Vitiligo

Content

  • Causes of vitiligo
  • Manifestations of vitiligo
  • Treatment of vitiligo
  • Prognosis and course of vitiligo



  • Causes of vitiligo

    • Diseases of internal organs and gloys of internal secretion (for example, diseases
      The thyroid gland is observed in 30% of patients with vitiligo)
    • Immune system disorders
    • Violation of the function of the nervous system and emotional stress
    • Chronic inflammatory diseases
    • Poisoning
    • Sunny burns



    Manifestations of vitiligo

    On healthy skin, multiple or single discolored (ivory colors appear
    bones) spotted rashes inclined to edge growth. On the edge of the stains celebrate
    condensation of pigment, which contributes to the sharpening contrast contrast
    rashes and healthy skin. Gradually the rash applies, and some
    Patients big areas of skin become snow-white. Vitiligo can be placed
    on any sections of the skin (except the skin of the palms and soles) and mucous membranes
    Shells. Hair on vitiligo spots are also discolored; In 35% of patients
    There is a premature Sedina. Subjective sensations are usually absent,
    However, 10% of patients celebrate itching.

    In 50% of cases, vitiligo disease begins at the age of 10—30 years. In children usually
    limited forms of vitiligo develop, often on the background of autoimmune and endocrine
    diseases (for example, thyroid diseases, rheumatoid arthritis, etc.). In the elderly, the disease is usually,
    does not develop.



    Treatment of vitiligo

    In the treatment of vitiligo use
    Preparations that increase the sensitivity to light in combination with
    Puv-therapy (ultraviolet light irradiation). Preparations,
    Raising sensitivity to light: Beroxan, Puvalen, Metoksalen,
    Occaled, Lamadin, Ammifurin, Meladinin, Psoralen, Psoberan. Preparations
    produced in the form of tablets, alcohol solutions for outdoor
    Applications, masses. The presence of contraindications for the PuU-therapy:
    Pregnancy, malignant tumors, increased sensitivity to
    irradiation, diseases of the stomach, liver, kidneys, cardiovascular
    Systems, blood, age up to 5 years and over 60 years.

    Vitiligo
    There is information about the successful combination of drug reception,
    increasing sensitivity to light, with the irradiation of the discredited
    Skin sites helium neon laser in the treatment of vitiligo. Application
    Laser during vitiligo has a number of advantages over the method of the PuUP therapy:
    High efficiency, significant reduction in treatment time, clarity
    dosing, lack of adverse reactions, limited
    Contraindications.

    Due to insufficiency in patients with vitiligo trace elements
    copper necessary to generate a skin pigment recommended
    Introduction of copper in the hearth vitiligo. So, there are data on the inclusion in
    Complex therapy of vitiligo Cupira, copper sulfate (reception inside or
    Introduction by electrophoresis), which increases the effectiveness of treatment.
    The simultaneous purpose of ascorbic acid eliminates the deficit
    Vitamin C, observed in patients with vitiligo, and contributes to successful
    Treatment.

    Due to the insufficient activity of adrenal glands in patients
    Vitiligo prescribe intramuscular injections of hormone corticotropin
    (daily at a dose of 10–20 units for treatment — 200–300 units) in combination with
    PuU-therapy.

    Vitaminotherapy is recommended to be carried out according to the scheme: 10–fifteen
    Vitamin B1 injections, alternating with nicotine acid, and intake
    Vitamin A, ascorbic acid with riboflavin.

    Surgical treatment of vitiligo: transplanting donor sites
    leather pre-prepared by the PuV method (which stimulates
    Synthesis of leather pigment and improves the transplant adhesion),
    It is a rapid treatment method, allows to achieve homogeneous coloring
    skin and is effective in the treatment of patients who did not help
    Methods of conservative therapy.

    Patients vitiligo recommended the exclusion of direct solar irradiation, the use of sunscreens.

    Diet therapy during vitiligo: the main goal of the diet – recovery
    Normal metabolism, increase in copper,
    zinc, iodine, iron and vitamins, as a possible cause of appearance
    diseases in the absence of an explicit source or as an additional
    strengthening during treatment. Copper products:
    Cod Liver, Fish, Seafood, Mushrooms, Pineapples, Bananas, Cherry,
    Raspberry, buckwheat, parsley, celery, figs, apricot, pear, blackberry,
    Malina, Cherry, Walnut Walnut, Melon, Bean (peas, beans, lentils).



    Prognosis and course of vitiligo

    In 20% of patients with vitiligo treatment is completely inefficient, especially with a big duration
    Diseases. Independent recovery in vitiligo occurs in 5% of cases.

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