Sjogren's Syndrome, simple to the complex


  • Who is Sjogren (Sjögren), and why it is called a syndrome
  • Signs and symptoms of Sjogren's syndrome
  • Diagnostics and Prediction

  • Sjogren's syndrome (Sjögren) - a relatively raredisease in the population, but the second incidence of autoimmune diseases include, after systemic lupus erythematosus. There are different assumptions about the causes of the syndrome, among which the most popular is the viral theory in conjunction with a genetic predisposition.

    Who is Sjogren (Sjögren), and why it is called a syndrome

    Sjogren's Syndrome, simple to the complexHenrik Sjogren, or Sjogren is settled inRussian transliteration, the Swedish ophthalmologist, first saw the relationship between the dry eye, mouth and pains in joints and muscles, combining these into a single syndrome symptoms. Applying difficult at the time of research methods, have done a great work in this direction, thirty Sjogren was sure that he was right. In parallel, he has been working in this direction and the French ophthalmologist Henry Gougerot.

    Late in choosing a career clinician, SjogrenI had a vain hope of defending his doctoral thesis on this topic relatively early compared to their counterparts, but a fiasco, meeting skeptical reviews of his work from his colleagues. Only abroad, after some time, dry syndrome was recognized as existing, and the discoverer was awarded the title of professor in the twilight of his career and left his name in its title.

    When dry syndrome occurs with interconnectedother disorders, it is called a syndrome. If symptoms are described below in isolation from the rest of the healthy person talk about Sjogren's disease.

    Not to be confused with the syndrome of Sjogren's syndromeSjogren-Larsson. The latter has a completely different "inventors" - Sjogren and Larsson were Swedish psychiatrists, but the essence of their discovery is severe congenital syndrome. Mental retardation, cerebral palsy, and some form of congenital ichthyosis - skin changes characteristic of Sjogren's syndrome-Larsson.

    Signs and symptoms of Sjogren's syndrome

    Sjogren's syndrome in 90% of cases occurs inwomen, and the age of their often nearing the age of forty. Symptoms of Sjogren's syndrome, despite the clear obrisovannost can remain undetected for a long time, and attributed to stress, work with your computer, fatigue and lack of sleep, side effect of some medications.

    Violation of the cell structure of the external glandssecretion - the salivary, lacrimal, sweat, sexual, digestive glands creates a specific pattern, the elements of which can not be the same for the development of time and misleading diagnostician.

    The most common and classic symptoms of Sjogren's syndrome are:

    • Dryness, itching, feeling of sand in the eyes.
    • Dry mouth.

    Additionally, gastritis may be present,skin lesions, frequent cavities, nasal cavity lesions of unknown etiology, glomerulonephritis, peripheral vascular disease, neuropathy, pain in joints and muscles.

    Diagnostics and Prediction

    The manifestations of Sjögren's syndromeThe severity of individual syndrome,It meets its severe manifestation of the death and destruction of vital organs, most often - the kidneys. Most often the disease occurs with long periods of remissions and exacerbations rare.

    The forecast is also necessary to take into account the patient's response to therapy, which to this day remains a non-specific, and is aimed at the suppression of autoimmune reactions using hormonal methods.

    People living with Sjögren's syndrome have a higher risk of developing non-Hodgkin's lymphoma than the mean population and can have children with autoimmune disorders.

    Diagnosis of Sjogren's syndrome is difficult and is the objectification of data, as well as confirmation of the presence of characteristic changes in the structure of the glands using ray microscopy techniques and their tissues.

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