Hypogonadism female in childbearing age is noted by the underdevelopment of the sex glands, disruption of the menstrual cycle and amenorrhea. Sherezhevsky-Turner syndrome represents one of the options for primary hypogonadism with high secretion of gonadotropins - today the topic for discussion.
Endocrinological practice syndrome with lack of functional functions
The glands is regarded as a pathological condition due to
Violation of the production of gonadotropic and sex hormones. As a rule, this
Hormonal imbalance is accompanied by underdevelopment of internal,
outdoor genital organs and all signs of sexual
According to the classification of female hypogonadism, two hormonal options are distinguished:
- hypergronadotropic — develops with increased activity of steroid production cells of pituitary glands;
- Hypogonadotropic — It is characterized by a pronounced decrease in the synthesis of follicularity immuling and luteinizing hormone.
In addition, depending on the moment of the occurrence of the pathological process, distinguishes:
- Primary option — formed in the intrauterine period of life of the infant;
- secondary — There is an effect on the influence of adverse factors after birth, with the generated genitalia.
Clinical picture of hypergronadotropic hypogonadism: treatment and symptoms
Insufficiency of the ovarian function, combined
With primary amenorrhea, when at the age of puberty
Menstruation does not begin — The main signs of female hypogonadism.
What pathological symptoms should alert attentive mom
Teenage girls aged 12-14 years? First of all, it is complete
No menstrual cycle, even after the feud
ripening, dairy glands girls are not developed, on the pubis
And in the armpits, there is practically no exhaust. Figure
girls, her gait, high height, eunchoid body proportions for the first
look resemble a young man or teenager.
Hypogonadism, the treatment begins from the moment of detection
Diseases usually occur with congenital ovarian hypoplasia.
Sherosezhevsky-Turner syndrome is an example of a hypergronadotropic
states, while chromosomal changes cause a typical
Clinical picture of the disease. Patients with such syndrome
Non-low growth, short neck with characteristic fellows
folds, curvature of elbow joints, multiple bone
deformations, malformations of heart and vessels. With general inspection
It is noted that the dairy glands are not developed, the nipple is completely drawn,
There is no typical propagation, vaginal research confirms
underdevelopment of internal organs «infantile» uterus and ovarian
in the form of pancakes. Genetic and laboratory
The survey confirms the absence of sex chromatin and high
Level of gonadotropic hormones.
Hypergonadotropic hypogonadism, treatment with syndrome
Sherosezhevsky-Turner involves cyclic hormonal therapy with
Assistance of estrogen and gestagenov is subject to mandatory dispensary
Observation. Similar drug treatment helps to form
Secondary sexual signs, sexual belief and libido.
Hypogonadotropic hypogonadism is most often due to defeat
Hypothalamic-pituitary system or testicular tissue. Failure
ovaries can be caused by an autoimmune process, impact
Critical dose of ionizing irradiation, surgical removal
ovaries, androgensyntheing ovarian tumors. Such endocrine
Diseases like Isenko-Cushing syndrome, acromegaly, hypothyroidism,
Diffuse toxic goiter, Addison disease, adrenogenital syndrome
There may also be a reason for the reduction of the gonadotropic function of the pituitary.
The main manifestations of hypogonadotropic hypogonadism should be attributed
Violation of the menstrual cycle and infertility. Woman botherly
irregular menstruation, which, depending on the level of hormone
Insufficiency may come with delays up to 2-3 or more months.
When progressing hypogonadism, amenorrhea is observed or full
lack of menstruation and infertility.
Treatment of secondary form of hypogonadism begins with identifying causal
Factor that served as the basis for the development of syndrome. Correction of hormonal
changes helps to restore the menstrual cycle and overcome