Sepsis of newborn
Sepsis of newborn or neonatal sepsis - general
infectious disease, with bacteremia (bacteria from the source
infections into the blood). Infection of a newborn baby can
happen: antenatal (before birth), in intrapartum (during birth) and postnatal
(After giving birth) periods. The most susceptible to such disease premature
children. Subject neonatal sepsis does not lose its relevance for
a long time because it is too high percentage of deaths
Pathogens can be a variety of pathogens and
opportunistic organisms: staphylococcus, streptococcus, pneumococcus,
Salmonella, E. coli, Pseudomonas aeruginosa, and a number of other threatening
Human microorganisms. Availability
purulent and inflammatory processes in the mother, a long dry period,
skin damage during delivery - all this can become a source of infection
newborn baby. Bacteria and viruses can penetrate into the organism
path and gastrointestinal tract, as well as through skin damage, wound umbilical
and umbilical vessels. If sepsis is intrauterine origin, hearth
infection is in the body of the mother (placenta or any organ).
There are three main clinical forms of sepsis
newborns: early, late and nosocomial sepsis.
Detect early sepsis in the first 5-7 days of life, often
children infected perinatally, that is in the womb. Pathogenic
microorganisms enter the body transplatsentarno child (through the placenta).
Also, early sepsis may develop as a result of ingestion of amniotic
water or due to rupture of the amniotic membrane, which penetrates
pathogenic microflora of the vagina. Also possible infection in step
passage of the birth canal child, especially if there foci
Late sepsis detected 2-3 weeks after birth,
infection most often occurs during the period of the birth child
tract microflora mother's vagina.
Nosocomial sepsis is caused by pathogenic microorganisms,
which occurs in hospitals and maternity wards, most of the causative agent
sepsis becomes aureus (especially Staphylococcus epidermidis),
gramootritsatelnye sticks (including Pseudomonas, Klebsiella, Serratia, Proteus)
and fungi. The immune system of the newborn have not been prepared for such active
the effects of pathogens, mucosa and skin easily
vulnerable, whereby the risk of sepsis increases significantly.
Symptoms of neonatal sepsis
Most often sepsis is manifested through the following symptoms:
decreased appetite, refusal of the breast, frequent regurgitation, vomiting, grayish
skin, increased body temperature, a significant drop in body weight, cyanosis
nasolabial triangle, poor healing of the umbilical wound ( "weeping" navel).
Sepsis can occur in two forms: septicemia (total
intoxication, without the expressed foci of infection) and pyosepticemia
(The presence of explicit foci of inflammation: abscess, abscesses, pneumonia,
meningitis, osteomyelitis, etc.).
Sepsis can be a lightning occurs first 3-7 days
life, accompanied by septic shock ends, mostly lethal
outcome. The acute stage of sepsis lasts 4-8 weeks, protracted stage of sepsis may
last more than two or three months (most likely to occur in infants with
Treatment of neonatal sepsis
Infected children are subject to compulsory hospitalization
specialized departments of newborn pathology. Treatment is carried out
antibacterial agents broad-spectrum: semisynthetic
penicillin, ampicillin sodium salt, ampioks, tseporinom, lincomycin hydrochloride, gentamicin
sulfate etc. Antibiotics are often used in the form of intramuscular injections, and
an unfavorable course of sepsis and threatened states - intravenously.
The course of antibiotics usually lasts 7-14 days, long
course of the disease, as well as undulating and prolonged duration calls
a repeat course of antibiotics or of multiple courses of antibiotics.
And on each course are assigned different antibiotics, repetitions should be
Treatment continued until a stable therapeutic
Prevention of sepsis
Because sepsis severity of the disease, which is
most cases, leads to death, carried out a number of
preventive measures. These are: monitoring during pregnancy specialists,
timely diagnosis and detection of diseases and infections in pregnant