True pemphigus subdivided into several forms. The most common and most severe of which is pemphigus vulgar. That's about it often say, talking about this disease.
It begins vulgar pemphigus, as a rule,lesions of the mucous membranes of the mouth, there may be only there for a few months. Bubbles, revealing quickly form a painful bright red and covered with a whitish bloom erosion, bordered by fragments of mucosa - remains a bubble tires. Eruptions on the skin appear gradually, first in the form of single bubbles mainly on skin chest and back, then their number increases. Bubbles overgrown very slowly.
Bubbles are located on the outwardly intact skin,filled with clear content, they have different values. Having existed for a few days, they dry up, covered with crusts, or opened with the formation of erosions bright red color, abundant separating the thick sticky liquid. A characteristic feature of true pemphigus can be detected by light rubbing fingers on a healthy skin appearance. At the same time near the bubble, and sometimes at a distance from them there is detachment of the surface layers of the skin with formation of erosions. Furthermore, when tire shreds sipping for bubble detachment occurs far upper layers of the skin outside the visible erosion.
The general condition of patients early in the diseasebroken small. Worried the pain inflicted by erosion, especially strong on the mucous membrane of the mouth, making it difficult meal. Gradually, the condition deteriorates, there is a weakness, the temperature did not exceed 38 degrees. When festering blisters and erosions temperature can rise to higher numbers.
Characteristic of vulgar pemphigus isviolation of exchange of water and minerals. In the absence of proper treatment of the growing depletion leads to death. The duration of the disease (without treatment) is from 6 months to 2 years, in young patients with pemphigus vulgaris occurs more sharply.
Subacute malignant kindpemphigus vulgaris begin with lesions of the mucous membranes of the mouth from the flu, sore throat, remove and prosthetics. The skin is affected in 6-12 weeks. The disease is characterized by intensive growth of bubbles, their merger, forming extensive erosion, which hang on the edges of the white film.
The general condition of severe: marked weakness, headache, swelling and fever. Untreated disease leads to death within 3-6 months.