Hemosorption

Content

  • About hemosorption
  • Readings for hemosorption
  • Contraindications for conducting hemosorption



  • About hemosorption

    Gemosorption is blood transmission in a special device through an artificial filter consisting of synthetic materials (for example, activated carbon), which are easily absorbed and precipitated «Heavy» Molecules toxins. The hemosorption procedure provides for the return of patient of purified blood, while toxins that caused the pathological process remain in the sorption box.

    HemosorptionThe difference between the methods of efferent therapy is the procedure and in the effects rendered on the body. If plasmapheresis has large immunocoregrating and reoccuping (normalization of blood flow) effect, then hemosorption is a large detoxifying effect.

    The differences are based on biophysical laws: some toxic substances have free radicals in the structure of the molecule structure,.E. they are electrically charged, so they are able to fix on the sorbent; But many pathological substances have a closed structure and therefore electrically neutral (for example, immune complexes, some types of allergens, cholesterol, etc.). Electrically neutral substances are not delayed by the sorbent. Accordingly, in this case, the plasmapheresis will be a more effective procedure at which the plasma is removed, along with soluble pathogenic complexes.

    After the first procedure, a significant decrease in the concentration of pathological products is observed, but after a few hours their concentration in the blood increases and approaches the initial. It is explained by the fact that substances dissolved in tissue and cell fluid are actively separated into the vascular channel. Remove these substances may subsequent efferent procedures, which leads, ultimately, to a decrease in the concentration of pathogenic substances in the body and long-term remission (absence of manifestations of the disease) or even recovery. Therefore, at least 3 procedures are recommended to achieve a persistent positive effect.

    Absolute Poams remain an absolute indication for hemosorption.

    Among the various methods of extracorporeal hemocorrection, hemosorption is distinguished by simplicity of contour, unnecessaryness of expensive equipment. The main operating component of the contour is hemosorbent. This is granulated carbon material, exposed activation, demineralization, depirogenization, hydromechanical processing, ion balancing and sterilization. Gemosorbent is used to remove a wide range of substances of low and medium molecular weight, gram-negative bacterial flora and its endotoxins from the blood of patients.



    Readings for hemosorption

    The main indications for conducting hemosorption are:

    • abstinence syndrome during drug addiction, toxicism, alcoholism;
    • manic and depressive states in mental illness and states;
    • Acute poisoning by sleeping medications, chlorine and phosphorodorganic compounds, alkaloids, salicylates, heavy metals.



    Contraindications for conducting hemosorption

    The main contraindications for conducting hemosorption are:

    • all types of bleeding;
    • violation of blood coagulation system;
    • BCC deficiency;
    • resistant hypotension;
    • electrolyte disorders;
    • impairment of hemodynamics;
    • cardiovascular failure;
    • Heavy violations of liver and kidney function.

    Leave a reply