Rheumatism

Content

  • Causes and symptoms of rheumatism
  • Treatment: rheumatism


  • Causes and symptoms of rheumatism

    It is believed that the cause of rheumatism is activation
    pathogenic microorganisms, mainly beta-hemolytic
    streptococcus group A. That he plays the main role in the etiology and
    the pathogenesis of rheumatic disease. Firstly, the disease develops on
    against streptococcal infection. Secondly, in the blood of patients
    found a large number of antibodies to microorganisms that
    group. Third, the prevention of the disease was successfully held
    antibacterial drugs. Thus we have found out the cause of this
    insidious disease.
    Now consider what happens in the body
    human. For example, a person ill with angina that is exposed
    Effects of streptococcal infection. Normally, a person produces
    stable immunity to the antigens of the microorganism. But if safety
    forces of the body are reduced, then such immunity is not created. at
    re-introduction of streptococci in the body there is an immune complex
    answer. As a result of autoimmune reactions are damaged
    own connective tissue.

    Clinical manifestations are diverse.
    Typically, rheumatic fever develops within 1-2 weeks after undergoing
    streptococcal infection (eg, sore throat, scarlet fever, pharyngitis).
    Patients complain of an increase in temperature to 37.5, poor overall
    health (fatigue, sweating). Later, new features,
    indicating heart failure. These include a sense of disruption in
    the heart, palpitations, feeling of heaviness in the chest, shortness of breath. All
    These phenomena are associated with the development of myocarditis.
    In addition, there are pains in the joints (but not always). On examination,
    patient can detect lesions as a pale pink rings
    towering above the skin. On palpation they were painless. localized
    such rings mainly on breast skin of the abdomen, neck and face. Wherein
    pale skin.



    Treatment: rheumatism

    Rheumatism
    Depending on the flow are three
    the degree of disease activity: the maximum activity (acute), moderately
    active and with minimal activity (low current). The disease
    characterized by relapses (resumption of the acute process) under the influence
    adverse factors (infections, hypothermia, physical
    over-voltage, etc.).

    Complications include severe rheumatic conditions: endocarditis,
    thrombotic overlay on the valves can break off and spreads
    bloodstream to various organs and tissues, causing severe violations
    blood flow (ischemia) and consequently infarction (e.g., myocardial
    kidney, spleen, etc.). Severe disease can lead to
    rheumatoid pericarditis.
    If the patient enters the active phase of rheumatism, it is directed
    to be treated in hospital. Since the main etiological factor
    Rheumatic disease is streptococcus, the treatment is aimed at
    infection control, as well as inflammation caused
    these microorganisms.

    To fight with a streptococcal infection is assigned to antibiotic therapy.
    Most often used the following regimen:
    • penicillin 400 000 units 4 times a day administered intramuscularly (treatment 10 days)
    • then introduced bicillin 5 (this is also an antibiotic) at 1 500 000 IU 1 every 3 weeks (treatment 1,5-2 months)
    • then it is necessary to conduct a year-round bitsillinoprofilaktiku under medical supervision
    To suppress the inflammatory process, the doctor prescribes nonsteroidal
    anti-inflammatory agents. For example, diclofenac sodium (Ortophenum,
    voltaren), indomethacin, acetylsalicylic acid.

    If the patient has a high
    Activity autoimmune processes, appointed immunosuppressive
    therapy (suppresses the immune processes to damage
    own tissues). For this purpose, use corticosteroid
    drugs (prednisone). If the activity of autoimmune processes
    small, it is possible to assign aminohinolinovogo derivatives
    (Plaquenil, delagil).

    After discharge from the hospital, the patient
    cardiorheumatological should be observed in the study, with a view
    detect complications or prevent them, if none is available.

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