Registration of cases of chlamydia, we started only 15 years ago. During this time, huge steps are made in the diagnosis and treatment of this infection. But the more scientists study Chlamydia, the more surprises it presents!
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About cavaria
La tells the head of the therapeutic department Vladimir Markovsky.
Question number 1. Vladimir Borisovich, which is chlamydia? What is the feature of this parasite?
Chlamydia belongs to a special class — They occupy an intermediate position between bacteria and viruses. The indigenous difference from viruses is that they cannot reproduce themselves, and chlamydia can. Chlamydia is very small in size and have similar to viruses of development cycle, it is an intracellular parasite.
Chlamydia can move very quickly into the L-form — the state when the parasite loses its typical structure and acquires a protective shell. This struggle for survival. In this form, the pathogen cannot multiply, but it can survive unfavorable conditions.
Question # 2. And what is this condition?
For example, antibiotics. Chlamydia does not like her very much when her «treat». This is an intracellular parasite, it is not at all interested in being expelled from there. For chlamydia it is characteristic that the treatment of antibiotics in just 7 days causes the formation of L-form.
Part of the chlamydium dies, and those who managed to go to L-shapes become for antibiotics «Impenetrable». And therefore after a while they can take their own former look and start actively multiply by occupying all new cellular territories.
That is, even when the clinical effect is reached, when the manifestations of chlamydia disappear, the person did not cure a person! And infection due to L-forms applies throughout the body — It becomes generalized. Most often therapy with antibiotics leads to a local improvement, that is, in the place of the entrance gate the process ends.
Question number 3. Well, the entrance gate of chlamydia is clear what: this is a sex infection!
And here you are mistaken! Not only. Entrance gates for chlamydia are any mucous membranes (eyes, nose, pharynx, genital organs). But mainly it is still sexually transmitted disease.
Depending on the entrance gate of chlamydia can cause various lesions. This chlamydial urethritis, which proceeds very sluggish, often asymptomatic, especially in men. As a rule, the disease remains unnoticed. In women, chlamydia is more commonly manifested, here is a more favorable environment for breeding chlamydia.
The purpose of antibacterial drugs leads to the fact that the local process ends. It can end and spontaneously, due to the immune system. But in most cases, against the background of local improvement, the infection is generalized, that is, from m
Eutle the entrance gate leaves and can save a very long time somewhere.
Question number 4. Where she hides?
In blood, in lymph nodes, in joints. Recently, chlamydia has become a large surgical problem. It turns out that the so-called aseptic necrosis of the hip head is almost half of the cases directly associated with chlamydial infection. This is not classical inflammation, because chlamydia does not live in the bones, but it forms mucous cysts, and bone «Foams». This can lead to complete destruction of the joint.
In general, the variants of chlamydial infection set. Chronic chlamydial infection — This is a huge problem. One American researcher said very much that there are only two types of diseases in human pathology — These are infectious diseases and actually infectious diseases.
Question number 5. That is, those diseases that we have always considered noncommunicable, actually caused by infection?
These states caused by chronic viral and bacterial infection. Even in the development of such a common disease, as atherosclerosis, chlamydial infection is played by the latter role. The permanent presence of the causative agent in the body causes immunodeficiency.
After all, what is any chronic disease? This is a series of exacerbations and remission. More academician I.IN. Davydov wrote that the phase of remission — This is not a period of temporary health, because the reason - in this case, Chlamydia - did not disappear anywhere. Therefore, the body even in a state of remission continues to deal with it.
This means that the immune system during atherosclerosis, and with other diseases, is always in the voltage phase. Chronic infection is accompanied by the release of inflammation regulators — cytokines that participate in the formation of atherosclerotic plaque. And in the plaques themselves, chlamydia is often found.
Question number 6. They say that the flu is not in itself, but with its complications. And what is the case with chlamydia?
Chlamydia is just dangerous precisely by its consequences: these are chronic diseases of the urinary sphere, a decrease in the erectile function, non-obstruction of pregnancy, infertility. These are complications of a local nature. But there are complications associated with the defeat of other organs.
Here you have an example: a young man, a junior sergeant of railway troops fell ill with sharp chlamydial urethritis. As a result, he blinded on one eye, he had to put the endoprosthesis of the head of the hip - this is in twenty years! That's what chlamydia is. Incorrectly or not fully cured infection is a greater danger to the body.
Since the infection is prone to transition to chronic, immunodeficiency is always present, the overvoltage of the immune system, which will definitely affect
In the future: the earlier development of atherosclerosis, bone destruction, the formation of mucous cysts.
Question number 7. It turns out, it is correct that in any diagnostic program requires a patient examination for infections?
The survey on the most actual infections is necessary, because infection even if it does not cause, it always complicates the course of any diseases.
In terms of diagnosis of chlamydia — This is an analysis of the urogenital scuffing method of PCR and, of course, the definition of the titer of antibodies in the blood. After all, in the chronic process, the causative agent in the blood is in L-form, so we rely here on antibodies. Titre High — Treat it!
Question number 8. And how do you treat?
Now the rule of treatment — Combination of antibiotics with rational immunotherapy. The sensitivity of chlamydia to antibiotics is known. Worse the situation with immunotherapy. Because the immune system is extremely complex, multifactorous, and there are no sufficient criteria to evaluate it. Such analyzes are very expensive and again the full understanding of the state of immunity does not give.
Question number 9. Then the question arises: what is rational immunotherapy?
This is a comprehensive impact on immunity. Treatment is prescribed depending on the age, the prescription of the disease, the presence of complications and T.D. In the destination can be included in various combinations of T-activin, polyoxide, inductors of interferon, complex of vitamins and others. Any patient here can help.
But the most important thing is: in the treatment regimen, a unique drug is necessarily present, which regulates the formation of glycoproteins — Basic bricks of cell membrane and receptors. Thanks to them cell «talks», There is a metabolism and energy. At the body level, this drug regulates all immune protection factors. It also has a direct antiviral action.
In addition, nonspecific biotimulation occurs: an increase in the sustainability of the body to stress, loads and t.D. After all, the immune system recognizes everything, and L-forms of chlamydia, too, but its reserves do not always have enough to combat chronic infection, for this it must be supported.
Question 10. After all this, the guarantor of our health is probably complete abstinence?
Well no! Full abstinence is not required. Although moderation will never hurt! The only guarantor of health is the state of immunity. After all, 10% of people have congenital immunodeficiency, they always suffer. 10% - these are people with a strong immunity, they do not hurt or sick very rarely. And in 80% of people — Including with us with you — The immune system depends on the conditions.
So you need to create conditions under which the immune system would always be guarded by our health. This is all that strengthens the immunity, ranging from the regime, refusal to smoking and t.D., Including the proper use of immunomodulators — Rational immunotherapy.
So, despite all the deceit of the pathogen and we have something to answer: Modern medicine can cope with chlamydia, and with its complications!
