Atherosclerosis Treatment and prevention of complications


    Since atherosclerosis is a leadingcause such serious diseases as coronary heart disease, myocardial infarction, cerebral stroke, and so forth. Prevention and treatment of atherosclerosis should be given due attention. Modern approach to the treatment and prevention of atherosclerosis involves primarily the elimination of risk factors for atherosclerosis, which greatly reduces the risk of complications and deaths.

    Treatment of Atherosclerosis complex and includes a number ofmeasures for the correction of the image of the patient life style change in diet, avoiding harmful habits, as well as drug treatment, the recovery of the normal metabolism of the organism.

    Treatment of Atherosclerosis. Is it possible to treat atherosclerosis

    As we have discussed in our other articles,on the problem of atherosclerosis, the disease can be considered as one of the manifestations of the aging process. We also noticed that this statement is only half true, because at the same time, atherosclerosis is definitely a disease that is preventable and curable. Indeed, atherosclerosis can be treated!

    Recent clinical studies showthat each of atherosclerosis risk factors (obesity, smoking, lack of exercise, high blood pressure) increases the risk of atherosclerosis and its complications in 2 times, and the presence of one patient, several risk factors increases its chances of getting coronary heart disease, heart attack or stroke is 5 times! From this naturally begs the conclusion that the removal of atherosclerosis risk factors can slow disease progression and reduce the risk of deadly complications

    Drug-free treatment of atherosclerosis

    Atherosclerosis Treatment and prevention of complicationsThe essence of the non-drug treatment is reduced toelimination of risk factors and correcting the image of the patient's life with atherosclerosis. In this sense, of particular importance is the struggle with changeable risk factors for atherosclerosis:

    • Proper nutrition, reduce consumptionfoods high in cholesterol: compliance with a diet low in animal fats, consumption of foods rich in unsaturated fatty acids, avoiding overeating;
    • Fighting with obesity: maintaining body weight as close to the "ideal weight" significantly reduces the risk of diabetes, hypertension, coronary heart disease;
    • Quitting smoking and alcohol abuse: an important method of preventing atherosclerosis. Alcohol and tobacco have a negative impact on the condition of the vessels and the heart;
    • Increasing physical activity: helps improve heart and supply the heart muscle with oxygen, promotes weight loss, prevents the development of hypertension and diabetes;
    • Eliminating stress and fatigue: helps regulate the nervous and endocrine systems and to establish the normal body metabolism.

    In general, for the prevention and treatment of atherosclerosisneed not comply with any "special" mode. It is enough to lead a healthy lifestyle. Research has shown that the removal of one risk factor for atherosclerosis reduces the risk of complications doubled. Eliminating all the factors significantly improves the prognosis of the disease.

    Drug treatment of atherosclerosis

    Atherosclerosis Treatment and prevention of complicationsThe main purpose of medical treatmentAtherosclerosis is the reduction of cholesterol concentration in blood and restore fat metabolism in the body. The transition from non-drug to drug treatment is appropriate in those cases where, to reduce blood cholesterol levels can not be due to any correction of lifestyle, nor by diet. At this point in the treatment of atherosclerosis, the following groups of drugs: statins, fibrates sequesters fatty acids, nicotinic acid and its derivatives.

    Drug treatment of atherosclerosis Providence under the control of the physician. Independent use of drugs is strictly prohibited as described above.


    By the statin group includes drugs such as Lovastatin, simvastatin.

    The mechanism of action of statins isinhibition of cholesterol synthesis in the body cells and reducing the concentration of cholesterol in the blood. Statins also stabilize atherosclerotic plaque and prevent the occurrence of complications related to its destruction.

    Adverse reaction is a statin: headaches, dizziness, diarrhea, constipation, nausea, bloating, cramps, itching, sleep disturbances. The incidence of side effects from statin treatment, however, is minimal, subject to proper dosage regimen.

    Contraindications: pregnancy and lactation, acute liver disease, trauma, surgery, infection, severe endocrine diseases, hypersensitivity to the drug.


    By the fibrate group are gemfibrozil, fenofibrate, Ciprofibrate.

    Fibrates act by cleaving enzymes speed up blood fats, which in turn reduces the concentration of fat (including cholesterol) in the blood.

    Adverse reactions using such as fibrates and statins described above. In rare cases the use of a fibrate can cause anemia.

    Contraindications: pregnancy and breast-feeding, liver disease and gall bladder, kidney failure, increased sensitivity to the drug.

    Curtailments of bile acids

    This group of drugs include Cholestyramine, Colestipol.

    Curtailments prevent the absorption of bile acidsbile acids from the gastrointestinal tract, which in turn reduces the level of cholesterol. As sequesters bile acids inhibit cholesterol absorption from foods. Medicines themselves from this group are not absorbed into the bloodstream, and therefore are well tolerated by most patients.

    Side effects: nausea, diarrhea, constipation, exacerbation of peptic ulcer disease, exacerbation of hemorrhoids, and others.

    Contraindications: pregnancy and lactation, biliary tract diseases, hypersensitivity to the drug.

    Nicotinic acid and its derivatives

    Niacin is known as vitamin PP.

    The mechanism of action of nicotinic acid is to accelerate the transformation of the body fat, resulting in a decrease in their concentration in the blood.

    Side effects: hot flushes, redness of the face and upper body, itchy skin, increased blood glucose levels, worsening of peptic ulcer and gastritis, abnormal heart rhythms, formation of stones in the biliary tract.

    Contraindications: severe hypertension, peptic ulcer, pregnancy, breastfeeding, hypersensitivity to the drug, gout.

    Treatment of concomitant diseases

    atherosclerosis patients often suffer from othercomorbidities that increase the risk of complications of atherosclerosis. Atherosclerosis, in turn, complicates the course of these diseases. Therefore, a comprehensive treatment of the patient with atherosclerosis should include and treatment of diabetes, the treatment of hypertension, treatment of obesity.

    Surgical treatment of atherosclerosis

    Surgical treatment of atherosclerosisapplied in the case of certain lesions of artery walls that violate the blood supply to a particular part of the body and can be removed surgically.
    Typically, surgery involvesremoval of the affected area of ​​the blood vessel, removing thrombus or prosthetic blood vessels. These treatments are used for the treatment of atherosclerotic lesions of arteries of the lower limbs, coronary arteries of the heart, internal organs of the arteries.

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