The pathogenesis of the period of infectious mononucleosis
When infectious mononucleosis penetratesairway epithelium leads to deformation and lymphoid tissue of the oral and nasal pharynx. Thus mononucleosis causes mucosal edema, enlarged tonsils and lymph nodes in the neck. Then, the virus enters the cytoplasm of B-lymphocytes, spreading throughout the body. When infectious mononucleosis spread throughout the body, then the body begins hyperplasia tissue.
If infectious mononucleosis resumesThe lymphocytes, then begins an active cell division and proliferation in the plasma cells, which in turn secrete immunoglobulins low specificity. Infectious mononucleosis is a disease so that even if the long-term exercise and proper treatment, the virus still remains in the body throughout life. As a result of the presence in the human body mononucleosis reduces immunity and can manifest itself at any time. If infectious mononucleosis expressed immunological reactions, then the disease can be considered a disease of the immune system, causing infectious mononucleosis complex belongs to the group AIDS - Associated diseases.
What triggers the occurrence of infectious mononucleosis
Infectious mononucleosis is caused by genomic DNAgerpesovyh virus family. This type of virus has the ability to replicate. But unlike other viruses which exist in the human organism, the genomic DNA does not disrupt the cells and leads to their destruction. On the contrary, the virus activates the cell proliferation (proliferation). Complete viral particles (virions) include specific antigens:
Each of these elements is formedsequence and is responsible for the synthesis of the respective antibody. If a person with infectious mononucleosis, the patient's blood appear antibodies to the capsid antigen and then develop antibodies to nuclear antigens and membrane. After drying, the causative agent of infectious mononucleosis quickly dies, so the virus can not be a long time in the environment. This phenomenon is due to the influence of high temperature and dezinfekantov.
The excitation source of infectious mononucleosisHe is a person who is present symptomatic or subclinical form of the disease. On the final days of the incubation period, and for 6-18 months after the primary carriers of infectious mononucleosis secrete virus infection, thereby contaminating the surrounding people. In 15-25 percent of healthy people as possible to discover mononucleosis in swabs of the oropharynx. If a person previously suffered a virus infectious mononucleosis, it has for a long time highlights the causative agent with his saliva.
How is infectious mononucleosis
Mononucleosis is transmitted by aerosol droplets through. Often, infectious mononucleosis is transmitted from a sick person or a carrier to a healthy saliva. The virus can be transmitted by kissing, sexual contactThrough arms, household items and toys. Not excluded that mononucleosis can be picked up by blood transfusion, as well as during childbirth.
Most people have a natural highsusceptibility to disease, but often dominated erased and mild forms of infectious mononucleosis. If the child during the first year of life is rarely ill mononucleosis, then this indicates an innate passive immunity, which is able to reject mononucleosis. When the state of human immunodeficiency infection causing infectious mononucleosis virus promotes generalization.
Symptoms of infectious mononucleosis
If during pregnancy the woman appearedthe first signs of infectious mononucleosis, then you need to urgently address to the doctor for further diagnosis. In addition, the doctor will prescribe appropriate treatment that will not harm the fetus and pregnancy in general. It is important to remember that delaying the visit to the doctor is unacceptable, because we all know that in pregnancy is very difficult to be treated for any disease. This is due to the fact that during the period of gestation of the child can not take strong drugs.
It is also worth knowing that the infectious mononucleosisIt can lead to serious complications, which have to be treated for a long time. And if mononucleosis appeared before pregnancy, you should wait for conceiving a child until they are cured of the disease. After all, if infectious mononucleosis develop into a chronic form, it may face the following consequences:
- changes in the blood;
- rupture of the spleen;
- fibrillation, Blockade, pericarditis;
- acute liver failure;
- sore throat;
If pregnancy appears at least one ofthe above conditions, it would have serious implications for the resolution of the situation. Besides, mononucleosis makes the body vulnerable to various infections, whose presence in women during pregnancy is absolutely not necessary. And the main thing! The virus that causes infectious mononucleosis is oncogenic, so our site advised to monitor their health and take care of yourself, especially if the disease appears during pregnancy.
How to treat infectious mononucleosis
Infectious mononucleosis mild to moderateforms can be treated at home. To do this, you need to comply with bed rest in severe intoxication. If mononucleosis occurs with the appearance of hepatitis B, then the diet is needed during the treatment of the disease. Also it helps treat mononucleosis gargling with antiseptic solutions. If patients present bacterial complications, then prescribe antibiotics.
If infectious mononucleosis flowshypertoxic with symptoms or with the threat of asphyxia, which can lead to swelling of the throat, and a marked increase in the tonsils, then needed a short course of oral prednisolone therapy (a drug that belongs to glyukortikoidam) for 3-4 days.