Hypothyroid coma - this is an extreme developmentgipotiroza. It is a life-threatening complication gipotiroza. In hypothyroid coma occurs marked reduction in production of thyroid hormones (thyroxine, triiodothyronine).
The trigger mechanism is to reduceadaptive capabilities of the organism when exposed to adverse or stressful situations. At the same time due to lack of thyroid hormones violated carbohydrate, fat, protein and water-salt exchange, there is oxygen starvation of tissues, disorders in the circulatory system.
Causes of hypothyroid coma may include:
- physical injury
- mental stress
- acute infectious diseases
- the appointment of sleeping pills and anti-depressant drugs on the background of hypothyroid condition.
In these situations, there is an increased need for thyroid hormones, which can not be filled due to the reduction of its functions and develop acute deficiency of thyroid hormones.
Status hypothyroid coma usually developsgradually. At the beginning can appear drowsiness, weakness. a slight decrease in body temperature can be detected. The skin is dry, but the skin is swollen. There is a slowing of speech, sense of porridge in your mouth when speaking. Blood pressure is reduced.
In the further course of the process the body temperaturedecreases to 35 degrees or less, there is a slowing of heart rate to 30 bpm. Blood pressure drops to critical numbers. It is becoming rare and shallow breathing. On the part of the gastrointestinal tract are marked flatulence, abdominal pain, constipation, bloating. Due to lower blood pressure and reduced cardiac output, reduced kidney function and reduced urine output till its complete extinction.
Diagnosis of hypothyroid coma
The diagnosis of hypothyroid coma set atBased on the growth gipotiroza symptoms after undergoing a stressful situation for the body, lower body temperature, a sharp decline in blood pressure, drowsiness, confusion, lethargy, and loss of consciousness. The blood is determined by the low concentration of thyroid hormones.
Treatment of hypothyroid coma
Treatment is carried out under conditions of intensive caredepartment of hospital inpatient. Intravenously administered synthetic thyroid hormones (levotriyodtironin) or inside gavage iodine preparations.
Appointed synthetic cortex hormonesadrenal (hydrocortisone, prednisolone). Sometimes you have to resort to artificial ventilation. Carry out emergency measures to normalize blood pressure, heart rate, the volume of urine output, body temperature.
Prediction state depends on timelinessstarted treatment, the age of patients and the presence of concomitant diseases of the cardiovascular system, kidney, central nervous system. If untreated hypothyroid coma mortality is very high. With modern treatment 70-80% of patients recover.