About leukocytes and leukopenia

Content

  • When there is leucopenia
  • The types of leukocytes and their causes low blood
  • Manifestations of leukopenia
  • Fight with leukopenia


  • When there is leucopenia

    About leukocytes and leukopeniaLeukopenia is expressed in deficiency of granulocytes or lymphocytes.

    Reducing the number of granulocytes can be observed inany age and lead to infection and inflammation in the throat, digestive tract, to the defeat of the mucous membranes and skin.

    Reduction in the number of lymphocytes, which are formed mainly in lymph nodes, is rare.

    When the content of leukocytes in the blood drops toa dangerous level, the body becomes defenseless against infections. The prognosis depends on the cause of the decrease in the number of white blood cells, and the possibility of its removal.

    These reasons include (leukopenia often develops as a complication of some diseases):

    • Infection;
    • Sepsis;
    • Viral and fungal infections;
    • Protozoal infections (falciparum malaria).

    Gynecological complications

    • Amniotic embolism;
    • Placental abruption;
    • Unreleased dead fetus;
    • Sepsis, which developed as a result of abortion;
    • Eclampsia.

    Oncological diseases

    • Acute leukemia;
    • Cancer being circulated.

    Diseases that cause necrosis (necrosis) of tissue

    • Extensive burns and injuries;
    • Destruction (violation of the structure) tissue of the brain;
    • Transplant rejection;
    • Necrosis of the liver.

    Other reasons

    • The attack of angina pectoris;
    • Shock;
    • Snakebite;
    • Cirrhosis of the liver;
    • Fat embolism;
    • The transfusion of incompatible blood;
    • Heart failure;
    • The surgery using cardiopulmonary bypass;
    • Hemorrhagic cyst;
    • Dangerous blood clot in the vein.


    The types of leukocytes and their causes low blood

    About leukocytes and leukopeniaBlood contains five types of white blood cells, whose purpose - to protect the body from bacteria. All types of white blood cells are divided into two categories: granulocytes and agranulocytes.

    Granulocytes

    For cytoplasm (cellular material) of the white blood cells characterized by grain. There are three types of granulocytes: basophils, neutrophils and eosinophils.

    The low concentration of granulocytes can be caused by the following reasons:

    • radiation therapy, or anticancer drugs;
    • increased susceptibility to certain antibiotics and cordial agents;
    • a number of diseases (such as anemia, bone marrow cancer, certain inherited diseases, infectious mononucleosis, viral and bacterial infections);
    • Taking of blood cells of the spleen.

    agranulocytes

    In the cytoplasm of leukocytes is not grainy. Two types agranulocytes: lymphocytes and monocytes.

    The reasons for low levels of lymphocytes:

    • genetic abnormalities;
    • radiation therapy or anticancer drugs;
    • dysfunction of the lymphatic bowel vessels;
    • steroid hormone excess resulting from the use of steroids or adrenocorticotropic hormone, stress, or congestive heart failure;
    • serious illness (eg, diseaseHodgkin's, leukemia, aplastic anemia, sarcoidosis, myasthenia gravis, systemic lupus erythematosus, the lack of protein in the diet, kidney failure, cancer and tuberculosis).


    Manifestations of leukopenia

    The low concentration of granulocytes usually causesthe gradual weakening of the body. As a result of rapidly developing infection (symptoms: fever, chills, rapid heartbeat, restlessness, headaches, exhaustion of the whole body), inflammation of the mouth, sores in the colon, pneumonia and blood infection, which can cause a weak shock. If the lowering of the content of leukocytes caused by a reaction to certain medications, symptoms are increasing rapidly.

    Low content of lymphocytes characterized by swollen glands, enlarged spleen, enlarged tonsils, as well as symptoms of diseases have joined.


    Fight with leukopenia

    Diagnosis is based on medical history,inspection, during which the doctor is trying to find signs of the root causes of leukopenia; besides blood tests performed bone marrow and lymph node biopsy, if necessary.

    Treatment is aimed at removing or correctingthe root causes that led to a decrease in the content of white blood cells, so the doctor has to establish and, if possible, eliminate the cause of the violation, as well as slow down the spread of infection. Many patients cancel medications and radiation therapy and start treatment with antibiotics before the results of many tests. Can be administered antifungal drugs. Recently, drugs used to stimulate bone marrow production of neutrophils. Usually within 1-3 weeks the bone marrow spontaneously resumes production of leucocytes.

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