This medicine is often recommended by their patients doctors. Readers Our site learn from the article on the mechanism of action of the drug, about the testimony for the use and methods of treatment. We warn about contraindications and possible unwanted effects.
What is the role of the liver
This body can be compared with the biochemical laboratory - so many diverse functions are assigned to it. Here are the main of them:
- Participates in the process of digestion, forming and highlighting bile.
- Neutralizes microbes, viruses, bacteria, poisonous substances, toxins coming with blood and lymph.
- In the liver, the splitting of drugs and other chemical compounds.
- Participates in blood formation and metabolic processes. Through the liver, nutrients are undergoing nutrients from the digestive system, as well as vitamins with minerals, they are processed here.
- It is synthesized by vitamins B12, a, different plasma proteins (albumin, protuberine, fibrinogen), ketone bodies, cholesterol, glycogen is stored.
If the liver activity is broken, it affects the state of the digestive, hearts, their work.
Composition and form of release
Heptralas are produced in the form of tablets, their shell dissolves directly in the intestines, and lyophilisate in vials (powder dried by a special method) used to prepare an injection solution (it is injected into the vein or muscle).
Active substance heptra is admethionine.
Tablet aids: sodium starch glycol, colloidal silicon dioxide, small-crystalline cellulose, magnesium stearate.
Inheist-soluble shell consists of polyethylene glycol, polymethacrylate, sytlecone, talc, polysorbate, purified water.
In addition to the active substance, the solvent ampoule includes: L-lysine - buffer solution of soda caustic.
How the medicine acts?
Heptral refers to the group of hepatoprotectors - preparations that positively affecting the work of the liver, increasing its protective properties. The active agent of heptrala, hitting the body, becomes a source of methionine - an important connection for the liver. In addition, adhemethionine stimulates the production of taurine, cysteine, some hormones, glutation and other biologically active components, resulting in a mechanism for neutralizing toxins, poisonous substances, harmful to the body. Such a process is called detoxification. If there is not enough glutathion in the body, hepatocytes become defenseless, weak in front of any harmful substances. Taurine reduces toxic effect on bile acid liver cells.
The stabilization of metabolic processes occurs, the formation of liver cell products (hepatocytes), for example, lipoproteins, factors of blood intake (abbreviated FGC) comes to normal. Bile stands out more active. The state of hepatocytes themselves improves, especially their membranes. The drug contributes to the formation of Putradescin, it is this substance that stimulates the process of liver regeneration, helps hepatocytes multiply. With prolonged use, the outflow of bile is improved, the pathological process is oppressed cirrhosis of the liver. The effect of such therapy is long, even if the course of treatment is completed, the positive effect of the medication is preserved about three months. Work in hepatocytes is complex, they produce more than one hundred different substances in which our body needs. Heptral regenerates damaged liver cells, restoring their functions. Prevents the splitting of connective tissue in the liver.
Another drug has a neuroprotective effect, significantly improves the work of the brain. Eliminates anxiety, symptoms of depression. Antidepressant properties manifest themselves to the seventh day of treatment
With osteoarthritis reduces pain, partial extension of cartilage tissue occurs due to improving the synthesis of proteoglycans.
In which diseases heptral helps?
The drug can be recommended when:
- cirrhosis, cholangitis, beless cholecystitis;
- chronic Hepatitis (including virus), liver dystrophy;
- liver failure;
- toxic lesions of the liver;
- Gross bile in the liver itself;
- Reception «heavy» medicines to which immunosuppressors, antibiotics, anti-tuberculosis agents, hormonal contraceptives;
- Alcohol abuse, drug addiction;
- passage of chemotherapy rate with antitumor agents;
- depressive states, encephalopathy.
About contraindications and side effects
This medicine should not be used in individual intolerance, the presence of stones in bile ducts, during breastfeeding and pregnancy, if there is no patient for another 18 years. If the medicine is appointed a nursing mom, then for the period of her treatment, you will have to stop feeding the baby breasts.
Sometimes patients taking heptral complain that they are worried about discomfort in the abdomen, diarrhea, heartburn. In some cases, allergic reactions appear on the drug (dermatitis or urticaria, in rare cases Outlet Quincke).
How to apply heptral?
Depending on the diagnosis and state, the patient heptral can be assigned inside (tableted form) or parenterally, that is, ampoules with a solvent are bought to carry out injections in the muscle or in Vienna. With heavy lesions of the liver First, the medicine is administered in the form of injections for two or even three weeks, and then the patient is discharged by tablets that should be drunk from two to four weeks continuously. Such a scheme of application is called speed. The number of tablets per day is usually assigned from two to four - it solves the attending physician. Our site draws readers attention to the fact that this drug must be taken between feeding food. The second important point is to do it better until 15 o'clock in the afternoon, because it has a small tonic effect. Tablets swallow the whole, do not need to rush them! Remove the tablet from the package it is necessary right before its admission. The injection solution is made in a bottle with lyophilisate, too, before the procedure. Pay attention to the fact that the powder in the bottle must have a white color if he suddenly became yellow, it cannot be used! Solvent can only be used by the one that was attached to hepta when buying. Introduce the medicine relies slowly.
When conducting a long course hepta, creatinine and urea in serum should be monitored.
Clinical trials and benefit experience show that heptral is useful for different liver diseases. Follow the recommendations of your doctor to not harm health.