Systemic dermatomyositis - disease ratherrare. The history of dermatomyositis disease reveals a direct relationship with inflammatory degenerative processes of the skin, impaired motor function, connective tissue disease and muscular. However, the muscle damage is a leading sign. Juvenile dermatomyositis and women - the most common form of the disease. The unequivocal answer to the question: "What is the cause of this disease," to date there. The object of study in medical science are still skin and muscular system of the body.
In adults, the disease is most likely to occur afterprolonged sun exposure, the action of some vaccines, viruses, and various infectious diseases. Sometimes, bacterial pathogens may also be the cause of the disease. In addition, the history of the disease "dermatomyositis" often is associated with genetic factors and genetic predisposition.
Classification divides idiopathic dermatomyositis disease origin and its flow.
The main symptoms and signs of illness atdermatomyositis is a general loss of large joints and skeletal muscles, heart and lungs, the gastrointestinal tract and the endocrine system. In the acute period of the history of the disease is manifested aching in the muscles of arms, legs and torso, which is reinforced with a significant physical activity. Stiffness in motion a vast proliferation of connective tissue is a sign dlitelnotekuschego process
A characteristic symptom of the disease iserythema - redness of the skin in the form of "points", which is located on the cheek bones, nose wings and nasolabial folds. Lesions observed in the upper parts of the chest, back, elbow, knee and finger joints.
In most cases, the disease develops as idiopathic process usually occurs after vaccination and is the most dangerous among other systemic diseases.
The peculiarity of this disease is the weakening of the functional activity of the gonads. Typically, in the pathological process involves the hypothalamus and the adrenal cortex.
A characteristic feature of the disease is a calcificationsoft tissue, which is based on the deposition of calcium in the muscle, which severely limits the patient's locomotor activity. This feature is common in juvenile form, at least - in adults.
With involvement in the disease process the throat muscles,larynx, esophagus, impaired speech, there are difficulty in swallowing and coughing fits occur. With long-term course of the disease is marked swelling and tenderness of the muscles, and in some cases - muscle atrophy.
In case of defeat intercostal muscles and musclesthe diaphragm may cause pulmonary and respiratory failure. Reduced ventilation lung function and symptoms of interstitial pneumonia - a clinical manifestation of systemic history of classical deramtomiozita.
Common symptoms of the disease manifest defeatshells heart attack, heart rhythm disturbances, enlargement of the liver in violation of its functional activity, abdominal pain, malaise, fever, and decreased appetite.
The basis of diagnosis of the disease isconduct histological examination and blood tests, both general and biochemical. This marked increase in erythrocyte sedimentation rate, leukocytosis, elevated liver enzymes and changes in uric acid levels.
In formulating a differential diagnosis should be carried out parallel with diseases such as systemic scleroderma, photodermatosis, periarteritis nodosa, erythema multiforme, lupus erythematosus.
The diagnosis is valid only in the case where there are the above characteristic of 2-3, and especially typical of this disease - cutaneous and muscular syndromes.