Sarcoidosis, diagnosis and treatment

Content

  • Sarcoidosis, manifestations of sarcoidosis
  • How to diagnose sarcoidosis
  • How to treat sarcoidosis



  • Sarcoidosis, manifestations of sarcoidosis

    Sarcoidosis is a disease of an unexplained reason characterized by
    Education of specific nodules. Ostroughly prevail
    Manifestations of sarcoidosis, but the defeats of all organs and systems are described,
    besides adrenal gland.

    The reason for the occurrence of sarcoidosis is considered to be a combination of genetic, environmental, infectious and immunological factors.

    One of the most characteristic manifestations of sarcoidosis of any type of flow
    is fatigue. Patients often celebrate only increased
    fatigue in the absence of any signs of the disease when inspecting.

    Dutch clinicians allocate 4 types of fatigue in sarcoidosis:

    • Morning fatigue, when the patient cannot rise from bed;
    • fatigue during the day, forcing the patient to teach himself to an intermittent pace of activity during the day;
    • Evening weakness, when the patient wakes up in the morning with an adequate energy, and feels «squeezed» By the evening;
    • Postssarcoidosny
      Chronic fatigue syndrome characterized by muscle pain,
      feeling fatigue, weakness and depression in the absence of external
      Signs of illness.

    Chest pain is frequent
    and an inexplicable sign during sarcoidosis. It has different
    Localization is not associated with the act of breathing, sometimes in sensations is
    on the verge between pain and discomfort.

    On the skin can be detected
    Purple-red, dense nodes that most often arise on
    Glands. When feeling, they can be painful, and in extrasion
    Process in their place for a long time, gray-purple is preserved
    Changing skin coloring.

    Inflammatory changes to the joints are transient, deformation of atypic.



    How to diagnose sarcoidosis

    Sarcoidosis, diagnosis and treatment
    Sarcoidosis is «Diagnosis of exception», because it is not
    contagious and not a malignant process. Currently the main
    The method of radiation diagnosis of sarcoidosis is X-ray
    High Resolution Computer Tomography.

    Among the others
    diagnostic methods for sarcoidosis (especially during primary examination
    or progression of the process) shows the implementation of ultrasound
    Surveys of liver, kidneys, heart, thyroid gland and small organs
    pelvis.

    Magneto-resonance examination informative
    Sarcoidosis of the central nervous system, liver, hearts. Lesions
    many organs during sarcoidosis confirm when scanning with Gallium and
    Technetsey.

    Study of the external respiratory function (recording of the curve
    Flow-volume of forced exhalation) during sarcoidosis in the early stages
    Reuses violations in the respiratory system.

    The obligatory component of the primary and annual survey of patients with sarcoidosis is an ECG.

    «Golden
    Standard» Sarcoidosis diagnosis has become a biopsy.
    Material can be taken from various organs - at biopsy
    peripheral limaftic nodes, leather, spleen, salivary glands,
    Liver and T.D. Most often it is the lungs, intragenic lymphatic
    Nodes and pleura are objects to take a tissue sample.



    How to treat sarcoidosis

    Accumulated world experience suggests that in 50-70% of cases
    The newly identified sarcoidosis gives spontaneous remissions (the disappearance of symptoms) that no
    Famous treatment today does not change the natural course of the disease.

    Before
    the appointment of hormone therapy, during the period of expectant tactics, may
    Vitamin E and N-acetylcisteine ​​(ACC, Fluimucil) should be appointed.

    Indication
    By the beginning of treatment with overall hormones are increasing
    Signs of the disease, an increase in the shadows on the radiograph and the decline
    Life tank and diffusion ability of the lungs, the involvement of the heart
    (rhythm or conductivity violations), neurological lesion (for
    the exception of the insulated paralysis of the facial nerve), eye damage, and
    Also a constantly elevated level of calcium in the blood.

    Sarcoidosis, diagnosis and treatment
    In patients with S
    such manifestations of the disease, like leaning of the skin, front will utter or
    Coughs apply local hormones (creams, drops, aerosols
    respectively).

    For most patients with identified
    intragenuous changes are suitable expectant tactics with
    Control on the 3rd and 6th months (radiography, blood test, calcium
    blood and urine).

    Inhalation hormones are prescribed as
    Preparations of the first line either at the stage of waste from hormones of general
    actions or patients with intolerance to system hormones.
    The feasibility of consistent and combined
    Applications of system and inhalation hormones.

    Anti-antimalaries
    Preparations - chlorookhin and hydroxychlorookhin possess a potential side effect
    action on the retina of the eye, which limits their application, however they
    not so dangerous if their daily dose does not exceed 250 mg. Higher
    Dosage requires observation from an ophthalmologist. Allergic are known
    Reactions to these drugs, they are also contraindicated during pregnancy.

    Methotrexate is widely used in chronic and resistant to sarcoidosis hormones.

    IN
    Azatioprine is also prescribed to hormone therapy,
    Cycloofosphamide, Cycloserine A, Hoormbucil, Colchicine, Allopurinol,
    Isotretionin, Talidomid.

    Plasmapheresis is recommended for patients with
    Hormone addiction, bad hormone tolerance,
    concomitant diseases (diabetes mellitus, ulcer ulcer
    and duodenal estate and others.), with a recurrent course. Spend
    2-5 procedures with an interval of 5-8 days.

    Physiotherapeutic
    Methods are widely used in the treatment of sarcoidosis - this is an order,
    phonophoresis with hydrocortisone on the chest, ultrasound with
    Hydrocortisone on the blade area, Industothermia, Laser therapy,
    Aloe electrophore with Novocaine.

    Unloading dietherapy
    It has long been applied in Russia at the I and II radiological
    Stages of sarcoidosis of the lungs. Its immunocirributing effect,
    Stimulation of adrenal cortex. Perhaps a combination with hormonal
    Treatment. Food is recommended to use bean, basil,
    Pomegranates, Sea Cabbage, Nuts, Fruits Seaner, Raw Seed
    Sunflower, Fruits of rowan black and black currant.

    From
    Fitotherapeutic tools can be recommended plant collection: take in
    equal parts of grass Highlander bird (dispatch), soul grass, leaf
    Salfa, Altea Root, Calendula Color, Platter. Mix. One
    Art. Spoon collection to fall asleep in thermos, pour 250 ml of boiling water, close
    thermos, insist 30 minutes. Strain, take 1/4-1 / 3 cup 3
    times a day 30 minutes before meals. Course - 45 days. After 3 weeks the course
    can be repeated. During the break between courses you can take a tincture
    Rhodians pink 25 drops 2 times a day - in the morning and at lunch (by
    Coordination with your doctor).

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