Candidiasis oral mucosa


  • What is Candidiasis
  • Why there is oral candidiasis?
  • Treatment of oral candidiasis

  • What is Candidiasis

    Candidiasis (thrush), yeast-induced
    the fungus Candida albicans, manifested cheesy kind of raid on
    oral mucosa. This plaque can be easily removed, leaving
    behind the painful bleeding surface. With the progression
    the disease can be observed the spread of the sky, the gums, the palatine
    tonsil, larynx, the gastrointestinal tract.

    Acute atrophic candidiasis, caused by often
    is a long-term use of broad spectrum antibiotics, appears
    painful, bleeding, swollen reddened mucosal areas
    oral cavity and plaque curd can not be.

    Chronic atrophic candidiasis occurs
    usually those who wear dentures. It affects the mucous directly
    adjacent to the prosthesis. Most often this occurs because of the soft tissue trauma
    ill-fitting dentures, which can lead to chronic
    inflammation. The affected area of ​​reddened, swollen. Characterized by pain and burning.

    Why there is oral candidiasis?

    Microscopic fungus, often Candida albicans, is
    a normal inhabitant of the oral mucosa. However, as conditions change
    the existence of the causative agent of thrush can multiply rapidly. For
    normal operation of the mucous membranes requires a stable weakly acidic medium,
    normal microflora, necessary and sufficient amount of nutrients,
    good blood supply, regular cleansing. A different situation arises when
    changing conditions in which the yeast fungus lives. When you change the level of
    pH (or pH), the appearance of cells in a significant amount of sugar,
    or leaching beneficial flora suppression with antibiotics it at different
    infections of fungi begin to multiply rapidly. There is a loss of cells
    mucosa, develops oral candidiasis.

    Treatment of oral candidiasis

    Therefore, the main
    trends in the treatment of a patient with candidiasis are:

    • identification of the etiological factor underlying the pathogenesis of candidiasis in each individual case;
    • elimination or reduction of further negative impact of these factors;
    • pathogenetic therapy;

    Candidiasis oral mucosaBased on the failure of the immune system with candidiasis,
    especially for chronic low-intensity forms recommended candida
    vaccine: monovalent, polyvalent and autovaccine.

    With the same purpose in the arsenal of therapeutic agents for candidiasis can
    find place pyrimidine derivatives - pentoksil 0.2 grams 3 times per day
    for 3 weeks methyluracil 0.5 x 3 times a day treatment 3-4
    weeks. The drugs stimulate the production of antibodies, phagocytic
    Activity, stepping leucopoiesis, increase the content of gamma globulin
    in serum, increases the regenerative capacity of tissue.

    Gamma globulin hystoglobulin, gistaglobin 2 ml, 2 times a week,
    in the course of 7-10 injections. After 2-3 months. treatment is repeated.

    In the treatment of candidiasis of the oral mucosa is used on T-activin
    40 ug per day by subcutaneous or intramuscular injection, for 7-10 days.
    Kemantan 0.2-3 times a day, for 14 days. Either diutsifon 0.1-2 times
    per day for 6 days. Spend 2-3 such courses with an interval of 1-3
    day, under the control of biochemical and immunological parameters of blood.
    Levamisole (dekaris) 150 mg 1 time per day for 3 days, hold 2
    of course with an interval of 3-6 days. After 2-3 months of treatment is

    • restorative therapy, reduces mycotic sensitization and
      and stimulating non-specific and specific resistance
    • inclusion in the comprehensive treatment of antifungal drugs.

    In the treatment of candidiasis of the oral mucosa is assigned to a diet
    except for sweets and carbohydrates restriction, rich in vitamins and

    In the treatment of candidiasis of the oral mucosa are used polyene
    antibiotics - Nystatin, Levorinum 500 thousand units.. 4-8 times per day such
    , the daily dose of 2-4 million units. preparation on a course of treatment - 56 million
    u for 14 days. It is advisable to chew and suck the tablet, because
    in the gastrointestinal tract polienonye antibiotics bad
    absorbed. Regression of clinical symptoms of candidiasis has been underway
    5-6 day reduces redness, swelling, loosening mucous membrane
    oral epithelialization observed erosion.

    Amphotericin B is assigned in cases of lack of efficacy after
    use of Nystatin, levorin. Similarly, the action has
    Amphoglucaminum. Dekaminovaya caramel 1 caramel 6-8 times a day.
    Nizoral, Lamisil.

    Multivitamins with micronutrients, 2-3 pills a day for 1 month.
    B vitamins - B2, B6; C, PP et al. Vitamin B2 (riboflavin)
    It has some fungicidal governs
    redox processes, takes part in the processes
    carbohydrate, protein and fat metabolism.

    Calcium (calcium gluconate, calcium glycerophosphate, lactate
    calcium) as a restorative and hyposensitization. Preparations
    pantothenic acid - 0.1 g calcium pantotent 3-4 times per day
    for 1 month.

    Iron supplements (pills ferropleks, konferon tablets
    reduced iron). Aloe iron, and other gemostimulin
    drugs, since it is proved that when there is a change and candidiasis
    disturbance in iron metabolism.

    Desensitizing therapy - diphenhydramine, suprastin, pipolfen, Phencarolum.

    Patients suffering from long-term chronic forms of candidiasis,
    need constant admission of sedatives and tranquilizers,
    psychotherapy, hypnosis. Good effect gives auditory training, electrosleep.

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