What is sarcoidosis? How to diagnose sarcoidosis? How to treat sarcoidosis? Answers to these questions you will find in the article.
Content
Sarcoidosis, manifestations of sarcoidosis
Sarcoidosis is a disease of an unexplained reason characterized by
Education of specific nodules. Ostroughly prevail
Manifestations of sarcoidosis, but the defeats of all organs and systems are described,
besides adrenal gland.
The reason for the occurrence of sarcoidosis is considered to be a combination of genetic, environmental, infectious and immunological factors.
One of the most characteristic manifestations of sarcoidosis of any type of flow
is fatigue. Patients often celebrate only increased
fatigue in the absence of any signs of the disease when inspecting.
Dutch clinicians allocate 4 types of fatigue in sarcoidosis:
- Morning fatigue, when the patient cannot rise from bed;
- fatigue during the day, forcing the patient to teach himself to an intermittent pace of activity during the day;
- Evening weakness, when the patient wakes up in the morning with an adequate energy, and feels «squeezed» By the evening;
- Postssarcoidosny
Chronic fatigue syndrome characterized by muscle pain,
feeling fatigue, weakness and depression in the absence of external
Signs of illness.
Chest pain is frequent
and an inexplicable sign during sarcoidosis. It has different
Localization is not associated with the act of breathing, sometimes in sensations is
on the verge between pain and discomfort.
On the skin can be detected
Purple-red, dense nodes that most often arise on
Glands. When feeling, they can be painful, and in extrasion
Process in their place for a long time, gray-purple is preserved
Changing skin coloring.
Inflammatory changes to the joints are transient, deformation of atypic.
How to diagnose sarcoidosis
Sarcoidosis is «Diagnosis of exception», because it is not
contagious and not a malignant process. Currently the main
The method of radiation diagnosis of sarcoidosis is X-ray
High Resolution Computer Tomography.
Among the others
diagnostic methods for sarcoidosis (especially during primary examination
or progression of the process) shows the implementation of ultrasound
Surveys of liver, kidneys, heart, thyroid gland and small organs
pelvis.
Magneto-resonance examination informative
Sarcoidosis of the central nervous system, liver, hearts. Lesions
many organs during sarcoidosis confirm when scanning with Gallium and
Technetsey.
Study of the external respiratory function (recording of the curve
Flow-volume of forced exhalation) during sarcoidosis in the early stages
Reuses violations in the respiratory system.
The obligatory component of the primary and annual survey of patients with sarcoidosis is an ECG.
«Golden
Standard» Sarcoidosis diagnosis has become a biopsy.
Material can be taken from various organs - at biopsy
peripheral limaftic nodes, leather, spleen, salivary glands,
Liver and T.D. Most often it is the lungs, intragenic lymphatic
Nodes and pleura are objects to take a tissue sample.
How to treat sarcoidosis
Accumulated world experience suggests that in 50-70% of cases
The newly identified sarcoidosis gives spontaneous remissions (the disappearance of symptoms) that no
Famous treatment today does not change the natural course of the disease.
Before
the appointment of hormone therapy, during the period of expectant tactics, may
Vitamin E and N-acetylcisteine (ACC, Fluimucil) should be appointed.
Indication
By the beginning of treatment with overall hormones are increasing
Signs of the disease, an increase in the shadows on the radiograph and the decline
Life tank and diffusion ability of the lungs, the involvement of the heart
(rhythm or conductivity violations), neurological lesion (for
the exception of the insulated paralysis of the facial nerve), eye damage, and
Also a constantly elevated level of calcium in the blood.
In patients with S
such manifestations of the disease, like leaning of the skin, front will utter or
Coughs apply local hormones (creams, drops, aerosols
respectively).
For most patients with identified
intragenuous changes are suitable expectant tactics with
Control on the 3rd and 6th months (radiography, blood test, calcium
blood and urine).
Inhalation hormones are prescribed as
Preparations of the first line either at the stage of waste from hormones of general
actions or patients with intolerance to system hormones.
The feasibility of consistent and combined
Applications of system and inhalation hormones.
Anti-antimalaries
Preparations - chlorookhin and hydroxychlorookhin possess a potential side effect
action on the retina of the eye, which limits their application, however they
not so dangerous if their daily dose does not exceed 250 mg. Higher
Dosage requires observation from an ophthalmologist. Allergic are known
Reactions to these drugs, they are also contraindicated during pregnancy.
Methotrexate is widely used in chronic and resistant to sarcoidosis hormones.
IN
Azatioprine is also prescribed to hormone therapy,
Cycloofosphamide, Cycloserine A, Hoormbucil, Colchicine, Allopurinol,
Isotretionin, Talidomid.
Plasmapheresis is recommended for patients with
Hormone addiction, bad hormone tolerance,
concomitant diseases (diabetes mellitus, ulcer ulcer
and duodenal estate and others.), with a recurrent course. Spend
2-5 procedures with an interval of 5-8 days.
Physiotherapeutic
Methods are widely used in the treatment of sarcoidosis - this is an order,
phonophoresis with hydrocortisone on the chest, ultrasound with
Hydrocortisone on the blade area, Industothermia, Laser therapy,
Aloe electrophore with Novocaine.
Unloading dietherapy
It has long been applied in Russia at the I and II radiological
Stages of sarcoidosis of the lungs. Its immunocirributing effect,
Stimulation of adrenal cortex. Perhaps a combination with hormonal
Treatment. Food is recommended to use bean, basil,
Pomegranates, Sea Cabbage, Nuts, Fruits Seaner, Raw Seed
Sunflower, Fruits of rowan black and black currant.
From
Fitotherapeutic tools can be recommended plant collection: take in
equal parts of grass Highlander bird (dispatch), soul grass, leaf
Salfa, Altea Root, Calendula Color, Platter. Mix. One
Art. Spoon collection to fall asleep in thermos, pour 250 ml of boiling water, close
thermos, insist 30 minutes. Strain, take 1/4-1 / 3 cup 3
times a day 30 minutes before meals. Course - 45 days. After 3 weeks the course
can be repeated. During the break between courses you can take a tincture
Rhodians pink 25 drops 2 times a day - in the morning and at lunch (by
Coordination with your doctor).