Hyperprolactinemia: Treatment and Diagnosis

Content


This disease
young women, occurring between the ages of 25-40 years, can be observed in 40-50%
of cases of infertility in 10-20% with amenorrhea, often after childbirth or abortion. what
can become a cause of hyperprolactinemia in a young healthy body?
The answer to this question should be sought from specialists: endocrinologists,
gynecologists, mammologists, ophthalmologists and general practitioners. The causes can be divided into
4 groups.

Hyperprolactinemia: Treatment and Diagnosis
  • The first group of causes of hyperprolactinemia in women should include chronic infectious diseases of the brain, such as
    meningitis, encephalitis, as well as traumatic injuries, which have a negative
    effects on the hypothalamus.
  • The second group is characterized by impaired
    pituitary functions in connection with the occurrence of tumors of various etiologies,
    syndrome of "empty sella" in which the X-ray diagnostics provides
    picture of degenerative changes in the pituitary gland.
  • In some cases, the overproduction of prolactin
    provokes hypothyroidism - low thyroid function syndrome
    Polycystic ovarian hormone dependent pathology of genitals - myoma
    uterus, endometriosis and chronic hepatitis, herpes zoster or progressive
    renal insufficiency.
  • Often young women are different unreserved
    affection to the reception of various drugs having a side
    effect as an increase in prolactin levels, it is the fourth group of reasons -
    contraceptives, antidepressants, drugs with a high content of estrogen.


Features women with hyperprolactinemia

before
all, it should be noted that the outwardly women do not differ from gipeprolaktinemiey
from healthy peers. The symptoms of the disease manifest themselves in the form of:

  • menstrual cycle - lack of
    luteal phase, lack of ovulation, oligomenorrhea, amenorrhea;
  • infertility;
  • Galactorrhea - abnormal discharge of milk from nursing infants
    glands;
  • frigidity and decreased libido;
  • hirsutism - hair growth in male pattern;
  • Acne - inflammation of the sebaceous glands;
  • metabolic and metabolic problems - osteoporosis,
    obesity, hyperinsulinemia, various psycho-emotional disorders.

Besides
allocated primary symptoms of hyperprolactinemia, when the fore
perform all of the above symptoms. As the process progresses
joins hypoplasia of the genital organs, marked them dry with difficulty
sexual intercourse, lack of orgasm, hypertrichosis. Clinical manifestations of secondary
hyperprolactinemia defined symptoms of the underlying disease.

Diagnosis of hyperprolactinemia
carried out in stages:

  • a blood test for prolactin and hormones;
  • X-rays of the skull in the "sella";
  • CT and MRI of the brain.

differential
with the syndrome diagnosis
hyperprolactinemia in women involves identifying:

  • adenoma
    pituitary;
  • prolactinoma;
  • tumor
    parasellyarnoy area;
  • bronchogenic
    cancer;
  • syndrome
    Polycystic ovary;
  • chronic
    diseases of the pelvic organs;
  • physiological
    or pharmacologically conditioned form of the disease;
  • first
    hypothyroidism;
  • cirrhosis
    liver;
  • chronic
    renal failure.


hyperprolactinemia syndrome
among women

Hyperprolactinemia: Treatment and Diagnosis

Treatment
hyperprolactinemia is usually done with the therapeutic methods
using drugs, normalizing prolactin in the blood and
reducing menstrual cycle with regard to the shape and condition of the disease
women:

  • infertility and functional
    hyperprolactinemia;
  • infertility and mikroprolaktinoma;
  • pituitary tumor;
  • gipeprolaktinemii secondary form.

Therapy
this syndrome is carried out strictly according to the testimony of dopamine stimulants
receptors and hormones. When the form of iatrogenic disease treatment
is cancellation of drugs or other harmful factors.

Surgical
intervention is rarely used, usually on the basis of recommendations of an ophthalmologist
with a significant abuse visual acuity and in the case where the effect is attained
of therapeutic treatment. Additional radiation therapy is indicated in connection with
hypothyroidism, or renal insufficiency.

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