General Information about Carsile
Medicine Carsyl is included in the group of hepatoprotectors affecting liver cells. The active substance of this means is the vegetable component of Silimarine, which is obtained from fruits (seeds) Spotilla (Marin Tatarnik, Milk thistle).
Scientists and pharmacologists continue to study the mechanism of action of silimarine (this is a mixture of siliba, silicrystine, sildidianine). It has already been found that this component:
- Positively affects hepatocyte membranes (so called liver cells).
- Protects liver cells from negative impacts.
- Contributes to the restoration of damaged liver cells.
- Normalizes lipid exchange.
- Stimulates phospholipid production (these are special complex lipids that have the residue of phosphoric acid).
- Inhibits the development of fibrosis or fat rebirth of liver.
- Neutralizes poisonous compounds, toxic substances present in the blood.
- Normalizes blood circulation in the liver.
Thanks to Silimarina, Carsil contributes to improving the well-being of the host of his person, the laboratory indicators of the liver (bilirubin, transaminase and others) were normalized. Patients note that against the background of admission medication they have improved digestion. Appetite again appears. People with insufficient body weight gradually gain missing kilograms.
Most of the Karcila components (about 80%) after the work done is derived from bile, and the rest (about 5%) - with urine.
The drug is produced by the Bulgarian pharmaceutical company.
«Sopharma», Preparations of which are known all over the world. Carsyl is a dragee of a bone-colored shape having a brown color. The package contains 80 dragees, each of which contains 35 mg of silimarine. In addition to it, there are auxiliary substances - wheat starch, monohydrate lactose, poveidone, talc, microcrystalline cellulose, dextrose monohydrate, sorbitol, magnesium stearate, sodium bicarbonate, acacia gum, macrogol, celadesfat, sucrose, diethyl phthalate, titanium dioxide, gelatin, glycerol, dye.
In the pharmacy you can meet and packaging with the inscription «Karsyl Forte». This means that the box is 30 gelatin capsules of cylindrical shape. The capsules themselves are light brown, and inside there is a pale yellow or yellowish brown powder mass, from which light specific smell. In one such capsule, 90 mg of silimarine and auxiliary ingredients are present: lactose monohydrate, wheat starch, microcrystalline cellulose, polysorbate, povidone, mannitol, anhydrous silicon oxide colloid, sodium bicarbonate, crosspovidone, magnesium stearate. The shell consists of gelatin, titanium and dyes dioxide.
When Karsil is appointed?
Dragee (or capsules) need to swallow to meals by drinking water. Please note that the capsules do not need to open, and the dragee should not be able to! Typically, the course of treatment lasts at least 90 days (3 months). If the pathology is heavy, then an adult doctor may appoint 12 dragee per day (4 pieces three times). With a lung course of illness or for preventive purposes, it can be assigned a day 3-6 dragee (one dragee three times a day or two dragies also three times a day). If Karsyl is assigned a child, then the dosage and duration of the treatment specified by the pediatrician should be strictly adhered to.
Since in Carsyl Fort Silimarin is much more, it is more convenient to take it, just three capsules per day. Bioavailability in Carsyla Forte larger, its effectiveness is higher. In easily cases, it is enough to swallow one or two capsules per day. To prevent toxic liver damage per day take one or two capsules.
About contraindications and side effects
Carsil can not be taken in case:
- If the child is not 12 years old;
- during a period of acute intoxication;
- When the individual intolerance is detected, at least one of the components of the drug.
Pregnant and Nursing Breasts Women Carsil is not recommended, because there are no data on the safety of this hepatoprotector (the effect on the fruit and infants has been studied).
If the patient has violated the operation of the vestibular apparatus, then it should respect special caution while driving management or when working with complex mechanisms.
Caution should be observed if the drug is appointed to those patients who have hormonal disorders (with prostate carcinoma, ovarian carcinoma, uterine, breast, Endometriosis, Moma Mattik). This is due to the fact that estrogen-like action was detected in Silimarin.
If, together with Carsille, a woman takes oral contraceptives, their contraceptive effect can decrease.
Carsil can enhance the therapeutic effects of alprazolam, diazepama, lovastatin, ketoconazole, Vinblastine.
MirSets draws the attention of its readers to the fact that the preparation is wheat starch. Therefore, it is not prescribed to patients suffering from celiac disease, wheat allergies.
There are lactose and sucrose in the drug, so it is not used for the treatment of people who have revealed the intolerance to galactose or fructose, lactose lactation of LAPPA, glucose-galactose malabsorption.
As part of Carsila, there is glycerol, so some people can annoy the mucous membrane, lining the stomach, and provoke headache. With the appearance of such signs, it is necessary to report them to your doctor, then he will cancel the drug and will appoint a different hepatoprotector.
What else can be of unwanted effects? In rare cases - nausea, diarrhea, itching, rash on skin cover, hair loss.
Most patients with liver diseases are well tolerated by Carsley. And if they still appear some of the listed side effects, they quickly pass after the reception of the medicine stops.
