Methods of diagnosis of autoimmune thyroiditis
Diagnosis of autoimmune thyroiditis is basedon the main symptoms and laboratory data. The presence among the other members of the family of autoimmune diseases supports the possibility of an autoimmune thyroiditis. In a laboratory study, determine the presence of antibodies to various components (thyroglobulin, peroxidase, the second colloid antigen tiroidstimuliruyuschie, tiroidingibiruyuschie, antibodies to thyroid hormone, and others.) Thyroid gland. Laboratory diagnosis of autoimmune thyroiditis also includes, in addition to determining the total and free triiodothyronine and thyroxine, determine the level of thyroid stimulating hormone in blood serum when it has no clinical symptoms and signs.
If there are major symptoms of the disease, thethe possibility of malignant degeneration of the thyroid gland (nodule development) increases significantly. For the diagnosis of fine needle biopsy is needed. Have the patient tirotoksikoza phenomena it does not exclude the possibility of malignant degeneration of the thyroid gland. Autoimmune thyroiditis is often a benign course. Extremely rare lymphoma of the thyroid gland. Sonography, or ultrasound of the thyroid gland to determine the increase or decrease its size. Similar symptoms also occur in diffuse toxic goiter, so by ultrasound can not diagnose.
Methods of treatment of autoimmune thyroiditis
Specific therapy of autoimmune thyroiditis are notexist. When thyrotoxic phase of autoimmune thyroiditis used symptomatic agents. When hypothyroidism phenomena prescribe thyroid hormone drugs, for example, L-thyroxine. Purpose thyroid drugs, particularly in the elderly, who tend to have coronary heart disease, it is necessary to start with small doses, increasing every 2.5-3 state before normalization. Monitoring of serum levels of thyroid stimulating hormone to spend no more than 1.5-2 months.
Corticosteroids (prednisone) is prescribed onlywhen combined with autoimmune thyroiditis subacute thyroiditis, which often occurs in autumn-winter period. There are cases when women suffering from autoimmune thyroiditis with symptoms of hypothyroidism during pregnancy was observed spontaneous remission. On the other hand, there is the observation that patients with autoimmune thyroiditis, which before and during the pregnancy indicated eutiroidnoe condition after childbirth evolved phenomenon of hypothyroidism.
In hypertrophic form of autoimmunethyroiditis and expressed the phenomenon of compression of mediastinal enlarged thyroid surgery is recommended. Surgery is also shown in the cases where a long time existed a moderate increase in thyroid begins to progress quickly in volume (size).
The disease tends to slowprogression. In some cases, a satisfactory state of health and working capacity of patients are stored for 15-18 years, despite the short-term aggravation. In the period of acute thyroiditis may experience minor phenomenon thyrotoxicosis or hypothyroidism; the latter is more common after childbirth.