Leptospirosis: Symptoms and Treatment

Content

  • Symptoms of leptospirosis
  • leptospirosis Treatment

  • Leptospirosis - a disease caused by a numbermorphologically similar pathogens belonging to the genus Leptospira infection source are rodents, pigs, cattle, horses, sheep and goats, dogs, birds.


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    imptomy leptospirosis

    Leptospirosis: Symptoms and Treatment
    The disease begins acutely with chills and fever during the
    days before 39,5-41S. At the same time there are severe headache,
    nausea, vomiting, abdominal pain. Characterized by pronounced muscle pain,
    mainly in the calf muscles, the muscles of the neck, abdomen, back and
    nape of the neck. Face puffy, bloodshot, scleral vessels injected.

    Quite often there is a polymorphic rash (urticaria, morbilliform,
    scarlatiniform, hemorrhagic), localized on the limbs and
    torso. Lymph nodes are enlarged, dense, painful, blood pressure decreased,
    Heart sounds are muffled, pulse lags behind the temperature level
    (Relative bradycardia). From the 2nd day of illness increases the size
    liver which becomes dense and painful to palpation. Stomach
    usually swollen, tongue dry, covered with brown patina.

    At high
    temperatures often develops on the background of severe intoxication
    toxic shock, which is one of the reasons
    death. In the acute phase of the disease is often observed
    kidney disease: there is pain, positive symptom
    Pasternatskogo, decreases the amount of urine, it discover
    erythrocytes, a large amount of protein, hyaline and granular
    cylinders.

    Often the onset of acute renal failure with increased levels
    urea, uric acid and creatinine in the blood. During the period of completion
    fever in some patients jaundice appears. In severe,
    often against a background of acute renal failure developed acute
    liver, leading to acute liver failure,
    encephalopathy and hepatic coma. Hemorrhagic syndrome is manifested in
    as hemorrhages in the skin at the injection site, petechial rash (melkie hemorrhage).
    hemorrhages in the sclera. Often there are signs of irritation
    meninges or marked meningeal syndrome (Kernig symptoms Brudzinskogo).



    leptospirosis Treatment

    The main method of treatment is possible early use
    antibiotics. Used by the introduction of specific
    immunoglobulin. In the treatment of patients with severe forms of leptospirosis,
    complicated by acute renal failure, great value
    acquires pathogenetic therapy. The most effective
    antibiotics are penicillins, intolerance they can
    use of antibiotics of the tetracycline group. The most effective
    treatment started before the 4th day of illness onset. The later of the beginning
    development of disease specific treatment begins, the worse the prognosis
    for patients.

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