Sarcoidosis causes and progression of the disease
Sarcoidosis is a chronic
inflammatory disease that affects mainly the lungs.
In Russia, sarcoidosis ill about five people out of 100 thousand.
Most sarcoidosis ill adults aged 30-40 years. Children
and the elderly rarely fall ill.
while the cause of sarcoidosis is unknown. Sarcoidosis is an inflammation, with
lymphocytes which are very active. these lymphocytes
produce substances that cause the formation of granulomas (accumulation
inflammatory cells) in various organs. The possibility of infection
sarcoidosis, the patient has not been proved, but there was a family history
diseases that can be attributed to either heredity or
the influence of environmental factors.
in patients with sarcoidosis are the first symptoms: fever, weight loss,
lack of appetite, fatigue. Some have a difficulty
breathing, particularly during physical exercise. Sometimes there is a dry
cough, muscle weakness and lethargy. In 90% of cases of sarcoidosis
It affects the lungs. However, in most cases of sarcoidosis
It can be detected only in X-rays, because it affects the intrapulmonary
lymph nodes and it does not cause the patients any external manifestations.
The most commonly found in lesions of the lungs following symptoms
shortness of breath, dry cough, chest pain, hemoptysis sometimes.
prolonged and severe disease inflammatory changes in the lungs
may contribute to the formation of pulmonary fibrosis and lower respiratory
function. Also in sarcoidosis often have inflammatory changes
the skin, eyes, joints and lymph nodes. Without
treatment of eye disease can lead to blindness. In sarcoidosis may
also damage the heart, brain, liver, kidneys and other internal
Diagnosis of sarcoidosis
The diagnosis of "sarcoidosis" sets
the therapist and patient after the inspection rasprosy. For the correct diagnosis
also need to conduct a full survey. The doctor is required to
prescribe a blood test from a vein, and chest X-ray. It may also
need to conduct tests to rule out TB Mantoux,
which is very similar in sarcoidosis manifestations. In sarcoidosis reaction
on the Mantoux test is negative. Also, it may be necessary research
lung function study on a special device to determine
respiratory capacity of the lungs.
Also required for diagnosis
holding a bronchoalveolar lavage. To this is introduced into the lungs
special flexible bronchoscope tube. It is used for taking
fluid from the lungs. The liquid is then examined for the presence of cells,
reflecting inflammatory process in lungs. To confirm the diagnosis
and may need lung biopsy. This procedure is carried out under the
local anesthesia, brief and painless. Because lung doctor
take a small piece of tissue using a special needle for
analysis under a microscope. If you have severe lung injury,
involved the heart, eyes and central nervous system, is the most
likely to require long-term treatment. If sarcoidosis
only affected lymph nodes in the lungs, it indicates
a favorable course of the disease.
Treatment and prevention of sarcoidosis
patients sarcoidosis disappears without treatment. However, the treatment of sarcoidosis
should take place under the constant supervision of a doctor, as a doctor
can assess the severity of internal organ involvement and appoint
correct, complete, and timely treatment.
serious complications of sarcoidosis are the development of respiratory
failure and blindness, which can lead to inflammation of the eye.
These complications can be prevented by destination
corticosteroids. In the course of treatment will be regularly
carried out an X-ray of the chest. Use of corticosteroids as
Typically, and inevitably involving the eyes, heart, brain and serious
cases of cutaneous manifestations. When inactive during sarcoidosis should
once a year to visit a doctor and do chest X-ray for control
for the course of the disease.
exacerbation of sarcoidosis should try to keep a healthy lifestyle.
The most important thing in the defeat of the lungs do not smoke, as it can
lead to breathing difficulties and complications of the disease. It should also be
avoid contact with drugs and chemicals that are harmful to the liver,
toxic volatile substances, dust, fumes, gases, which can
damage the lungs. In sarcoidosis there is an increase in calcium
in the blood which may lead to the formation of kidney stones, and urinary
bubble. Therefore, the use should be avoided rich foods
calcium (milk, cheese). For the same reason, do not sunbathe.