All about Tularemia disease

Content

  • Tularemia
  • Sources of infection
  • Symptoms of Tularemia
  • Diagnosis of Tularemia



  • Tularemia

    Tularemia -
    Naturally focal infectious disease with lymphatic lesions
    nodes, skin, sometimes eyes, oz and lungs accompanied by
    pronounced intoxication.

    This infection is widespread
    In the countries of Europe, Asia and North America. On the territory of the Russian
    Federation there are a large number of foci.

    Pathogen
    Tularemia - Bacteria Francisella (Francisella Tularensis). She
    sufficiently stable in the external environment, but when boiling dies through
    1-2 minutes. The main source of infection - rodents (ondatras, rats, mice,
    Susliki, hares). Quite often infected hunters, farmers,
    fur harvesters, butchers - with contact with infected animals, with
    Cutting Tush.



    Sources of infection

    Carriers
    Tularevia are bloodsowing insects, the pathogen can also
    penetrate the intact skin or through the lungs - when inhalation
    dust, possibly mass infection through poorly cooked
    food and contaminated water - that is why tularemia is considered
    As likely biological weapons. Sick man danger
    for others does not represent, although the susceptibility of people to this
    infections are very high.



    Symptoms of Tularemia

    The clinical form of the disease depends on the path of penetration. Incubation period - from 1 to 30 days (more often than 3-7 days).

    Usually
    The disease begins acutely, with headaches, nausea, vomiting, temperature
    Body quickly rises to 39-40°C, chills appears. Face and Neck Leather
    blushing, poured blood vessels conjunctiva. A rash appears,
    which to the 8-12th day of the disease peels off, after it can stay
    Skin pigmentation.

    Later, more specific lesions arise, depending on the path of penetration of the pathogen:

    • All about Tularemia diseaseBubonne form
      It occurs if the introduction of microbes happened through the skin. Increase
      Nearest lymph nodes (in the form of bubes), later in the process
      Remote nodes can be involved.
    • Journal-bubonic
      The form develops more often when infecting insect bite. In addition to Bubon
      A shabby ulcer with raised edges appears at the bite,
      Dark crust covered.
    • Eye-bubonic
      Form - when penetrating the pathogen through the conjunctival. Characteristic
      Erosions and ulcers of conjunctivations with a yellow pus separation, sniffing buboons
      Lymph nodes.
    • Angic-bubonic
      Form - when using infected water and food. Proceeds in the form
      Heavy thoughts with necrosis of almonds, bribes in the submandibular, cervical
      and nearly surround areas.
    • Abdominal
      The form develops due to the lesion of the lempatical vessels of mesen.
      Manifests strong pain in the stomach, nausea, vomiting, sometimes
      - diarrhea.
    • Lungy The form arises
      When inhaling the pathogen. Lymph nodes of trachea, bronchi
      and mediastinum (easier option), or focus developing
      Pneumonia (proceeds quite hard and has a tendency to development
      complications).
    • Generalized form
      Reminds severe sepsis. Symptoms of intoxication are expressed: heavy
      Fever, weakness, chills, headache. Confusion may occur
      Consciousness, Brad, Hallucinations. Perhaps the appearance of a rack rash throughout
      body, bubones of various localizations, pneumonia. This form maybe
      complicate infephonic toxic shock.



    Diagnosis of Tularemia

    Diagnostics
    Tularemia in the first days of the disease presents significant difficulties.
    Help the doctor may reference to contact with rodents and t.D. Diagnosis
    clarify with the identification of serum antibodies to the causative agent
    and skin-allergic samples with Tulyarin. Valuable diagnostic method
    is an PCR (polymerase chain reaction).

    Tularemia
    treated under an infectious hospital. The main component
    Therapy - antibiotics that are applied by a long course.
    Also carry out disintellation and anti-inflammatory therapy,
    The need to maintain the functions of the internal organs.

    Large abscesses arising from the suppuration of lymph nodes are opened and drained.

    Mortality
    the absence of appropriate treatment is 6%, death comes
    As a result of generatization of infection. At the passing Tularemia
    remains steady lifelong immunity.

    Prevention of the disease
    In endemic areas, comes down to fighting rodents. If in animals
    Tularevia is found, the population is carried out preventive
    Vaccinations.

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