and the fact that it is possible to move old age, extending telomerase chromosomes or raising stem cells. Under the guidance of academician in.NS. Skulachev developed preparations based on substances delivering antioxidants inside cells neutralizing free radicals, thereby extending life and improving its quality.
Thanks to the works carried out, conclusions were made that old age — This is the voluntary death of the cells, the cause is the change in the activity of genes, which means that the adjustment of this activity is able to solve the problem of longevity. True, assume what is fraught with human intervention in the work of genes is quite difficult, and whether the extension of the life of such victims is.
