Chorionepitheloma is a disease whose development is associated with pregnancy pathology. The development of chorioneepithels is possible in the first month of pregnancy, when an active division of chorion occurs, from which the placenta is formed.
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The concept of chorionepithelometer
Chorioneepitheloma is a disease that is connected exclusively with pregnancy is found, fortunately, quite rare. Other His name - Horicarcinoma.
Already a few days after conception, the embryo appears shells. One of them - Chorion - is a variety of small porcers that penetrate between the porcelies of the motherboard of the placenta and provide the fetus nutrition and gas exchange. The root of chorion is beginning to be formed from the ninth day of life the embryo, and on the fourth week of pregnancy there is a particularly intensive development.
Actively breeding and dividing young chorion cells sometimes, unfortunately, «come down from the way», and are not turned into ripe cells of chorion, but in tumor cells. So in the body of a woman there are benign tumor tumor cells called «Bubble drift». Or - more rarely appear malignant cells of choriocarcinoma. In 20-50% of cases, the cells of benign bubble drift are also able to turn into «evil» Cells chorionepithelomes.
Thus, the development of chorionepithels can begin already on the fourth week of pregnancy. This disease is usually affected by women aged 25-35 years. Horionepitheloma may occur not only as a complication of bubble drift, but also as a complication of abortion - spontaneous or medical, ectopic pregnancy and even normally proceeded and already completed pregnancy. In the latter case, the tumor is diagnosed in the discern at the time of the diagnosis of a woman.
Basic symptoms of the disease
The main sign of the tumor is the appearance of unusual water-bloody discharge from the vagina. There is also a disturbance of the menstrual cycle (in non-embled women), the appearance of both uterine and vaginal bleeding, differing from menstrual bleeding with color and the amount of flowing blood.
Manifestations of metastases (tumor screenings) to other organs are also more often bleeding, since the cells of this tumor, spreading through the body, is more often settled near the blood vessels. Metastases are most often affected by the metastases of choriocarcinoma organs of the gastrointestinal tract, the urogenital system (kidneys, ureters, the bladder, the appendages of the uterus), as well as light, liver and brain.
Diagnosis of chorionepithelomes
Considering the seriousness of the disease, its early diagnosis becomes extremely important. The main thing is that the woman should make, for the first time, got pregnant, it is as soon as possible to take care of pregnancy in the women's consultation, and there is no inspection of the gynecologist regularly at the time of pregnancy, but after the birth of the child.
The doctor gynecologist, in turn, should keep the following indicators under its emergency control:
- The dimensions of the uterus (they should more or less fit the period of pregnancy)
- The level of chorionic gonadotropin in the blood of a pregnant woman, or a woman who received treatment for bubble drift (in the first two years after healing from this disease)
- X-ray picture of lungs (the first metastasis more often appear there)
- Picture of ultrasonic liver research, abdominal organs and small pelvis
- Appearance in the blood of a woman in-chorionic gonadotropin (in-choriogonin)
The appearance of in-chorionic gonadotropin (in-choriogonin) in the blood reliably indicates the presence of a malignant tumor in the body of a malignant tumor - choriocarcinoma.
Treatment of the disease
Treatment with a given disease depends primarily on the quantity and location of metastases.
In the case when metastases (tumor screenings) are not detected, the cure can be practically one hundred percent. With this form of the disease, chemotherapy is used - the use of drugs that overwhelm tumor growth and leading to its death. It is important that in the future recovered women almost always be pregnant and give birth to healthy children.
In the case when metastases are detected, chemotherapy can be combined with radiation therapy, which improves the outcomes of treatment.
With sustainable chemotherapy forms of the tumor, you may need to remove the uterus - hysterectomy.
When healing blood and from urine, pregnancy hormone disappears - chorionic gonadotropin, produced by a tumor, the uterus decreases and becomes normal, and the menstrual cycle is restored and becomes regular.
Despite the cure, for another two years, a woman must regularly undergo surveys from the gynecologist, as well as to protect against pregnancy with hormonal contraceptives at least during the year.
