Let's talk about what isthis drug and in what cases it is advisable to apply it. Read the instructions carefully - suddenly in the next time you have to apply this knowledge in practice?
Ortofen - a non-steroidal drug witha pronounced anti-inflammatory effect. In addition, the drug has analgesic and antipyretic effect. Ortofen belongs to the category of synthetic drugs and has several pharmaceutical forms. On the shelves of pharmacies you can see dragees, suppositories, solution, tablet, ointment and gel with the same name.
Current Ortophenum substance - sodium diclofenac.
1 tablet contains medicament25 mg of the active ingredient. The amount of diclofenac in 1 ampoule Ortophenum reaches 75 mg. 100 g of gel antiinflammatory drug saturated 5 g of active ingredient.
Features of the drug
The main specific feature is Ortophenuminhibiting cyclooxygenase activity, or COX. This is the main enzyme derived arachidonic acid, which is inherently related prostaglandins - instigators of the inflammatory response, pain and heat.
Pain attack Ortofen relieves, starting atthe body peripheral and central mechanisms. The mechanism is based on the peripheral-mediated inhibition of prostaglandin production, but the principle is the central mechanism inhibiting the synthesis of prostaglandins in central and peripheral nervous system.
Due to such effects on the body Ortofensignificantly reduces pain caused by rheumatic diseases, eliminates swelling of joints in the morning, prevents stiffness and generally helps to build physical activity. Useful drug in emergency situations: diclofenac copes with post-traumatic and post-operative pain, reduces inflammatory swelling.
Once in the body, the active substances of Ortophenquickly absorbed from the digestive tract and spread throughout the body. The absorption rate slows down somewhat as a result of eating, but the degree of absorption of the drug remains unchanged. Almost half of the active components of the drug are broken down immediately after penetration into the liver. The maximum concentration of Orthofen in the blood is observed after 2–4 hours after administration. Time varies depending on the form of the drug. About 60% of a single dose in a split form is excreted by the kidneys, less than 1% is excreted unchanged in the urine, the rest of the split part of the drug is excreted in the bile.
In some cases, you can take the drug
mymedinform.com hastens to inform its readers, in what situations it is impossible to take Ortofen:
- Gastrointestinal disease in the acute form.
- Children under 6 years of age.
- Pregnancy and breast-feeding.
- Severe disorders of the liver and kidneys.
- High sensitivity to nonsteroidal anti-inflammatory drugs and aspirin.
- Propensity to allergic reactions.
Features of the drug
- Ortofen prescribed with great caution, if the history of the patient appear kidney or liver disease, disorders of the gastrointestinal tract, bronchial asthma or heart failure.
- By a special risk group includes people operated on recently, and elderly patients.
- During treatment, the patient must be systematically ortofenom pass liver and kidney examination, as well as for tests on peripheral blood.
- Rectal Suppositories Ortofen contraindicated if the patient suffers or suffered from disease in the past, a place where localization is the anorectal region.
- During treatment ortofenom can not drink alcohol.
- After the drug is observed inhibition of psychomotor reactions. This means that the treatment machine ortofenom led undesirable.
Drugs similar ortofenom
There is a list of drugs that can be successfully replaced Ortofen:
- Voltaren Emulgel;
- Rapten Duo;