What is hyperprolactinemia


  • Causes of hyperprolactinemia
  • Diagnosis and treatment of hyperprolactinemia

  • Hyperprolactinemia - a condition which is characterized by
    increased prolactin (pituitary hormone) in the blood. More often
    hyperprolactinemia occurs in young women aged 25-40 years,
    much less - in men of the same age.

    Causes of hyperprolactinemia

    The reasons that lead increase prolactin varied:

    • Tumor
      (Adenoma) of the pituitary - the most common cause of this condition. Typically, such
      Tumor sizes are small (less than 3.2 mm). The word "tumor"
      Doctors indicate increase in pituitary size is not cancer,
      and benign.
    • Reduced thyroid function (hypothyroidism).
    • ovarian disease (polycystic ovary syndrome).
    • reception
      certain drugs: anti-emetics (Reglan)
      antidepressants (amitriptyline), contraceptives high
      estrogen content.
    • Cirrhosis of the liver.
    • Chronic renal failure (hyperprolactinemia occurs in 65% of patients on hemodialysis).
    • brain diseases (meningitis, encephalitis, tumors).

    syndrome of hyperprolactinemia is usually worried about the milk
    of the breast is pregnant (galactorrhea), infertility, and violation of
    menstruation (often lack thereof). Men are concerned about the decline
    libido and potency, sometimes in conjunction with the release of milk.
    In some cases there is excessive growth of body hair, tendency
    to acne. As the pituitary tumor can be marked
    blurred vision, headache.

    Diagnosis and treatment of hyperprolactinemia

    Diagnosis and treatment of hyperprolactinemia engaged endocrinologist and gynecologist-endocrinologist.

    For the diagnosis it is necessary:

    • cdat prolactin blood test (blood taken from a vein), in addition, your doctor may prescribe conduct hormonal tests;
    • at
      some cases required blood tests and other hormones,
      for example, thyroid hormones (if the doctor suspects a violation
      thyroid function);
    • What is hyperprolactinemiaperform an X-ray of the skull and sella region to assess the size of the pituitary gland;
    • for
      detailed assessment of the pituitary gland and the surrounding parts of the brain used
      tomography - computed (CT) based on the use of
      X-ray and magnetic resonance (MR), based
      on the use of magnetic fields;
    • Consultation of gynecologist (for women);
    • the detection of pituitary adenomas need to consult an ophthalmologist.

    hyperprolactinemia caused by a deficiency or hypothyroidism
    the adrenal glands, is assigned the corresponding hormone
    therapy, which leads to the normalization of prolactin and an end

    If the condition is associated with drug taking
    means (Reglan, amitriptyline, etc..), these drugs are overturned. how
    Generally, after 4-5 weeks thereafter recovering menstrual
    cycle and stops galactorrhea.

    Non-Surgical treatment
    It is used most often. Patients prescribed special preparations
    (Parlodelum, lisuride, etc.). This therapy normalizes content
    prolactin, female menstrual cycle restores
    and the ability to conceive.

    Surgical intervention
    (Removal of the pituitary tumor) is used usually in the presence of
    violations by the vision and lack of efficacy
    therapeutic treatment.

    Radiation therapy is often used
    all as adjunctive treatment after hypophysectomy or background
    therapeutic treatment.

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