Pharmacological properties
As a means of psychostimulating and exciting central nervous system, sodium caffeine-benzoate is a derivative of methylxanthine. It slows down the activity of special enzymes of phosphodestracy (FDE) in the heart, nervous system, organs and adipose tissue. In high doses, the body accumulates in the form of derivatives of adrenaline CAMF and CGMF.
This synthetic preparation, based on caffeine, is obtained from tea leaves and coffee seeds. Produce it in the form of tablets of 0.1 g, and everything in the package is 6 pcs. There is also a solution in ampoules (20%), dosage 1 ml.
Caffeine effects in tablets:
- increases mental excitability;
- helps to concentrate attention;
- improves mood;
- reduces fatigue and delays its appearance;
- stimulates the release of adrenaline in the blood;
- activates the fat burning process;
- During intensive training allows the muscles to actively use triglyceride (power supply);
- Increases muscle activity in people engaged in power sports: Participates in the exchange of calcium, maintains muscle membrane potential.
In small doses stimulates the central nervous system, and in large - on the contrary, inhibits. After taking caffeine-benzoate sodium, breathing becomes deep and rapidly, the vessels are expanding and the tone of cerebral arteries increases.
Reduced arterial pressure normalizes and slightly rises against the background of caffeine. In addition, caffeine contributes to the production of gastric juice, and is also a weak diuretic. Thanks to this, the kidney vessels are expanding, filtering increases in kidney gloms. Caffeine slows down the process «bonding» That is, platelet aggregations.
Sodium Bezoate Application Scheme
It is believed that the recommended caffeine dosage to stimulate the nervous system is not at all efficient when losing weight, because to burn extra pounds, you need to use other doses. If a person is experiencing a sport, then before each training, he needs to take from 9 to 20 mg of the drug in tablets per 1 kg of body weight. Only in this case will be able to disperse the work of the heart and speed up all metabolic processes. You need to drink 30 minutes before the start of training, and the reduction of the dose, according to athletes, will not have the necessary stimulating effect.
Doctors, in turn, advise not to rush and start receiving caffeine with 2 mg / kg, increasing the dose gradually.
Side effect of caffeine in tablets
Before starting the course of reception of Sodium benzoate, it is necessary to check how the body will react to the main component of the drug. If after the first day of treatment, the body has no negatively responded to caffeine, it means that you can continue therapy.
With independent use or non-compliance with the recommendations of the doctor may manifest a feeling of anxiety and anxiety. Usually the side effect is manifested by a headache, dizziness, insomnia and general malaise. Sometimes when contacting a doctor, the patient complains about nasal congestion, Nausea and vomiting as well as exacerbation Gastritis and ulcerative disease.
The sharp cancellation of the drug can lead to reactions and fatigue.
Contraindications to the use of sodium benzoate with caffeine are the following symptoms:
- Cardiovascular diseases;
- Allergy to caffeine and intolerance to it;
- alarming disorders;
- paroxysmal tachycardia;
- increased blood pressure;
- sleep disorders;
- Age up to 12 years.
With caution, you should take tablets to older people, with eye diseases, Epilepsy, as well as a tendency to cramps and supplies. Pregnant and lactating women can drink caffeine pills only by appointment of a doctor. With simultaneous reception of the drug with oral contraceptives, the activity of the caffeine is reduced, it is slower with the liver and accumulates in the blood.
To prevent the hyperstimulation of the nervous system, it is better to avoid the combination of sodium benzoate tablets with coffee and other substances containing caffeine. It is also important to take into account that caffeine is able to coal the calcium suction process in the gastrointestinal tract. It also reduces the effectiveness of sleeping preparations and drugs, contributes to the active absorption of heart glycosides and the removal of lithium with urine.
Symptoms overdose
Excess the daily rate of caffeine intake in tablets (300 mg) is fraught with such consequences:
- dizziness;
- heartbearance;
- nausea;
- confusion of consciousness;
- Anxiety and tremor.
Feeling the negative effects of the drug, it is urgently needed to wash the stomach, adopt a laxative and Activated carbon, which adsorb toxic substances in the gastrointestinal tract. People with chronic diseases of the stomach after an overdose caffeine can greatly exacerbate gastritis. In this case, you should contact a medical institution, where the doctor will be able to rinse the stomach in a timely and in a special solution and introduce an antacid agent. When convulsion caused by a large concentration of caffeine in the blood, anti-epileptic drugs are injected with intravenously.
After long research, scientists managed to determine the deadly dose of tablets of the sodium benzoate with caffeine, and this is what managed to fix. The positive effect of caffeine on the body is observed when receiving from 1 to 5 mg per 1 kg of human body weight. That is, with a weight of 70 kg, you can take from 70 to 350 mg of funds, but not more. People who do not use caffeine constantly, the effect of reception is much higher.
Each time, increasing the dose of medication, the likelihood of overdose is increasing. First reduces the total sleep time, its quality is reduced. Then appear headaches, insomnia and anxiety. The following admission above the permissible norm is fraught with rapid heartbeat and muscle twitching. A disorder of the gastrointestinal tract appears.
People dependent on caffeine tablets, as a rule, suffer from psyche disorders. Regularly excess of the dose of caffeine once can play a cruel joke against a person. Scientists have proven that the dose of gasoloate-sodium with caffeine is 100-200 mg per 1 kg of weight is fatal for humans. After the degenerate overdose, consciousness turns off, spasms appear and the lethal output occurs. From here it follows: life-threatening is the dose of more than 18 g of caffeine per day.
Daily taking caffeine pills, you should know that a sharp cessation of treatment leads to the oppression of the work of the central nervous system. Each organism is individual, therefore, the influence on the CNS may be different: one person will notice the tide of cheerfulness and forces, and the other will appear depression and drowsiness. The same effect happens on the heart.
The constant consumption of benzoate-sodium with caffeine during pregnancy can be fraught with spontaneous miscarriage, Violations of the work of the heart in the fetus and the slowdown in its development. In a small amount, the drug penetrates into breast milk, and after feeding the child he may have insomnia and excessive activity.
