Hyperprolactinemia - a condition which is characterized by
increased prolactin (pituitary hormone) in the blood. More often
hyperprolactinemia occurs in young women aged 25-40 years,
much less - in men of the same age.
Causes of hyperprolactinemia
The reasons that lead increase prolactin varied:
(Adenoma) of the pituitary - the most common cause of this condition. Typically, such
Tumor sizes are small (less than 3.2 mm). The word "tumor"
Doctors indicate increase in pituitary size is not cancer,
- Reduced thyroid function (hypothyroidism).
- ovarian disease (polycystic ovary syndrome).
certain drugs: anti-emetics (Reglan)
antidepressants (amitriptyline), contraceptives high
- Cirrhosis of the liver.
- Chronic renal failure (hyperprolactinemia occurs in 65% of patients on hemodialysis).
- brain diseases (meningitis, encephalitis, tumors).
syndrome of hyperprolactinemia is usually worried about the milk
of the breast is pregnant (galactorrhea), infertility, and violation of
menstruation (often lack thereof). Men are concerned about the decline
libido and potency, sometimes in conjunction with the release of milk.
In some cases there is excessive growth of body hair, tendency
to acne. As the pituitary tumor can be marked
blurred vision, headache.
Diagnosis and treatment of hyperprolactinemia
Diagnosis and treatment of hyperprolactinemia engaged endocrinologist and gynecologist-endocrinologist.
For the diagnosis it is necessary:
- cdat prolactin blood test (blood taken from a vein), in addition, your doctor may prescribe conduct hormonal tests;
some cases required blood tests and other hormones,
for example, thyroid hormones (if the doctor suspects a violation
- perform an X-ray of the skull and sella region to assess the size of the pituitary gland;
detailed assessment of the pituitary gland and the surrounding parts of the brain used
tomography - computed (CT) based on the use of
X-ray and magnetic resonance (MR), based
on the use of magnetic fields;
- Consultation of gynecologist (for women);
- the detection of pituitary adenomas need to consult an ophthalmologist.
hyperprolactinemia caused by a deficiency or hypothyroidism
the adrenal glands, is assigned the corresponding hormone
therapy, which leads to the normalization of prolactin and an end
If the condition is associated with drug taking
means (Reglan, amitriptyline, etc..), these drugs are overturned. how
Generally, after 4-5 weeks thereafter recovering menstrual
cycle and stops galactorrhea.
It is used most often. Patients prescribed special preparations
(Parlodelum, lisuride, etc.). This therapy normalizes content
prolactin, female menstrual cycle restores
and the ability to conceive.
(Removal of the pituitary tumor) is used usually in the presence of
violations by the vision and lack of efficacy
Radiation therapy is often used
all as adjunctive treatment after hypophysectomy or background