Treatment of candidiasis oral mucosa requiresindividual approach to each case as candidiasis usually develops as a secondary disease caused by a decrease in the immunological defense, which can be caused by different reasons.
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What is Candidiasis
Candidiasis (thrush), yeast-induced
the fungus Candida albicans, manifested cheesy kind of raid on
oral mucosa. This plaque can be easily removed, leaving
behind the painful bleeding surface. With the progression
the disease can be observed the spread of the sky, the gums, the palatine
tonsil, larynx, the gastrointestinal tract.
Acute atrophic candidiasis, caused by often
is a long-term use of broad spectrum antibiotics, appears
painful, bleeding, swollen reddened mucosal areas
oral cavity and plaque curd can not be.
Chronic atrophic candidiasis occurs
usually those who wear dentures. It affects the mucous directly
adjacent to the prosthesis. Most often this occurs because of the soft tissue trauma
ill-fitting dentures, which can lead to chronic
inflammation. The affected area of reddened, swollen. Characterized by pain and burning.
Why there is oral candidiasis?
Microscopic fungus, often Candida albicans, is
a normal inhabitant of the oral mucosa. However, as conditions change
the existence of the causative agent of thrush can multiply rapidly. For
normal operation of the mucous membranes requires a stable weakly acidic medium,
normal microflora, necessary and sufficient amount of nutrients,
good blood supply, regular cleansing. A different situation arises when
changing conditions in which the yeast fungus lives. When you change the level of
pH (or pH), the appearance of cells in a significant amount of sugar,
or leaching beneficial flora suppression with antibiotics it at different
infections of fungi begin to multiply rapidly. There is a loss of cells
mucosa, develops oral candidiasis.
Treatment of oral candidiasis
Therefore, the main
trends in the treatment of a patient with candidiasis are:
- identification of the etiological factor underlying the pathogenesis of candidiasis in each individual case;
- elimination or reduction of further negative impact of these factors;
- pathogenetic therapy;
Based on the failure of the immune system with candidiasis,
especially for chronic low-intensity forms recommended candida
vaccine: monovalent, polyvalent and autovaccine.
With the same purpose in the arsenal of therapeutic agents for candidiasis can
find place pyrimidine derivatives - pentoksil 0.2 grams 3 times per day
for 3 weeks methyluracil 0.5 x 3 times a day treatment 3-4
weeks. The drugs stimulate the production of antibodies, phagocytic
Activity, stepping leucopoiesis, increase the content of gamma globulin
in serum, increases the regenerative capacity of tissue.
Gamma globulin hystoglobulin, gistaglobin 2 ml, 2 times a week,
in the course of 7-10 injections. After 2-3 months. treatment is repeated.
In the treatment of candidiasis of the oral mucosa is used on T-activin
40 ug per day by subcutaneous or intramuscular injection, for 7-10 days.
Kemantan 0.2-3 times a day, for 14 days. Either diutsifon 0.1-2 times
per day for 6 days. Spend 2-3 such courses with an interval of 1-3
day, under the control of biochemical and immunological parameters of blood.
Levamisole (dekaris) 150 mg 1 time per day for 3 days, hold 2
of course with an interval of 3-6 days. After 2-3 months of treatment is
repeat.
- restorative therapy, reduces mycotic sensitization and
and stimulating non-specific and specific resistance
organism;
- inclusion in the comprehensive treatment of antifungal drugs.
In the treatment of candidiasis of the oral mucosa is assigned to a diet
except for sweets and carbohydrates restriction, rich in vitamins and
proteins.
In the treatment of candidiasis of the oral mucosa are used polyene
antibiotics - Nystatin, Levorinum 500 thousand units.. 4-8 times per day such
, the daily dose of 2-4 million units. preparation on a course of treatment - 56 million
u for 14 days. It is advisable to chew and suck the tablet, because
in the gastrointestinal tract polienonye antibiotics bad
absorbed. Regression of clinical symptoms of candidiasis has been underway
5-6 day reduces redness, swelling, loosening mucous membrane
oral epithelialization observed erosion.
Amphotericin B is assigned in cases of lack of efficacy after
use of Nystatin, levorin. Similarly, the action has
Amphoglucaminum. Dekaminovaya caramel 1 caramel 6-8 times a day.
Nizoral, Lamisil.
Multivitamins with micronutrients, 2-3 pills a day for 1 month.
B vitamins - B2, B6; C, PP et al. Vitamin B2 (riboflavin)
It has some fungicidal governs
redox processes, takes part in the processes
carbohydrate, protein and fat metabolism.
Calcium (calcium gluconate, calcium glycerophosphate, lactate
calcium) as a restorative and hyposensitization. Preparations
pantothenic acid - 0.1 g calcium pantotent 3-4 times per day
for 1 month.
Iron supplements (pills ferropleks, konferon tablets
reduced iron). Aloe iron, and other gemostimulin
drugs, since it is proved that when there is a change and candidiasis
disturbance in iron metabolism.
Desensitizing therapy - diphenhydramine, suprastin, pipolfen, Phencarolum.
Patients suffering from long-term chronic forms of candidiasis,
need constant admission of sedatives and tranquilizers,
psychotherapy, hypnosis. Good effect gives auditory training, electrosleep.
