Hemophilia and family


    Family planning

    Hemophilia and familyGet information on how likely it is forYou give birth to a son with hemophilia, it is easy. The challenge is to decide what to do with this information, as it affects many family ties. Spouses need the help and support of experts from the center of hemophilia and other members of their family, local doctors and priests to make a decision about what they choose.

    Men suffering from hemophilia and women,are carriers of hemophilia, may decide to avoid the transmission of the abnormal gene to their children. The solution in these families need to take the couple together, and it will depend on many things, including knowledge and understanding of the problem of pain, which is associated with the disease, as well as the existence of the conditions for assistance for hemophilia in a particular region.

    For the family, which revealed severe hemophilia A or B selection bedet be as follows:

    • Do not have your children and others to adopt.
    • Conduct appropriate tests during pregnancy, and if the fetus is male, then the termination of pregnancy if it is allowed by local law.
    • Take the birth of a carrier of hemophilia or daughter to risk 25% of the 100 have a son with hemophilia, if the mother knows she is a carrier of the disease.
    • Select pre-implantation diagnostics, the genetic structure of DNA when coupled in vitro oocyte and sperm is examined for the presence of the abnormal gene.

    How to recognize hemophilia during pregnancy

    Hemophilia and familyThere are several research procedures that can be performed during pregnancy.

    An analysis of chorionic villi placental

    Due to take placenta tissue analysis comprisingfetal cells early in pregnancy. The analysis determined the floor of the hearth, and the presence of hemophilia gene. Analysis is possible in 70% of cases. With early detection of haemophilia disease in the fetus for the spouses becomes more acceptable at this stage to take a decision and to terminate the pregnancy. The risk of spontaneous miscarriage because this procedure is 1%. In very rare cases, it is applied to the fetus injury.
    Other procedures provide less relevant information and are held in the later stages of pregnancy.

    Amniocentesis (amniocentesis)

    During this procedure, at 15 weekspregnancy in a woman who according to the preliminary data of the bearer, is going to a certain amount of liquid formed around the fetus in the uterus. liquid cells are used to determine the sex of the fetus. There is a 1% risk of causing a miscarriage this procedure. If the fetus is male, then there is a choice - to terminate the pregnancy and avoid the 50% risk of having a boy with hemophilia patient. This diagnostic method may be useful in some cases and only when it is known that women in the family of previously detected abnormal gene.

    Research using fetal blood Fetoscopy

    This analysis can be carried out only inspecialized centers. It is performed at 18-22 weeks of gestation. If during the procedure fails to take the right amount of fetal blood, then it is possible to determine the level of factor VII or IX sufficiently reliably. The risk of spontaneous abortion in this case is 3%.

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