Sjogren's Syndrome: Symptoms, Diagnosis and Prognosis


  • Sjogren's syndrome, syndrome symptoms
  • Diagnosis of Sjogren's syndrome
  • Prognosis and treatment of Sjogren's syndrome

  • Sjogren's syndrome, syndrome symptoms

    Sjogren's syndrome - a chronic inflammatorydisease characterized by dry eyes, mouth, and other mucous membranes. This syndrome is often accompanied by symptoms characteristic of rheumatoid arthritis and systemic lupus erythematosus. Sjogren's Syndrome, according to experts, is
    auto¬immunnym disease, but the cause is unknown. It is less widely
    common than rheumatoid arthritis, and is more common in women,
    than men.

    Sjogren's Syndrome: Symptoms, Diagnosis and Prognosis
    With Sjogren's syndrome, leukocyte infiltration occurs
    glands producing liquid secretion, particularly the salivary and lacrimal
    glands. As a result of damage to white blood cells there are characteristic glands
    symptoms - dry mouth and dry eye irritation. at
    Sjögren's syndrome is sometimes also affects the mucous membranes,
    lining the gastrointestinal tract, trachea, vagina and vulva.

    Some patients have symptoms
    limited to dry mouth or sharp pain in the eyes. because of
    lack of tear fluid can significantly damaged cornea, and
    sometimes there is irreversible damage to the eye. Lack of saliva in the mouth
    leads to a blunting of taste and smell, and eating process
    become painful swallowing, quickly developing caries.

    Other people defeat affects many organs. For lack of
    mucus in the trachea and lung airways become more susceptible
    to infection, increased risk of pneumonia. Sometimes inflamed shell
    surrounding the heart - pericarditis develops. often damaged
    nerves, especially facial nerves. Defeat can affect the liver,
    pancreas, spleen, kidneys and lymph nodes. Arthritis
    It occurs in approximately 33% of patients affected with the same
    joints, as in rheumatoid arthritis. However, the syndrome of arthritis
    Sjogren less severe and does not usually lead to the destruction of joints.

    Lymphoma, a malignant tumor of the lymphatic system, develops in patients with Sjogren's syndrome 44 times more often than in other people.

    Diagnosis of Sjogren's syndrome

    When a person is marked dryness of the mouth,
    pain in the eyes and inflammation of the joints, is likely to Sjogren's syndrome. AT
    diagnosis helped by various studies. Thus, it is possible to evaluate the
    the amount produced by the lacrimal fluid: Place strip
    filter paper under the lower eyelid and measure its length humidification
    (Schirmer test). A person with a Sjogren's syndrome produces less
    one third of the normal amount of tear fluid. Ophthalmologist checks
    if there is damage to eyes.
    To assess secretion of the salivary glands, make more sophisticated
    research, such as scan or a biopsy of the salivary glands.

    The blood tests revealed pathological antibodies in the
    including highly specific for Sjögren's syndrome - for example, 85-B. Often
    Patients with Sjogren's syndrome also have antibodies that are more specific
    for rheumatoid arthritis (rheumatoid factor) or systemic lupus
    lupus (antinuclear antibody). erythrocyte sedimentation rate (ESR)
    elevated in 7 of 10 patients and in 1 of 3 decreased erythrocyte content
    (Anemia), or certain types of blood leukocytes.

    Prognosis and treatment of Sjogren's syndrome

    The prognosis depends on the ability of antibodies to damage life.
    vital organs. In rare cases, pneumonia, kidney failure, or
    development of lymphomas lead to death of the patient. Sjogren's Syndrome -
    an incurable disease, but the symptoms can be reduced. When dry eye
    using eye drops. If dry mouth is recommended
    and then sip a sip of liquid without chewing gum
    sugar, rinse your mouth. Avoid drugs that reduce
    salivation and thereby exacerbate this symptom: for example,
    "Cough" means and antihistamines. If
    damage to the salivary glands slightly prescribe the drug pilocarpine,
    which stimulates the production of saliva. Careful oral hygiene and
    frequent dental visits can minimize tooth damage.
    Soreness and swelling of the salivary glands are treated with analgesics. at
    Sjogren's syndrome symptoms of the joints is usually light, so that
    It is often sufficient to appoint an aspirin and rest. If there is bright
    expressed internal injuries corticosteroids are effective,
    such as prednisone, taken orally.

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