The concept of septic shock
In the blood of any person or by other meansregularly gets plenty of bacteria. A healthy person is not threatened, because it is usually the bacteria getting into the blood, rapidly absorbed by white blood cells - the cells responsible for the immune system. However, if the immune system is reduced, the immune system is unable to cope with microorganisms, which leads to sepsis - the development of human infection in the blood.
sepsis The danger is that the bloodstream infection spreads throughout the body, affecting vital organs. In some cases, sepsis leads to the development of septic shock.
Septic shock is a condition in which a result of the toxic substances produced by bacteria is a sharp, life-threatening lowering of blood pressure.
Typically, septic shock occurs in infants, people over 50 years and in patients with a weakened immune system.
The ideal situation for the development of septicshock are people with a reduced number of white blood cells - in particular, cancer patients or suffering from chronic diseases such as diabetes or cirrhosis of the liver.
The mechanism of development and the main symptoms of septic shock
Septic shock develops at the jointthe impact on the body of toxins that are produced by pathogenic bacteria, and cytokines, which are produced by its own human body to fight these bacteria.
There is expansion of blood vessels,It leads to a drop in blood pressure. This increases the heart rate and increases the amount of ejection of blood from the heart. In response to this also increases the permeability of blood vessels, causing blood enters the tissue, which leads to the formation of molasses, and impaired blood flow to vital organs - especially brain and kidney.
The body tries to raise the blood pressure and the blood vessels are narrowed, but in parallel there is a decrease in heart blood output, so blood pressure remains very low.
Once per day a person manifests confusionconsciousness, which is caused by deterioration of the cerebral circulation, chills, fever, rapid pulse. The patient breathes, the lungs are working hard, that leads to a reduction in blood carbon dioxide. Blood pressure rises sharply at first, then it drops.
Later, the body temperature may fall below normal insufficiency develops a number of organs, including the kidneys, lungs, heart.
More than 25% of cases of septic shock is fatal.
Diagnosis and treatment
Mandatory analysis in septic shock is a blood test. When septic shock is carried out monitoring of white blood cells, platelets and content of metabolic products (eg, urea nitrogen).
An electrocardiogram (ECG) monitor signs of cardiac arrhythmia.
In order to identify the causes of septic shock is performed blood cultures to determine the presence of bacteria and selection of further rational temperature.
Treatment of patients with septic shock is carried outonly in a hospital in a specialized unit. For high blood pressure intravenously injected a large amount of liquid. For vasoconstriction administered vasoconstrictor substances, such as dopamine. With the development of respiratory failure patient is transferred to artificial respiration. To combat septic shock using antibiotic therapy. Selection and appointment scheme of drugs is carried out by a doctor after the results of blood cultures.