As a means of psychoactive andcentral nervous system stimulant, caffeine, sodium benzoate - a derivative of methylxanthine. It inhibits the activity of specific enzymes fosfodiestraz (PDE) in the heart, nervous system, organs and fatty tissue. In high doses accumulated body as adrenaline derivatives cAMP and cGMP.
This synthetic drug, which is basedcaffeine, obtained from the leaves and seeds of tea and coffee. Producing it in the form of tablets of 0.1 g and the whole pack of 6 pcs. There is also the solution in the ampoule (20%), 1 ml dose.
The effects of caffeine tablets:
- increases mental excitability;
- It helps to focus;
- improves mood;
- reduces fatigue and holds its appearance;
- It stimulates the release of adrenaline in the blood;
- activates the fat burning process;
- during intense training allows the muscles to make greater use of the triglyceride (power supply);
- increases muscle activity in people engaged in power sports: involved in calcium metabolism, supports the potential of the muscle membranes.
In small doses, it stimulates the central nervoussystem, and large - on the contrary, oppresses. After receiving the caffeine-sodium benzoate breathing becomes deep and rapid, blood vessels dilate and increases the tone of the cerebral arteries.
Low arterial pressure normal and slightly increased in patients receivingcaffeine. Additionally, caffeine promotes the production of gastric juice, and a weak diuretic. This renal vessels dilate, increasing filtration in the renal glomeruli. Caffeine slows down the process of "glue" that is platelet aggregation.
The scheme of the sodium benzoate caffeine
It is believed that the recommended dosage of caffeineto stimulate the nervous system is not effective in weight loss, as to burn off extra weight, you need to use the other doses. If a person is overweight is engaged in sports, before each workout it needs to take between 9 and 20 mg tablets 1 kg of body weight. Only in this way will be able to accelerate the heart and accelerate all metabolic processes. Drink need for 30 minutes prior to training, and the dose reduction, according to athletes, will not have the desired stimulatory effect.
Physicians, in turn, are advised not to rush out and start taking caffeine with 2 mg / kg, increasing the dose gradually.
Side effects of caffeine tablets
Before you start a course receiving sodium benzoateyou need to check how the body responds to the main component of the preparation. If after the first day of treatment the body does not negatively reacted to caffeine, so it is possible to continue therapy.
With self-use or non-compliance with the doctor's recommendations can manifest feelings of anxiety and worry. Usually, side effects are headache, dizziness. insomnia and general malaise. Sometimes to see a doctor the patient complains of nasal obstruction, nausea and vomiting, as well as exacerbation gastritis and peptic ulcer disease.
Abrupt withdrawal of the drug can lead to lethargy and fatigue reactions.
Contraindications to the use of sodium benzoate caffeine are the following symptoms:
- diseases of the cardiovascular system;
- allergy to caffeine and its intolerance;
- anxiety disorders;
- paroxysmal tachycardia;
- high blood pressure;
- sleep disturbances;
- age up to 12 years.
Precautions should be taking pills for older people with eye diseases, epilepsyAs well as the tendency to convulsions and seizures. Pregnant and lactating women can drink the pills with caffeine only on prescription. At the same time taking the drug with oral contraceptives, decreases the activity of caffeine, it appears slower liver and accumulates in the blood.
To avoid overstimulation of the nervoussystem is best to avoid combination of sodium benzoate tablets with coffee and other substances containing caffeine. It is also important to note that the process of caffeine can inhibit calcium absorption in the gastrointestinal tract. It also reduces the effectiveness of sleeping pills and drugs, promotes active absorption of cardiac glycosides and the excretion of lithium in the urine.
Symptoms of overdose
Exceeding the daily norm of caffeine tablets (300 mg) is fraught with such consequences for the person:
- heart palpitations;
- anxiety and tremor.
Feeling the negative effects of the drug, it is necessary to urgently do a gastric lavage, take a laxative and Activated carbonWhich adsorbs toxic substances in the gastrointestinal tract. People with chronic diseases of the stomach after an overdose of caffeine can greatly aggravate gastritis. In this case, you should contact the medical facility where the doctor will be able to promptly wash the stomach with a special solution and enter the antacid. When the convulsions caused by high concentration of caffeine in the blood, the patient intravenously administered anti-epileptic drugs.
After much research, scientists were abledetermine the lethal dose of tablets of sodium benzoate, caffeine, and, behold, it was possible to fix. The positive effect on the organism of caffeine is observed when receiving from 1 to 5 mg per 1 kg body weight. That is, with a weight of 70 kg may be administered from 70 to 350 mg of agent, but no more. People who do not drink caffeine all the time, the effect of receiving much higher.
Each time, increasing dose of drug,it increases the likelihood of overdose. First, it reduced total sleep time, reduced its quality. Then there are headaches, insomnia and anxiety. Next intake above the allowed rate is fraught with heart palpitations, and muscle twitching. It appears disorder of the gastrointestinal tract.
Dependent on caffeine pills people likegenerally suffer from mental disorders. Regular excess doses of caffeine could one day play a cruel joke against the man. Scientists have shown that a dose of sodium benzoate, caffeine 100-200 mg per 1 kg of body weight is lethal to humans. After a fatal overdose disconnected consciousness manifested spasms and death occurs. This implies: a life-threatening dose is more than 18 grams of caffeine per day.
Daily taking pills with caffeine, you shouldknow that the abrupt discontinuation of treatment leads to the oppression of the central nervous system. Every body is different, and therefore the effect on the central nervous system may be different: one person noticed a surge of courage and strength, and the other will be depression and drowsiness. The same effect occurs on the heart.
The constant use of sodium benzoate, caffeine during pregnancy may be fraught with spontaneous abortion, Disorders of the heart in the fetus and the slowingits development. The small amount of the drug passes into breast milk, and after feeding the baby he can appear insomnia, and excessive activity.