Blood on the human chorionic gonadotropin (hCG) in pregnancy
Human chorionic gonadotropin - a hormone innormally synthesized only during pregnancy fetal membranes, and then the placenta. The level of hCG in the blood of women begins to rise from the time of embryo implantation in the uterus.
Functions of Human Chorionic Gonadotropin:
- stimulation of the synthesis of progesterone and estrogen in the ovaries;
- the maintenance and continuation of the pregnancy;
- prolactin blocks together with the menstrual cycle.
HCG levels at different stages of pregnancy may serve as diagnostic criteria of a particular disease or condition. on the study provides a gynecologist direction.
Interpretation of the results of the analysis on the hCG Pregnancy
On the first day of pregnancy, hCG levels in the bloodgrowing, reaching a peak in 11-12 weeks. After this period it gradually decreases, reaching a minimum at the time of delivery. Units - U / L or mU / mL.
The rate of hCG during pregnancy:
- for 4 weeks from conception - 10,000-30,000 IU / ml;
- 11-12 weeks - 20000-225000 mIU / mL;
- 17-18 weeks - 8000-57000 IU / ml;
- 20-28 weeks - 1600-49000 IU / ml.
Increased hCG levels during pregnancy above reference values observed in these pathologies and conditions:
- fetal abnormalities, chromosomal disorders (Down syndrome, Edwards);
- maternal diabetes;
- pronounced early toxicosis;
- multiple pregnancy.
Hormonal agents (progestogens) stimulates the synthesis of hCG.
Reduced levels of hCG below the norm - a sign of the following pathologies:
- intrauterine fetal death in late pregnancy;
- developing pregnancy in the early stages;
- ectopic pregnancy;
- threatening spontaneous abortion;
- fetoplacental insufficiency;
- prolonged pregnancy.