Iersinioz - this infectious disease relatedzoonoses. Zoonoses - is infectious and parasitic diseases in animals. The man - infectious diseases, pathogens which are the source of the animals. There are 7 species of Yersinia. Of these pathogens (ie, dangerous) for human are three types. It is the causative agent of plague (Yersinia pestis), pathogen pseudotuberculosis (Yersinia pseudotuberculosis), intestinal yersiniosis pathogen (Y. Enterocolitica).
Yersinia have antigens (gene) relationship with Salmonella, Shigella, Escherichia, Proteus, as well as Vibrio cholerae, the causative agent of tularemia and brucellosis.
Infectious disease yersiniosis named after A. Yersin. The disease can occur under the guise of dysentery, hepatitis, scarlet fever, appendicitis, catarrh (inflammation) of the upper respiratory tract.
Micro-organisms are very resistant to lowtemperature. In water at a temperature of 18-20 degrees to survive more than 40 days, if the temperature drops to 4 degrees - live 250 days. Yersinia can be stored in food (milk, bread), especially well preserved in fresh vegetables (carrots, apples) - up to 2 months. The frozen faeces stored up to 3 months, and at room temperature for - 7 days. Poor tolerate drying and heating. At temperatures above 60 degrees die within 30 minutes to 100 degrees - die immediately.
Yersinia susceptible to disinfectantsworking solutions at concentrations of antibiotic from the group of chloramphenicol, aminoglycosides, tetracycline, cephalosporins. they are not sensitive to penicillin and erythromycin.
The mechanism of occurrence and development iersinioza
The disease begins to increase sharplybody temperature, then there are abdominal pain, diarrhea mixed with blood and mucus. Once ingested with food or water are killed Yersinia partially acidic environment of the stomach, the other to penetrate further into the intestines. The primary pathological process develops in the small intestine. With sufficient virulence and sufficient numbers of pathogens, possibly, their penetration of the lymph vessels in the mesenteric lymph nodes, and the development of mesenteric lymphadenitis or mesadenitis (mesenteric adenitis - inflammation of the lymph nodes bryzzheyki). In these cases, yersiniosis at flows gastrointestinal or abdominal form.
When high virulence (ability to causethe development of the disease) and Yersinia reduction in immunological reactivity develops bacteremia (bacteria get into the bloodstream), which manifests the spread of infection. Pathogen well into the organs and tissues rich in lymphoid elements (liver, spleen, lymph nodes). In case of incomplete phagocytosis (i.e. incomplete destruction of the microorganism) Yersinia continuously circulate in the body, causing new foci of inflammation, including re pathogen enters the blood. Consequently, it may develop secondary to form focal lesions of any organ (heart, liver, joints, lung) or relapses and exacerbations occur.
The mechanism of development of yersiniosis (especiallysecondary focal forms, exacerbation and relapse) are important components of allergic, autoimmune processes, which manifests exanthema (rash), joint pain and arthritis.